SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lkj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1lkj CALMODULIN
(Saccharomyces
cerevisiae) 		4 / 8 LEU A   4
PHE A  12
PHE A  68
MET A  72
 None
 0.60A 1wrlC-1lkjA:
5.3
1wrlD-1lkjA:
5.6		 1wrlC-1lkjA:
28.03
1wrlD-1lkjA:
28.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 1lkj CALMODULIN
(Saccharomyces
cerevisiae) 		4 / 8 LEU A 143
GLU A 114
LEU A 116
LEU A 125
 None
 1.23A 5dxeA-1lkjA:
undetectable		 5dxeA-1lkjA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1lkj CALMODULIN
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 140
ILE A 135
ASP A  97
GLY A  98
 None
 0.88A 5h3aA-1lkjA:
undetectable		 5h3aA-1lkjA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1lkj CALMODULIN
(Saccharomyces
cerevisiae) 		3 / 3 LYS A  77
ASN A  79
SER A   2
 None
 0.98A 5yw0A-1lkjA:
undetectable		 5yw0A-1lkjA:
20.75