SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lkt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 8 ILE A  61
LEU A  65
ILE A  82
VAL A  80
ILE A  51
 None
 1.32A 1linA-1lktA:
undetectable		 1linA-1lktA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 8 SER A  20
ARG A  21
GLN A  99
ASP A 101
 None
 1.21A 1rs7B-1lktA:
undetectable		 1rs7B-1lktA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 8 SER A  20
ARG A  21
GLN A  99
ASP A 101
 None
 1.19A 1zzuA-1lktA:
0.0		 1zzuA-1lktA:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 7 VAL A  49
THR A  84
ILE A  47
SER A  89
 None
 0.84A 3deuA-1lktA:
undetectable		 3deuA-1lktA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 8 SER A  20
ARG A  21
GLN A  99
ASP A 101
 None
 1.07A 3n62B-1lktA:
undetectable		 3n62B-1lktA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA193_1
(DIHYDROFOLATE
REDUCTASE)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		4 / 5 LEU A  79
ILE A  16
PRO A  15
PHE A  17
 None
 1.14A 3s3vA-1lktA:
undetectable		 3s3vA-1lktA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_D_SVRD301_1
(NUCLEOCAPSID PROTEIN)		 1lkt TAILSPIKE PROTEIN
(Salmonella
virus
P22) 		5 / 11 GLY A  71
ALA A  95
VAL A  26
PRO A  15
ILE A  73
 None
 1.27A 4j4vD-1lktA:
undetectable
4j4vE-1lktA:
undetectable		 4j4vD-1lktA:
18.07
4j4vE-1lktA:
18.07