SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ll2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AVN_A_HSMA264_1
(CARBONIC ANHYDRASE
II)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 4 ASN A 188
HIS A 212
ASN A 133
GLN A 164
 None
MN  A 333 ( 3.4A)
UPG  A 334 (-3.4A)
UPG  A 334 (-2.9A)
 1.18A 1avnA-1ll2A:
0.0		 1avnA-1ll2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_A_EAAA223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 8 GLY A 162
LEU A  80
VAL A 152
PHE A 159
 None
 1.21A 1gsfA-1ll2A:
0.0		 1gsfA-1ll2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_B_EAAB223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 8 GLY A 162
LEU A  80
VAL A 152
PHE A 159
 None
 1.21A 1gsfB-1ll2A:
0.0		 1gsfB-1ll2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSF_D_EAAD223_1
(GLUTATHIONE
TRANSFERASE A1-1)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 8 GLY A 162
LEU A  80
VAL A 152
PHE A 159
 None
 1.21A 1gsfD-1ll2A:
0.0		 1gsfD-1ll2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		3 / 3 LEU A 245
TRP A 248
GLY A  18
 None
 0.78A 3l35A-1ll2A:
0.0
3l35H-1ll2A:
undetectable		 3l35A-1ll2A:
9.01
3l35H-1ll2A:
3.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		3 / 3 VAL A  21
SER A  25
LEU A 106
 None
 0.68A 3n8xA-1ll2A:
0.0		 3n8xA-1ll2A:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 4 LEU A  22
ILE A 111
GLY A  23
PHE A   6
 None
 0.84A 4dc3A-1ll2A:
2.7		 4dc3A-1ll2A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_A_TEPA402_1
(PYRIDOXAL KINASE)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 5 SER A 134
GLY A 135
THR A  83
ASP A 102
 UPG  A 334 (-3.2A)
UPG  A 334 ( 4.1A)
None
MN  A 333 ( 3.1A)
 1.04A 4eohA-1ll2A:
undetectable		 4eohA-1ll2A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_2
(HIV-1 PROTEASE)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		5 / 8 GLY A  18
ALA A 103
ASP A 104
ASP A 102
THR A  39
 None
UPG  A 334 (-3.3A)
MN  A 333 ( 2.1A)
MN  A 333 ( 3.1A)
None
 1.28A 4eyrB-1ll2A:
undetectable		 4eyrB-1ll2A:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 4 LEU A  92
LEU A   9
GLN A   4
GLU A 119
 None
UPG  A 334 (-4.2A)
None
None
 1.21A 4i41A-1ll2A:
0.0		 4i41A-1ll2A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		4 / 5 PHE A 100
HIS A 212
PHE A 137
PRO A 126
 None
MN  A 333 ( 3.4A)
None
None
 1.37A 4o8zA-1ll2A:
2.1		 4o8zA-1ll2A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		5 / 10 ALA A 153
LEU A 167
LEU A  84
SER A  69
ALA A  70
 None
 1.14A 4zbrA-1ll2A:
undetectable		 4zbrA-1ll2A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		3 / 3 ASP A 125
ASN A 133
ASP A 102
 UPG  A 334 (-4.1A)
UPG  A 334 (-3.4A)
MN  A 333 ( 3.1A)
 0.82A 5vopA-1ll2A:
undetectable		 5vopA-1ll2A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ll2 GLYCOGENIN-1
(Oryctolagus
cuniculus) 		3 / 3 ASP A 125
ASN A 133
ASP A 102
 UPG  A 334 (-4.1A)
UPG  A 334 (-3.4A)
MN  A 333 ( 3.1A)
 0.82A 5vopB-1ll2A:
undetectable		 5vopB-1ll2A:
22.80