SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ll8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1ll8 PAS KINASE
(Homo
sapiens) 		5 / 12 GLY A  85
PHE A  48
ILE A  81
LEU A  31
TYR A  34
 None
 1.08A 3o7wA-1ll8A:
undetectable		 3o7wA-1ll8A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1ll8 PAS KINASE
(Homo
sapiens) 		4 / 4 PHE A  48
LEU A  22
LEU A  39
VAL A 106
 None
 1.33A 5xxiA-1ll8A:
undetectable		 5xxiA-1ll8A:
12.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1ll8 PAS KINASE
(Homo
sapiens) 		3 / 3 LYS A  87
SER A  82
SER A  84
 None
 1.00A 6gbfA-1ll8A:
0.0		 6gbfA-1ll8A:
12.66