SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 8 ILE A  63
LEU A  68
GLU A  23
ALA A  24
VAL A  48
 None
None
MLY  A  26 ( 3.2A)
None
None
 1.26A 1a29A-1llnA:
undetectable		 1a29A-1llnA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1503_0
(FERROCHELATASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.46A 1hrkA-1llnA:
undetectable		 1hrkA-1llnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 7 GLU A 172
GLU A 203
ILE A 200
LEU A 164
 None
 1.38A 1q0yH-1llnA:
undetectable
1q0yL-1llnA:
0.0		 1q0yH-1llnA:
20.96
1q0yL-1llnA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.51A 2po5B-1llnA:
undetectable		 2po5B-1llnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.51A 2po7B-1llnA:
undetectable		 2po7B-1llnA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.32A 2qd5B-1llnA:
undetectable		 2qd5B-1llnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_B_SAMB298_1
(PUTATIVE
MODIFICATION
METHYLASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 ASP A 249
THR A  10
GLU A 180
 None
None
MLY  A 177 ( 3.3A)
 0.68A 2zifB-1llnA:
undetectable		 2zifB-1llnA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.47A 3hcrA-1llnA:
0.0		 3hcrA-1llnA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_A_ACHA323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.37A 3rqwA-1llnA:
0.0
3rqwB-1llnA:
0.0		 3rqwA-1llnA:
19.64
3rqwB-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_B_ACHB323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.36A 3rqwB-1llnA:
0.0
3rqwC-1llnA:
0.0		 3rqwB-1llnA:
19.64
3rqwC-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_D_ACHD323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.38A 3rqwD-1llnA:
0.0
3rqwE-1llnA:
0.0		 3rqwD-1llnA:
19.64
3rqwE-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_E_ACHE323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.37A 3rqwA-1llnA:
0.0
3rqwE-1llnA:
0.0		 3rqwA-1llnA:
19.64
3rqwE-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_F_ACHF323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.37A 3rqwF-1llnA:
0.0
3rqwG-1llnA:
0.0		 3rqwF-1llnA:
19.64
3rqwG-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_G_ACHG323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.37A 3rqwG-1llnA:
0.0
3rqwH-1llnA:
0.0		 3rqwG-1llnA:
19.64
3rqwH-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_H_ACHH323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 9 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.38A 3rqwH-1llnA:
0.0
3rqwI-1llnA:
0.0		 3rqwH-1llnA:
19.64
3rqwI-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 8 ILE A 111
GLU A 159
TYR A  73
LEU A  61
PHE A 162
 None
 1.36A 3rqwI-1llnA:
0.0
3rqwJ-1llnA:
0.0		 3rqwI-1llnA:
19.64
3rqwJ-1llnA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 LEU A 226
PRO A 227
LEU A 230
 None
None
MLY  A 231 ( 4.0A)
 0.36A 3w1wB-1llnA:
undetectable		 3w1wB-1llnA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 12 LEU A  70
ILE A  63
GLN A 168
ALA A 173
SER A 174
 None
 1.42A 4a83A-1llnA:
0.7		 4a83A-1llnA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CD2_A_FOLA207_0
(DIHYDROFOLATE
REDUCTASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 12 ILE A 144
ALA A 160
ILE A 165
PHE A 162
LEU A  52
 MLY  A 143 ( 3.9A)
None
None
None
MLY  A  53 ( 4.3A)
 1.25A 4cd2A-1llnA:
undetectable		 4cd2A-1llnA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M48_A_21BA704_1
(TRANSPORTER)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 8 ASP A 196
VAL A 183
TYR A 193
GLY A 131
ALA A 173
 MLY  A 198 ( 3.8A)
MLY  A 184 ( 3.1A)
MLY  A 182 ( 3.3A)
None
None
 1.45A 4m48A-1llnA:
undetectable		 4m48A-1llnA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_A_TFPA203_1
(CALMODULIN)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 8 ILE A  63
LEU A  68
ALA A  24
VAL A  48
 None
 0.63A 4rjdA-1llnA:
undetectable		 4rjdA-1llnA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RJD_B_TFPB204_1
(CALMODULIN)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 8 LEU A 130
GLY A 131
GLU A 203
ALA A 173
 None
 0.90A 4rjdA-1llnA:
undetectable
4rjdB-1llnA:
undetectable		 4rjdA-1llnA:
18.50
4rjdB-1llnA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 GLU A 172
ALA A 173
PHE A 176
 None
 0.54A 4v1fA-1llnA:
0.2		 4v1fA-1llnA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		3 / 3 GLU A 172
ALA A 173
PHE A 176
 None
 0.50A 4v1fC-1llnA:
0.2		 4v1fC-1llnA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 12 ALA A 149
LEU A  61
ILE A   2
LEU A 137
PHE A  59
 None
None
None
MLY  A 134 ( 4.8A)
None
 1.21A 5fsaA-1llnA:
undetectable		 5fsaA-1llnA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLC_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		5 / 12 ALA A  62
GLY A 192
PHE A 162
THR A 171
MET A 169
 None
None
None
None
MLY  A 134 ( 4.8A)
 1.26A 5jlcA-1llnA:
undetectable		 5jlcA-1llnA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.40A 5x7pA-1llnA:
0.0		 5x7pA-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.39A 5x7pB-1llnA:
0.0		 5x7pB-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.43A 5x7qA-1llnA:
0.0		 5x7qA-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.43A 5x7qB-1llnA:
0.0		 5x7qB-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.46A 5x7rA-1llnA:
0.0		 5x7rA-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 6 SER A 116
ARG A 127
GLU A 121
TYR A 117
 MLY  A 115 ( 4.2A)
None
None
None
 1.43A 5x7rB-1llnA:
0.0		 5x7rB-1llnA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 5 GLY A  66
ASN A  67
ARG A  65
ARG A  64
 None
None
None
MLY  A  46 ( 3.7A)
 1.16A 6dwdB-1llnA:
0.0
6dwdD-1llnA:
0.0		 6dwdB-1llnA:
18.63
6dwdD-1llnA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1lln ANTIVIRAL PROTEIN 3
(Phytolacca
americana) 		4 / 5 ARG A  65
ARG A  64
GLY A  66
ASN A  67
 None
MLY  A  46 ( 3.7A)
None
None
 1.19A 6dwjB-1llnA:
0.0
6dwjD-1llnA:
0.0		 6dwjB-1llnA:
18.63
6dwjD-1llnA:
18.63