SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1llu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 9 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.18A 1gtfD-1lluA:
undetectable
1gtfE-1lluA:
undetectable		 1gtfD-1lluA:
10.88
1gtfE-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		6 / 12 GLY A 239
ALA A 237
ILE A 254
PRO A 226
ILE A 200
ILE A 230
 None
 1.35A 1hshA-1lluA:
undetectable		 1hshA-1lluA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.77A 1muiB-1lluA:
undetectable		 1muiB-1lluA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.20A 1p6kB-1lluA:
0.0		 1p6kB-1lluA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.25A 1rs6B-1lluA:
0.0		 1rs6B-1lluA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  90
ALA A 132
THR A 118
HIS A  67
GLY A  66
 None
None
None
ZN  A 343 ( 3.3A)
None
 1.17A 1utdE-1lluA:
undetectable
1utdF-1lluA:
undetectable		 1utdE-1lluA:
10.88
1utdF-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.35A 1zzqB-1lluA:
undetectable		 1zzqB-1lluA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.35A 1zzuA-1lluA:
0.0		 1zzuA-1lluA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.23A 1zzuB-1lluA:
0.0		 1zzuB-1lluA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_2
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.85A 2aquB-1lluA:
undetectable		 2aquB-1lluA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.84A 2bpxB-1lluA:
undetectable		 2bpxB-1lluA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.77A 2fxeB-1lluA:
undetectable		 2fxeB-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLN A 115
ALA A  97
LEU A 131
ASP A 133
LEU A  94
 None
ZN  A 344 ( 4.6A)
None
None
None
 1.38A 2nv4B-1lluA:
undetectable		 2nv4B-1lluA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.87A 2o4kB-1lluA:
undetectable		 2o4kB-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.67A 2o4sA-1lluA:
undetectable		 2o4sA-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.80A 2q63A-1lluA:
undetectable		 2q63A-1lluA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.82A 2q64B-1lluA:
undetectable		 2q64B-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q9R_A_BEZA203_0
(PROTEIN OF UNKNOWN
FUNCTION)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 306
PRO A 141
ILE A 149
ILE A 152
 None
 0.86A 2q9rA-1lluA:
undetectable		 2q9rA-1lluA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  38
ALA A 127
GLY A  66
VAL A  43
GLY A  42
 None
 0.96A 2qe6B-1lluA:
5.0		 2qe6B-1lluA:
25.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.83A 2r5pB-1lluA:
undetectable		 2r5pB-1lluA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.83A 2r5pD-1lluA:
undetectable		 2r5pD-1lluA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.87A 2r5qB-1lluA:
undetectable		 2r5qB-1lluA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 132
PRO A 134
VAL A 137
PHE A 146
ASP A  87
 None
 1.34A 2v95A-1lluA:
0.0		 2v95A-1lluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V95_A_HCYA1375_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 132
PRO A 134
VAL A 137
PHE A 146
LYS A  37
 None
 1.22A 2v95A-1lluA:
0.0		 2v95A-1lluA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.81A 3bvbA-1lluA:
undetectable		 3bvbA-1lluA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 178
VAL A 185
ASP A 201
ILE A 202
ASP A 203
 NAD  A1250 (-3.6A)
None
NAD  A1250 (-2.9A)
NAD  A1250 (-4.1A)
None
 0.85A 3cjtC-1lluA:
9.9		 3cjtC-1lluA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1X_A_ROCA201_1
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.69A 3d1xA-1lluA:
undetectable		 3d1xA-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_1
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.80A 3d1yA-1lluA:
undetectable		 3d1yA-1lluA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.89A 3el1B-1lluA:
undetectable		 3el1B-1lluA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.93A 3em4U-1lluA:
undetectable		 3em4U-1lluA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 8 VAL A  83
ILE A 149
VAL A  70
GLY A 138
 None
 0.88A 3hjoB-1lluA:
0.0		 3hjoB-1lluA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.76A 3jvyB-1lluA:
undetectable		 3jvyB-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_2
(GAG-POL POLYPROTEIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.72A 3jw2B-1lluA:
undetectable		 3jw2B-1lluA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.81A 3k4vA-1lluA:
undetectable		 3k4vA-1lluA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.82A 3k4vB-1lluA:
undetectable		 3k4vB-1lluA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 312
THR A 313
ALA A 186
GLY A 183
ALA A 155
 None
 0.93A 3mg0K-1lluA:
undetectable
3mg0L-1lluA:
undetectable		 3mg0K-1lluA:
21.08
3mg0L-1lluA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.81A 3ndtA-1lluA:
undetectable		 3ndtA-1lluA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_3
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.78A 3ndtB-1lluA:
undetectable		 3ndtB-1lluA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.89A 3ndxB-1lluA:
undetectable		 3ndxB-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.84A 3nu3A-1lluA:
undetectable		 3nu3A-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.89A 3nu5A-1lluA:
undetectable		 3nu5A-1lluA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.76A 3oxcA-1lluA:
undetectable		 3oxcA-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_B_SAMB6735_0
(16S RRNA METHYLASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 162
VAL A 292
ALA A 186
THR A 243
LEU A 241
 None
NAD  A1250 ( 3.5A)
None
NAD  A1250 (-4.8A)
None
 1.12A 3p2kB-1lluA:
4.9		 3p2kB-1lluA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.88A 3tkgD-1lluA:
undetectable		 3tkgD-1lluA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.81A 3tkwB-1lluA:
undetectable		 3tkwB-1lluA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_1
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.83A 3tl9A-1lluA:
undetectable		 3tl9A-1lluA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.85A 3tl9B-1lluA:
undetectable		 3tl9B-1lluA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  91
GLY A  69
VAL A 122
THR A 118
GLY A 119
 None
 1.30A 4acaB-1lluA:
2.5
4acaC-1lluA:
3.1		 4acaB-1lluA:
21.79
4acaC-1lluA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 125
GLY A  66
ILE A  38
ASN A 123
VAL A 130
 None
 0.97A 4fr0A-1lluA:
5.6		 4fr0A-1lluA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 125
LEU A 153
ILE A  38
ASN A 123
VAL A 130
 None
 1.04A 4fr0A-1lluA:
5.6		 4fr0A-1lluA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 7 ILE A 234
ARG A 258
GLY A 261
ALA A 175
 None
 0.97A 4g0uB-1lluA:
undetectable		 4g0uB-1lluA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.81A 4jecA-1lluA:
undetectable		 4jecA-1lluA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		3 / 3 GLN A 172
HIS A 238
ARG A 258
 None
 1.02A 4qyqA-1lluA:
0.0		 4qyqA-1lluA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		3 / 3 GLN A 172
HIS A 238
ARG A 258
 None
 0.96A 4qyqB-1lluA:
undetectable		 4qyqB-1lluA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 8 ALA A 190
ILE A 230
THR A 243
VAL A 266
 None
None
NAD  A1250 (-4.8A)
NAD  A1250 (-3.6A)
 0.64A 4r20A-1lluA:
undetectable		 4r20A-1lluA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 156
ALA A 150
PHE A 304
VAL A 185
HIS A 184
 None
 1.14A 4rvdA-1lluA:
6.6		 4rvdA-1lluA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 156
ALA A 150
PHE A 304
VAL A 185
HIS A 184
 None
 1.14A 4rvgA-1lluA:
3.5		 4rvgA-1lluA:
26.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 SER A  41
LEU A 340
ILE A  21
ILE A  64
GLY A 124
 None
 1.00A 4y8wC-1lluA:
0.0		 4y8wC-1lluA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 7 MET A 329
HIS A  67
CYH A 154
GLY A  42
 NAD  A1250 ( 4.4A)
ZN  A 343 ( 3.3A)
ZN  A 343 ( 2.4A)
None
 1.14A 5a5zC-1lluA:
undetectable		 5a5zC-1lluA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5eevA-1lluA:
undetectable
5eevB-1lluA:
undetectable		 5eevA-1lluA:
10.88
5eevB-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5eewA-1lluA:
undetectable
5eewB-1lluA:
0.0		 5eewA-1lluA:
10.88
5eewB-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5eexA-1lluA:
undetectable
5eexB-1lluA:
undetectable		 5eexA-1lluA:
10.88
5eexB-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5eeyA-1lluA:
undetectable
5eeyB-1lluA:
undetectable		 5eeyA-1lluA:
10.88
5eeyB-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5eezA-1lluA:
undetectable
5eezB-1lluA:
undetectable		 5eezA-1lluA:
10.88
5eezB-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5ef0A-1lluA:
undetectable
5ef0B-1lluA:
undetectable		 5ef0A-1lluA:
10.88
5ef0B-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5ef1A-1lluA:
undetectable
5ef1B-1lluA:
undetectable		 5ef1A-1lluA:
10.88
5ef1B-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5ef2A-1lluA:
undetectable
5ef2B-1lluA:
undetectable		 5ef2A-1lluA:
10.88
5ef2B-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A  66
GLY A  90
ALA A 132
THR A 118
HIS A  67
 None
None
None
None
ZN  A 343 ( 3.3A)
 1.17A 5ef3A-1lluA:
undetectable
5ef3B-1lluA:
undetectable		 5ef3A-1lluA:
10.88
5ef3B-1lluA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 192
ASP A 303
PRO A 141
PHE A 304
GLY A 306
 None
 1.25A 5hfjE-1lluA:
2.3		 5hfjE-1lluA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQX_A_ROCA101_1
(PROTEASE E35D-SQV)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A  42
ILE A  64
GLY A 119
VAL A  36
ILE A  38
 None
 0.75A 5kqxA-1lluA:
undetectable		 5kqxA-1lluA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_H_BO2H306_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 312
THR A 313
ALA A 186
GLY A 183
ALA A 155
 None
 0.99A 5lf3H-1lluA:
undetectable
5lf3I-1lluA:
undetectable		 5lf3H-1lluA:
21.10
5lf3I-1lluA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF3_V_BO2V303_1
(PROTEASOME SUBUNIT
BETA TYPE-7
PROTEASOME SUBUNIT
BETA TYPE-3)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 10 ALA A 312
THR A 313
ALA A 186
GLY A 183
ALA A 155
 None
 0.98A 5lf3V-1lluA:
undetectable
5lf3W-1lluA:
undetectable		 5lf3V-1lluA:
21.10
5lf3W-1lluA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 312
THR A 313
ALA A 186
GLY A 183
ALA A 155
 None
 1.00A 5lf7H-1lluA:
undetectable
5lf7I-1lluA:
undetectable		 5lf7H-1lluA:
21.10
5lf7I-1lluA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 11 ALA A 312
THR A 313
ALA A 186
GLY A 183
ALA A 155
 None
 0.98A 5lf7V-1lluA:
undetectable
5lf7W-1lluA:
undetectable		 5lf7V-1lluA:
21.10
5lf7W-1lluA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 THR A  46
HIS A  49
ALA A  50
ASP A  47
 EDO  A1260 ( 2.9A)
NAD  A1250 (-3.9A)
None
None
 1.31A 5mfxA-1lluA:
2.2		 5mfxA-1lluA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 180
HIS A 184
VAL A 185
VAL A 187
VAL A 242
 NAD  A1250 (-3.4A)
None
None
None
None
 1.18A 5n0oA-1lluA:
1.3		 5n0oA-1lluA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 180
HIS A 184
VAL A 185
VAL A 187
VAL A 242
 NAD  A1250 (-3.4A)
None
None
None
None
 1.20A 5n0wA-1lluA:
2.2		 5n0wA-1lluA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 263
LEU A 285
VAL A 240
GLY A 239
GLY A 236
 None
 1.23A 5nnaA-1lluA:
undetectable		 5nnaA-1lluA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 263
LEU A 285
VAL A 240
GLY A 239
GLY A 236
 None
 1.24A 5nnaB-1lluA:
undetectable		 5nnaB-1lluA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 ILE A 263
LEU A 285
VAL A 240
GLY A 239
GLY A 236
 None
 1.22A 5nnaD-1lluA:
undetectable		 5nnaD-1lluA:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 137
ILE A  91
VAL A  34
ALA A 132
 None
 0.66A 5ospA-1lluA:
0.0		 5ospA-1lluA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 7 VAL A 137
ILE A  91
VAL A  34
ALA A 132
 None
 0.62A 5osrA-1lluA:
0.0		 5osrA-1lluA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		4 / 5 GLY A 251
GLN A 252
VAL A 242
SER A 246
 None
None
None
NAD  A1250 (-3.3A)
 1.23A 5vunA-1lluA:
0.0		 5vunA-1lluA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_A_SAMA601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.95A 5wz1A-1lluA:
4.6		 5wz1A-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_C_SAMC601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.97A 5wz1C-1lluA:
4.6		 5wz1C-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_D_SAMD601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.94A 5wz1D-1lluA:
4.8		 5wz1D-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_E_SAME601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.96A 5wz1E-1lluA:
4.6		 5wz1E-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_F_SAMF601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.94A 5wz1F-1lluA:
4.3		 5wz1F-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_G_SAMG601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.96A 5wz1G-1lluA:
4.5		 5wz1G-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_H_SAMH601_0
(NS5
METHYLTRANSFERASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.97A 5wz1H-1lluA:
4.6		 5wz1H-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 336
GLY A 156
GLY A 180
THR A 158
ILE A 152
 None
None
NAD  A1250 (-3.4A)
NAD  A1250 (-3.0A)
None
 0.92A 5wz2C-1lluA:
4.4		 5wz2C-1lluA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)		 1llu ALCOHOL
DEHYDROGENASE
(Pseudomonas
aeruginosa) 		7 / 12 VAL A 159
GLY A 178
GLY A 180
VAL A 185
ILE A 202
GLN A 252
ALA A 244
 None
NAD  A1250 (-3.6A)
NAD  A1250 (-3.4A)
None
NAD  A1250 (-4.1A)
None
NAD  A1250 (-3.4A)
 1.45A 5x7fA-1lluA:
8.6		 5x7fA-1lluA:
24.51