SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ6_A_CAMA502_0
(CYTOCHROME P450-CAM)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		4 / 5 TYR A   3
LEU A 127
VAL A  22
ASP A  17
 None
 1.49A 1dz6A-1lmiA:
undetectable		 1dz6A-1lmiA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_A_CAMA503_0
(CYTOCHROME P450-CAM)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		5 / 9 TYR A   3
LEU A 127
GLY A  25
VAL A  22
ASP A  17
 None
 1.45A 1dz8A-1lmiA:
undetectable		 1dz8A-1lmiA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ8_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		5 / 9 TYR A   3
LEU A 127
GLY A  25
VAL A  22
ASP A  17
 None
 1.42A 1dz8B-1lmiA:
0.0		 1dz8B-1lmiA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_B_CAMB502_0
(CYTOCHROME P450-CAM)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		5 / 9 TYR A   3
LEU A 127
GLY A  25
VAL A  22
ASP A  17
 None
 1.45A 1dz9B-1lmiA:
undetectable		 1dz9B-1lmiA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		5 / 9 ILE A  95
GLY A  98
GLU A  99
ALA A  56
THR A  94
 None
 1.29A 2dtjA-1lmiA:
undetectable
2dtjB-1lmiA:
undetectable		 2dtjA-1lmiA:
20.00
2dtjB-1lmiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1lmi IMMUNOGENIC PROTEIN
MPT63/MPB63
(Mycobacterium
tuberculosis) 		4 / 5 TYR A  41
ALA A  44
GLN A  46
THR A 110
 None
 1.37A 5n0tA-1lmiA:
undetectable		 5n0tA-1lmiA:
16.75