SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.38A 1os2A-1lmlA:
8.4		 1os2A-1lmlA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.44A 1os2D-1lmlA:
8.6		 1os2D-1lmlA:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 10 HIS A 264
GLU A 265
HIS A 268
HIS A 334
ALA A 348
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
None
 0.58A 1r55A-1lmlA:
6.9		 1r55A-1lmlA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 8 LEU A 118
ALA A 247
ILE A 250
HIS A 135
 None
 0.66A 1sv9A-1lmlA:
undetectable		 1sv9A-1lmlA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDN_A_LEUA487_0
(L-AMINO ACID OXIDASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 7 ARG A 102
PHE A 233
TYR A 368
ILE A 111
 None
 1.48A 1tdnA-1lmlA:
undetectable		 1tdnA-1lmlA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.42A 1uttA-1lmlA:
8.6		 1uttA-1lmlA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.43A 1utzA-1lmlA:
8.6		 1utzA-1lmlA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.45A 1utzB-1lmlA:
8.6		 1utzB-1lmlA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.44A 1y93A-1lmlA:
8.5		 1y93A-1lmlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 TRP A 380
ARG A 338
PHE A 388
 None
 1.27A 1zeaH-1lmlA:
undetectable
1zeaL-1lmlA:
undetectable		 1zeaH-1lmlA:
20.18
1zeaL-1lmlA:
15.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 2eimA-1lmlA:
undetectable		 2eimA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.43A 2hu6A-1lmlA:
8.4		 2hu6A-1lmlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 9 LEU A 224
HIS A 264
GLU A 265
HIS A 268
HIS A 334
 None
ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.93A 2jihA-1lmlA:
4.5		 2jihA-1lmlA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.34A 2ow9A-1lmlA:
8.6		 2ow9A-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.39A 2ow9B-1lmlA:
8.6		 2ow9B-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.35A 2ozrC-1lmlA:
8.6		 2ozrC-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.41A 2ozrD-1lmlA:
4.2		 2ozrD-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.47A 2ozrE-1lmlA:
8.4		 2ozrE-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 264
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.33A 2ozrF-1lmlA:
4.1		 2ozrF-1lmlA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 2y69A-1lmlA:
undetectable		 2y69A-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 2y69N-1lmlA:
0.0		 2y69N-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.79A 2zxwA-1lmlA:
undetectable		 2zxwA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 3abkN-1lmlA:
undetectable		 3abkN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 3abmA-1lmlA:
undetectable		 3abmA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.73A 3ag1A-1lmlA:
undetectable		 3ag1A-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 3ag1N-1lmlA:
undetectable		 3ag1N-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.76A 3asnN-1lmlA:
undetectable		 3asnN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 3bvdA-1lmlA:
undetectable		 3bvdA-1lmlA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.71A 3dtuA-1lmlA:
undetectable		 3dtuA-1lmlA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.73A 3dtuC-1lmlA:
undetectable		 3dtuC-1lmlA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 9 LEU A 224
HIS A 264
GLU A 265
HIS A 268
HIS A 334
 None
ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.92A 3hy7A-1lmlA:
6.8		 3hy7A-1lmlA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.37A 3kecA-1lmlA:
8.7		 3kecA-1lmlA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.39A 3likA-1lmlA:
8.3		 3likA-1lmlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.41A 3lilA-1lmlA:
8.6		 3lilA-1lmlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.44A 3ljgA-1lmlA:
8.3		 3ljgA-1lmlA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.43A 3lkaA-1lmlA:
8.6		 3lkaA-1lmlA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 3wg7A-1lmlA:
0.0		 3wg7A-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 3wg7N-1lmlA:
undetectable		 3wg7N-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.71A 3x2qN-1lmlA:
undetectable		 3x2qN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.31A 4a7bA-1lmlA:
8.6		 4a7bA-1lmlA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 THR A 229
GLY A 241
ILE A 243
LEU A 270
 None
 1.01A 4acbC-1lmlA:
undetectable		 4acbC-1lmlA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 12 ALA A 486
ILE A 490
SER A 523
VAL A 524
ILE A 556
 None
 0.97A 4ax8A-1lmlA:
undetectable		 4ax8A-1lmlA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 12 ALA A 486
ILE A 490
SER A 523
VAL A 524
ILE A 556
 None
 1.00A 4azvA-1lmlA:
undetectable		 4azvA-1lmlA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 VAL A 113
VAL A 214
ILE A 243
LEU A 270
 None
 0.94A 4l1wB-1lmlA:
undetectable		 4l1wB-1lmlA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 TYR A 254
ARG A 253
ASP A 154
VAL A 214
 None
 1.35A 4nkvB-1lmlA:
0.0		 4nkvB-1lmlA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P7N_A_GCSA702_1
(POLY-BETA-1,6-N-ACET
YL-D-GLUCOSAMINE
N-DEACETYLASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 ASP A 342
TYR A 353
TRP A 380
 None
 1.04A 4p7nA-1lmlA:
undetectable		 4p7nA-1lmlA:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_RTLC201_1
(RETINOL-BINDING
PROTEIN 2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 LYS A 336
TRP A 437
GLN A 325
 None
 1.47A 4qzuC-1lmlA:
0.0		 4qzuC-1lmlA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 12 GLY A 352
GLY A 567
ASN A 568
ALA A 346
ALA A 350
 None
 0.96A 4uciA-1lmlA:
undetectable		 4uciA-1lmlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 12 GLY A 352
GLY A 567
ASN A 568
ALA A 346
ALA A 350
 None
 0.96A 4uciB-1lmlA:
undetectable		 4uciB-1lmlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.41A 4w5qA-1lmlA:
0.0		 4w5qA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.42A 4w5tA-1lmlA:
0.0		 4w5tA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3U_B_SVRB102_1
(CHROMOBOX PROTEIN
HOMOLOG 7)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 LYS A 152
ARG A 127
VAL A 128
 None
 1.00A 4x3uA-1lmlA:
undetectable
4x3uB-1lmlA:
undetectable		 4x3uA-1lmlA:
10.71
4x3uB-1lmlA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 LEU A 365
ALA A 360
VAL A 322
ILE A 335
 None
 0.95A 4xe3B-1lmlA:
undetectable		 4xe3B-1lmlA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 LEU A 389
TYR A 312
ALA A 340
ILE A 335
 None
 1.16A 4y03B-1lmlA:
undetectable		 4y03B-1lmlA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.43A 4z4cA-1lmlA:
4.1		 4z4cA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.41A 4z4fA-1lmlA:
0.0		 4z4fA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.44A 4z4gA-1lmlA:
0.0		 4z4gA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.44A 4z4hA-1lmlA:
0.0		 4z4hA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ASP A 342
ALA A 340
THR A 355
TYR A 353
 None
 1.42A 4z4iA-1lmlA:
2.5		 4z4iA-1lmlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA401_0
(PROTON-GATED ION
CHANNEL)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ILE A 361
PHE A 272
ILE A 335
GLU A 343
 None
 1.40A 4zzcA-1lmlA:
undetectable
4zzcB-1lmlA:
undetectable		 4zzcA-1lmlA:
20.44
4zzcB-1lmlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB401_0
(PROTON-GATED ION
CHANNEL)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 6 ILE A 361
PHE A 272
ILE A 335
GLU A 343
 None
 1.36A 4zzcB-1lmlA:
0.0
4zzcC-1lmlA:
undetectable		 4zzcB-1lmlA:
20.44
4zzcC-1lmlA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.72A 5b1bA-1lmlA:
undetectable		 5b1bA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 5b1bN-1lmlA:
undetectable		 5b1bN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 5b3sA-1lmlA:
undetectable		 5b3sA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 5b3sN-1lmlA:
undetectable		 5b3sN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 VAL A 177
VAL A 174
GLY A 107
ARG A 110
 None
 1.00A 5d4nA-1lmlA:
0.0
5d4nC-1lmlA:
0.0		 5d4nA-1lmlA:
10.83
5d4nC-1lmlA:
10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_2
(CYP51 VARIANT1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 PRO A 460
ILE A 335
SER A 462
 None
 0.73A 5fsaA-1lmlA:
undetectable		 5fsaA-1lmlA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.73A 5iy5A-1lmlA:
0.0		 5iy5A-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 5iy5N-1lmlA:
undetectable		 5iy5N-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 527
ASN A 481
ALA A 473
 None
 0.80A 5n4tB-1lmlA:
undetectable		 5n4tB-1lmlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 4 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.43A 5n5jA-1lmlA:
8.6		 5n5jA-1lmlA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 5 HIS A 264
GLU A 265
HIS A 268
HIS A 334
 ZN  A 578 ( 3.5A)
ZN  A 578 ( 4.1A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
 0.43A 5n5kA-1lmlA:
8.6		 5n5kA-1lmlA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 8 GLY A 554
LEU A 543
VAL A 546
ILE A 556
GLY A 492
 None
 1.26A 5vkqB-1lmlA:
undetectable
5vkqC-1lmlA:
undetectable		 5vkqB-1lmlA:
14.02
5vkqC-1lmlA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		5 / 12 ALA A 225
LEU A 156
ILE A 155
VAL A 258
TYR A 254
 None
 1.46A 5vlmE-1lmlA:
0.0		 5vlmE-1lmlA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.70A 5w97a-1lmlA:
0.0		 5w97a-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 5waua-1lmlA:
0.0		 5waua-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 5x19A-1lmlA:
undetectable		 5x19A-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.70A 5x19N-1lmlA:
undetectable		 5x19N-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.68A 5x1bA-1lmlA:
0.0		 5x1bA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.65A 5x1bN-1lmlA:
undetectable		 5x1bN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.72A 5x1fA-1lmlA:
undetectable		 5x1fA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.64A 5x1fN-1lmlA:
0.0		 5x1fN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.75A 5xdqA-1lmlA:
undetectable		 5xdqA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.76A 5xdqN-1lmlA:
0.0		 5xdqN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.71A 5xdxA-1lmlA:
undetectable		 5xdxA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.71A 5xdxN-1lmlA:
0.0		 5xdxN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BTX_A_EDTA503_0
(SOLUTE CARRIER
FAMILY 39
(IRON-REGULATED
TRANSPORTER))		 1lml LEISHMANOLYSIN
(Leishmania
major) 		4 / 7 SER A 418
SER A 421
GLY A 423
LEU A 257
 None
 1.15A 6btxA-1lmlA:
0.0		 6btxA-1lmlA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.70A 6hu9a-1lmlA:
undetectable		 6hu9a-1lmlA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 6hu9m-1lmlA:
undetectable		 6hu9m-1lmlA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.76A 6nknA-1lmlA:
undetectable		 6nknA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.76A 6nknN-1lmlA:
0.0		 6nknN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.69A 6nmfA-1lmlA:
0.0		 6nmfA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.69A 6nmfN-1lmlA:
0.0		 6nmfN-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.74A 6nmpA-1lmlA:
undetectable		 6nmpA-1lmlA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lml LEISHMANOLYSIN
(Leishmania
major) 		3 / 3 HIS A 334
HIS A 268
HIS A 264
 ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.4A)
ZN  A 578 ( 3.5A)
 0.76A 6nmpN-1lmlA:
0.0		 6nmpN-1lmlA:
19.60