SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ln1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		5 / 12 ILE A  71
PHE A 199
LEU A 200
MET A 203
MET A 173
 None
DLP  A2313 (-3.4A)
None
DLP  A2313 (-4.2A)
DLP  A2313 (-4.2A)
 1.09A 1dtlA-1ln1A:
undetectable		 1dtlA-1ln1A:
24.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		5 / 12 MET A 203
ILE A  41
LEU A  60
LEU A  68
TYR A  72
 DLP  A2313 (-4.2A)
DLP  A2313 (-3.2A)
None
None
DLP  A2313 (-4.4A)
 1.29A 2mjiA-1ln1A:
1.7		 2mjiA-1ln1A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 121
ASP A 122
ARG A 120
 None
 0.59A 4wq4B-1ln1A:
0.0		 4wq4B-1ln1A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  99
THR A  97
ARG A 118
 None
 0.63A 5b2sB-1ln1A:
undetectable		 5b2sB-1ln1A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  99
THR A  97
ARG A 118
 None
 0.66A 5b2tB-1ln1A:
undetectable		 5b2tB-1ln1A:
9.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1ln1 PHOSPHATIDYLCHOLINE
TRANSFER PROTEIN
(Homo
sapiens) 		4 / 7 VAL A 132
LEU A 134
ALA A 160
LEU A 123
 None
 0.62A 5jq7A-1ln1A:
0.0		 5jq7A-1ln1A:
18.75