SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		5 / 11 CYH A 121
LEU A 142
ILE A 207
ILE A 182
VAL A 183
 None
 1.22A 1pkvA-1lnqA:
undetectable
1pkvB-1lnqA:
undetectable		 1pkvA-1lnqA:
15.53
1pkvB-1lnqA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		5 / 8 ALA A 178
ILE A 198
ILE A 207
ILE A 120
PRO A 164
 None
 1.12A 1sh9A-1lnqA:
undetectable		 1sh9A-1lnqA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA142_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A 326
PRO A 324
ILE A 327
GLY A 322
 None
 1.12A 2qeuA-1lnqA:
undetectable
2qeuC-1lnqA:
undetectable		 2qeuA-1lnqA:
16.67
2qeuC-1lnqA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NY4_A_SMXA310_1
(BETA-LACTAMASE)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 LEU A 185
THR A 127
GLY A 162
PRO A 164
 None
 0.71A 3ny4A-1lnqA:
undetectable		 3ny4A-1lnqA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		4 / 8 VAL A 278
LEU A 275
TYR A 333
VAL A 291
 None
 0.97A 4ma7A-1lnqA:
2.1		 4ma7A-1lnqA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_F_MFXF2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		4 / 6 ASP A 316
ARG A 298
GLY A 299
GLU A 301
 None
 1.08A 5cdqA-1lnqA:
0.0
5cdqC-1lnqA:
0.0
5cdqD-1lnqA:
3.2		 5cdqA-1lnqA:
22.22
5cdqC-1lnqA:
22.22
5cdqD-1lnqA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_B_ADNB401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 1lnq POTASSIUM CHANNEL
RELATED PROTEIN
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 GLY A 122
ASP A 145
VAL A 148
ASP A 163
LEU A 185
 None
 1.08A 6bq4B-1lnqA:
5.7		 6bq4B-1lnqA:
14.84