SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lnz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A27_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 VAL A 161
GLY A 162
LEU A 163
VAL A 178
PHE A 208
None
1.47A 1a27A-1lnzA:
undetectable
1a27A-1lnzA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4001_1
(SERUM ALBUMIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 5 LYS A  65
ALA A  66
ASP A  14
GLY A 119
None
1.15A 1e7cA-1lnzA:
undetectable
1e7cA-1lnzA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FIQ_C_SALC1335_1
(XANTHINE OXIDASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 8 LEU A 321
PHE A 208
VAL A 241
LEU A 163
None
0.90A 1fiqC-1lnzA:
undetectable
1fiqC-1lnzA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 7 ILE A 261
HIS A 221
GLU A 218
LEU A 270
None
1.07A 1j96B-1lnzA:
2.5
1j96B-1lnzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KB9_A_PCFA514_0
(CYTOCHROME B
CYTOCHROME C1, HEME
PROTEIN
UBIQUINOL-CYTOCHROME
C REDUCTASE COMPLEX
CORE PROTEIN I
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 8 ILE A 185
VAL A 209
MET A 199
SER A 179
None
1.17A 1kb9A-1lnzA:
undetectable
1kb9C-1lnzA:
undetectable
1kb9D-1lnzA:
0.0
1kb9E-1lnzA:
0.0
1kb9A-1lnzA:
21.57
1kb9C-1lnzA:
18.95
1kb9D-1lnzA:
22.91
1kb9E-1lnzA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 11 ILE A 261
HIS A 221
GLU A 218
LEU A 270
LEU A 272
None
1.29A 1mrqA-1lnzA:
2.5
1mrqA-1lnzA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
3 / 3 LEU A 321
VAL A 324
LEU A 328
None
0.48A 1mz9B-1lnzA:
undetectable
1mz9B-1lnzA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
3 / 3 LEU A 231
HIS A 221
ILE A 217
None
0.64A 1s9pB-1lnzA:
0.0
1s9pB-1lnzA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  35
GLY A 125
GLY A  18
GLY A  36
GLY A  38
None
0.91A 3bogA-1lnzA:
0.0
3bogC-1lnzA:
0.0
3bogA-1lnzA:
undetectable
3bogC-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  38
GLY A 122
GLY A  15
GLY A  39
GLY A  41
None
0.88A 3bogA-1lnzA:
0.0
3bogC-1lnzA:
0.0
3bogA-1lnzA:
undetectable
3bogC-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  12
GLY A 119
GLY A  41
GLY A 146
None
0.62A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  15
GLY A  13
GLY A  42
GLY A 120
None
0.67A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  15
GLY A 122
GLY A  38
GLY A 143
None
0.61A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  18
GLY A  38
GLY A  16
GLY A  72
None
0.58A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  38
GLY A  16
GLY A  69
GLY A 122
None
0.66A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  38
GLY A  72
GLY A  36
GLY A  79
None
0.60A 3bogC-1lnzA:
0.0
3bogC-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  15
GLY A 143
GLY A 123
GLY A  16
GLY A  18
None
0.92A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  35
GLY A 125
GLY A  18
GLY A  36
GLY A  38
None
0.86A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  38
GLY A  16
GLY A  69
GLY A 122
GLY A  41
None
0.81A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  38
GLY A  18
GLY A 125
GLY A  72
GLY A  35
None
0.92A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  38
GLY A 122
GLY A  15
GLY A  39
GLY A  41
None
0.84A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  41
GLY A  15
GLY A 122
GLY A  69
GLY A  38
None
0.88A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A  69
GLY A  39
GLY A  38
GLY A  15
GLY A 123
None
0.88A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A 119
GLY A  13
GLY A  15
GLY A  42
GLY A  69
None
0.87A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 6 GLY A 123
GLY A 122
GLY A  15
GLY A  38
GLY A  69
None
0.86A 3bogB-1lnzA:
0.0
3bogD-1lnzA:
0.0
3bogB-1lnzA:
undetectable
3bogD-1lnzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  12
GLY A 119
GLY A  41
GLY A 146
None
0.62A 3bogD-1lnzA:
0.0
3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  18
GLY A  38
GLY A  16
GLY A  72
None
0.63A 3bogD-1lnzA:
0.0
3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A  38
GLY A  72
GLY A  36
GLY A  79
None
0.68A 3bogD-1lnzA:
0.0
3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD47_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A 120
GLY A  15
GLY A  39
GLY A  41
None
0.61A 3bogD-1lnzA:
0.0
3bogD-1lnzA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A 146
GLY A 123
GLY A  16
GLY A  41
PHE A 129
None
0.83A 3eluA-1lnzA:
undetectable
3eluA-1lnzA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A 146
GLY A 123
GLY A  16
GLY A  41
PHE A 129
None
0.88A 3elwA-1lnzA:
undetectable
3elwA-1lnzA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 10 ILE A 234
ASN A 269
TYR A 268
ILE A 217
GLU A 218
None
1.40A 3u6tA-1lnzA:
undetectable
3u6tA-1lnzA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 7 GLY A 123
GLY A 122
ASN A  81
GLU A 141
None
1.10A 4fgkB-1lnzA:
3.4
4fgkB-1lnzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A  41
GLY A 119
ARG A 121
ILE A  67
ALA A  66
None
1.00A 4kicA-1lnzA:
undetectable
4kicA-1lnzA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1X_B_STRB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 9 ILE A 261
HIS A 221
GLU A 218
LEU A 270
LEU A 272
None
1.28A 4l1xB-1lnzA:
2.5
4l1xB-1lnzA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A  41
GLY A  16
GLY A 123
ALA A  66
ALA A  82
None
0.95A 4uciA-1lnzA:
undetectable
4uciA-1lnzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A  41
GLY A  16
GLY A 123
ALA A  66
ALA A  82
None
0.95A 4uciB-1lnzA:
undetectable
4uciB-1lnzA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A  41
GLY A  16
GLY A 123
ALA A  66
ALA A  82
None
0.95A 4uckA-1lnzA:
undetectable
4uckA-1lnzA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 4 GLY A 165
LEU A 320
PHE A 307
ILE A 278
None
0.86A 4xv2A-1lnzA:
undetectable
4xv2A-1lnzA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 6 GLU A 144
GLY A 146
GLY A  13
ASP A  14
None
0.97A 5a06D-1lnzA:
3.4
5a06D-1lnzA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 10 LEU A 158
ALA A 159
LEU A 197
GLY A 215
LEU A 213
None
1.36A 5dx3A-1lnzA:
undetectable
5dx3A-1lnzA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
6 / 12 VAL A 241
HIS A 242
GLU A 264
VAL A 161
LEU A 216
GLY A 215
None
1.48A 5igtA-1lnzA:
0.0
5igtA-1lnzA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 ILE A 217
HIS A 221
GLY A 219
GLU A 274
ALA A 211
None
1.10A 5igyA-1lnzA:
undetectable
5igyA-1lnzA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 8 GLU A 148
PRO A 145
GLY A  13
ASP A  14
None
1.11A 5kgpA-1lnzA:
0.0
5kgpA-1lnzA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 8 GLU A 148
PRO A 145
GLY A  13
ASP A  14
None
1.09A 5kgpB-1lnzA:
0.0
5kgpB-1lnzA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 9 ILE A 261
VAL A 169
ASP A 256
ILE A 244
None
1.04A 5lg3I-1lnzA:
undetectable
5lg3I-1lnzA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
4 / 6 VAL A 280
LEU A 163
LEU A 272
GLU A 264
None
0.97A 5tudD-1lnzA:
undetectable
5tudD-1lnzA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
3 / 3 ARG A  53
PHE A   2
LEU A 155
None
0.80A 5veuA-1lnzA:
undetectable
5veuA-1lnzA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_0
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 GLY A  79
GLY A  41
GLY A  16
ALA A  66
ALA A  82
None
0.84A 5x7fA-1lnzA:
undetectable
5x7fA-1lnzA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 7 GLY A 119
GLY A  13
GLY A  15
GLY A  38
GLY A  39
None
1.04A 6ag0A-1lnzA:
undetectable
6ag0A-1lnzA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA606_0
(ALPHA-AMYLASE)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 7 GLY A 119
GLY A 120
GLY A 122
GLY A  38
GLY A  16
None
1.04A 6ag0A-1lnzA:
undetectable
6ag0A-1lnzA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)
1lnz SPO0B-ASSOCIATED
GTP-BINDING PROTEIN

(Bacillus
subtilis)
5 / 12 LEU A 300
GLN A 277
LEU A 163
ILE A 261
ASP A 257
None
1.15A 6bxmA-1lnzA:
2.1
6bxmA-1lnzA:
23.78