SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lo4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 1lo4 IG GAMMA 2A HEAVY
CHAIN
(Mus
musculus) 		5 / 10 TRP H  47
SER H  50
TYR H  58
GLY H  98
TRP H 108
 None
 0.92A 3ls4H-1lo4H:
28.3		 3ls4H-1lo4H:
79.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA501_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1lo4 IG GAMMA 2A HEAVY
CHAIN
(Mus
musculus) 		4 / 5 TYR H  93
LEU H  80
LEU H  85
ARG H  66
 None
 1.28A 4em2A-1lo4H:
undetectable		 4em2A-1lo4H:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1lo4 IG GAMMA 2A HEAVY
CHAIN
(Mus
musculus) 		4 / 7 ALA H  91
THR H  90
VAL H 114
GLU H  88
 None
 0.71A 5ecmD-1lo4H:
0.0		 5ecmD-1lo4H:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1lo4 IG GAMMA 2A HEAVY
CHAIN
(Mus
musculus) 		4 / 7 ALA H  91
THR H  90
VAL H 114
GLU H  88
 None
 0.79A 5ecoD-1lo4H:
0.0		 5ecoD-1lo4H:
19.58