SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lpl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 1lpl HYPOTHETICAL 25.4
KDA PROTEIN F53F4.3
IN CHROMOSOME V
(Caenorhabditis
elegans) 		4 / 6 CYH A 203
GLU A 165
GLY A 164
ASP A 185
 None
 1.02A 5a06D-1lplA:
undetectable		 5a06D-1lplA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 1lpl HYPOTHETICAL 25.4
KDA PROTEIN F53F4.3
IN CHROMOSOME V
(Caenorhabditis
elegans) 		3 / 3 GLY A 208
ASN A 191
ARG A 199
 None
 0.78A 5w7bD-1lplA:
undetectable		 5w7bD-1lplA:
16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lpl HYPOTHETICAL 25.4
KDA PROTEIN F53F4.3
IN CHROMOSOME V
(Caenorhabditis
elegans) 		4 / 5 TYR A 184
TYR A 207
GLY A 208
GLY A 209
 None
 0.73A 5x7pA-1lplA:
undetectable		 5x7pA-1lplA:
5.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1lpl HYPOTHETICAL 25.4
KDA PROTEIN F53F4.3
IN CHROMOSOME V
(Caenorhabditis
elegans) 		4 / 6 TYR A 184
TYR A 207
GLY A 208
GLY A 209
 None
 0.71A 5x7pB-1lplA:
undetectable		 5x7pB-1lplA:
5.12