SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lr0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M9Q_B_BEZB251_0
(SERINE PROTEASE
INHIBITOR
SERINE PROTEASE
SUBUNIT NS2B, SERINE
PROTEASE NS3)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		5 / 9 ILE A  58
ILE A  66
PHE A 116
VAL A  91
ALA A  86
 None
 1.13A 2m9qA-1lr0A:
undetectable		 2m9qA-1lr0A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O02_A_BEZA801_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 105
MET A  97
GLN A  98
ARG A 102
 None
 1.37A 2o02A-1lr0A:
undetectable		 2o02A-1lr0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 9 ILE A  58
PHE A 116
ALA A  84
VAL A  88
 None
 0.87A 2vufA-1lr0A:
undetectable		 2vufA-1lr0A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 5 GLY A  28
ASP A  31
GLU A  96
VAL A  91
 None
 1.10A 4nkvD-1lr0A:
undetectable		 4nkvD-1lr0A:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 105
MET A  97
GLN A  98
ARG A 102
 None
 1.35A 5ewzA-1lr0A:
undetectable		 5ewzA-1lr0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		3 / 3 MET A  97
GLN A  98
ARG A 102
 None
 1.01A 5ewzB-1lr0A:
undetectable		 5ewzB-1lr0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J31_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 105
MET A  97
GLN A  98
ARG A 102
 None
 1.34A 5j31B-1lr0A:
1.9		 5j31B-1lr0A:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 105
MET A  97
GLN A  98
ARG A 102
 None
 1.33A 5m36B-1lr0A:
undetectable		 5m36B-1lr0A:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M37_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1lr0 TOLA PROTEIN
(Pseudomonas
aeruginosa) 		4 / 4 PHE A 105
MET A  97
GLN A  98
ARG A 102
 None
 1.30A 5m37A-1lr0A:
undetectable		 5m37A-1lr0A:
20.18