SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lrh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		4 / 4 ALA A 142
VAL A 144
ALA A 143
HIS A 140
 None
 0.98A 1q23A-1lrhA:
0.0		 1q23A-1lrhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		4 / 4 ALA A 142
VAL A 144
ALA A 143
HIS A 140
 None
 0.99A 1q23K-1lrhA:
0.0		 1q23K-1lrhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		4 / 6 GLN A  46
HIS A  57
HIS A  59
HIS A 106
 NLA  A5190 (-3.1A)
ZN  A 180 ( 3.4A)
ZN  A 180 ( 3.5A)
ZN  A 180 (-3.3A)
 1.10A 3nvcA-1lrhA:
10.6		 3nvcA-1lrhA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		4 / 6 GLN A  46
HIS A  59
HIS A 106
HIS A  57
 NLA  A5190 (-3.1A)
ZN  A 180 ( 3.5A)
ZN  A 180 (-3.3A)
ZN  A 180 ( 3.4A)
 1.16A 3nvcA-1lrhA:
10.6		 3nvcA-1lrhA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		5 / 12 THR A  54
VAL A 121
ALA A 128
CYH A  61
HIS A  59
 NLA  A5190 (-4.2A)
None
None
None
ZN  A 180 ( 3.5A)
 1.30A 3u9fD-1lrhA:
0.0
3u9fE-1lrhA:
0.0		 3u9fD-1lrhA:
18.92
3u9fE-1lrhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_G_CLMG221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		5 / 12 THR A  54
VAL A 121
ALA A 128
CYH A  61
HIS A  59
 NLA  A5190 (-4.2A)
None
None
None
ZN  A 180 ( 3.5A)
 1.24A 3u9fG-1lrhA:
0.0
3u9fH-1lrhA:
0.0		 3u9fG-1lrhA:
18.92
3u9fH-1lrhA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 1lrh AUXIN-BINDING
PROTEIN 1
(Zea
mays) 		3 / 3 HIS A  59
HIS A 106
HIS A  57
 ZN  A 180 ( 3.5A)
ZN  A 180 (-3.3A)
ZN  A 180 ( 3.4A)
 0.76A 6giqa-1lrhA:
undetectable		 6giqa-1lrhA:
14.71