SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A 122
PHE A  77
PRO A  79
THR A  81
 None
 1.40A 2q6oB-1lryA:
undetectable		 2q6oB-1lryA:
23.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  62
GLU A 134
ILE A 131
 None
BB2  A 170 (-2.6A)
None
 0.59A 3czhA-1lryA:
0.0		 3czhA-1lryA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		3 / 3 HIS A 133
GLU A 134
HIS A 137
 ZN  A 168 ( 3.4A)
BB2  A 170 (-2.6A)
ZN  A 168 ( 3.5A)
 0.19A 3kecB-1lryA:
undetectable		 3kecB-1lryA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A  55
LYS A  18
PRO A  19
 None
 1.28A 4dv1L-1lryA:
0.1		 4dv1L-1lryA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 143
VAL A 144
HIS A 137
ALA A  47
 None
None
ZN  A 168 ( 3.5A)
None
 0.92A 4eyzA-1lryA:
undetectable		 4eyzA-1lryA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		4 / 8 PHE A 143
VAL A 144
HIS A 137
ALA A  47
 None
None
ZN  A 168 ( 3.5A)
None
 0.92A 4eyzB-1lryA:
undetectable		 4eyzB-1lryA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1lry PEPTIDE DEFORMYLASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A  33
VAL A  51
LEU A  46
 None
 0.61A 5e5jB-1lryA:
undetectable		 5e5jB-1lryA:
19.88