SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ltt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.72A 2c8aA-1lttA:
undetectable		 2c8aA-1lttA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.65A 2c8aB-1lttA:
undetectable		 2c8aB-1lttA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 6 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.69A 2c8aC-1lttA:
undetectable		 2c8aC-1lttA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 7 ARG A   7
SER A  61
SER A  63
GLU A 112
 None
 0.72A 2c8aD-1lttA:
undetectable		 2c8aD-1lttA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		5 / 9 SER A  19
SER A  10
GLY A 126
ILE A  88
PHE A  52
 None
 1.33A 2dr6A-1lttA:
0.0		 2dr6A-1lttA:
10.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJG_B_ADNB1502_1
(235AA LONG
HYPOTHETICAL
BIOTIN--[ACETYL-COA-
CARBOXYLASE] LIGASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 7 ARG A 163
GLU A 159
PRO A 157
ALA A 156
 None
 1.45A 2ejgB-1lttA:
undetectable		 2ejgB-1lttA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		3 / 3 HIS A  27
MET A  23
MET A  37
 None
 1.32A 2vj1A-1lttA:
0.0		 2vj1A-1lttA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_B_VK3B202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 6 ASN A  93
TYR A 149
TYR A 150
LEU A 153
 None
 1.25A 4f8yA-1lttA:
undetectable
4f8yB-1lttA:
undetectable		 4f8yA-1lttA:
18.72
4f8yB-1lttA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 7 TYR A 149
TYR A 150
LEU A 153
ASN A  93
 None
 1.22A 4f8yC-1lttA:
undetectable
4f8yD-1lttA:
undetectable		 4f8yC-1lttA:
18.72
4f8yD-1lttA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 5 TYR A  59
LEU A   5
ASP A  99
GLU A 112
 None
 1.27A 4nkvA-1lttA:
undetectable		 4nkvA-1lttA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 1ltt HEAT-LABILE
ENTEROTOXIN, SUBUNIT
A
(Escherichia
coli) 		4 / 8 ARG A 146
TYR A 121
ILE A  16
GLY A 118
 None
 0.91A 5nooD-1lttA:
undetectable		 5nooD-1lttA:
18.73