SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lu2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ISM_B_NCAB305_0
(BONE MARROW STROMAL
CELL ANTIGEN 1)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 7 HIS A 138
LEU A 127
SER A 128
ASP A 133
 MN  A 302 (-3.7A)
A2G  A 254 ( 4.6A)
None
CA  A 301 ( 3.0A)
 1.29A 1ismB-1lu2A:
undetectable		 1ismB-1lu2A:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 6 LEU A 165
ALA A  68
SER A 228
SER A   7
 None
 0.53A 1tz8C-1lu2A:
undetectable
1tz8D-1lu2A:
undetectable		 1tz8C-1lu2A:
20.95
1tz8D-1lu2A:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1lu2 LECTIN
(Vigna
unguiculata) 		5 / 10 LEU A 179
ILE A 164
VAL A 122
ALA A 121
LEU A 105
 None
 1.15A 1xp0A-1lu2A:
undetectable		 1xp0A-1lu2A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 5 ARG A  99
PHE A 108
LEU A 200
ALA A 117
 None
 1.24A 2e1qD-1lu2A:
0.0		 2e1qD-1lu2A:
11.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 6 LEU A 214
GLU A 220
ILE A 219
PRO A  42
 A2G  A 254 (-4.1A)
None
None
None
 0.90A 2fcnA-1lu2A:
undetectable
2fcnB-1lu2A:
0.0		 2fcnA-1lu2A:
14.68
2fcnB-1lu2A:
14.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 8 HIS A 181
ILE A  75
TRP A 154
PHE A 124
 None
 1.39A 3ccfB-1lu2A:
undetectable		 3ccfB-1lu2A:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_G_SAMG302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1lu2 LECTIN
(Vigna
unguiculata) 		5 / 12 SER A 228
VAL A 252
LEU A 248
ILE A   3
LEU A 242
 None
 1.16A 3cjtG-1lu2A:
undetectable		 3cjtG-1lu2A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_K_SAMK302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1lu2 LECTIN
(Vigna
unguiculata) 		5 / 12 SER A 228
VAL A 252
LEU A 248
ILE A   3
LEU A 242
 None
 1.16A 3cjtK-1lu2A:
undetectable		 3cjtK-1lu2A:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA279_0
(UNIVERSAL STRESS
PROTEIN)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 4 SER A 226
SER A  70
THR A  69
SER A 228
 None
 1.13A 3loqA-1lu2A:
0.0		 3loqA-1lu2A:
25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODJ_A_SAMA500_0
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 7 HIS A 138
PRO A 134
SER A  82
ASP A 133
 MN  A 302 (-3.7A)
None
None
CA  A 301 ( 3.0A)
 1.32A 4odjA-1lu2A:
undetectable		 4odjA-1lu2A:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lu2 LECTIN
(Vigna
unguiculata) 		4 / 9 SER A  76
ALA A  77
LEU A 156
ILE A  87
 None
 0.88A 4xtaA-1lu2A:
undetectable		 4xtaA-1lu2A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN1_B_LLLB302_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE)		 1lu2 LECTIN
(Vigna
unguiculata) 		5 / 10 ASP A  85
GLY A 102
ASP A 223
THR A 221
SER A 209
 A2G  A 254 (-2.7A)
A2G  A 254 (-3.7A)
None
None
None
 1.46A 6mn1B-1lu2A:
0.0		 6mn1B-1lu2A:
16.16