SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lu4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AL4_A_DVAA8_0
(GRAMICIDIN D)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 5 VAL A1059
TRP A1030
VAL A1028
TRP A1032
 None
 1.37A 1al4A-1lu4A:
undetectable
1al4B-1lu4A:
undetectable		 1al4A-1lu4A:
6.47
1al4B-1lu4A:
6.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 12 LEU A1127
GLY A1129
ALA A1132
ASN A1053
SER A1047
 None
 1.16A 1dfoA-1lu4A:
undetectable		 1dfoA-1lu4A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 12 LEU A1127
GLY A1129
ALA A1132
ASN A1053
SER A1047
 None
 1.15A 1dfoB-1lu4A:
undetectable		 1dfoB-1lu4A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 12 LEU A1127
GLY A1129
ALA A1132
ASN A1053
SER A1047
 None
 1.16A 1dfoC-1lu4A:
undetectable		 1dfoC-1lu4A:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 11 LEU A1084
GLY A1019
TYR A1095
ILE A1091
ARG A1094
 None
 1.23A 1tmxA-1lu4A:
undetectable		 1tmxA-1lu4A:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_C_DX2C270_1
(PTERIDINE REDUCTASE
1)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 8 SER A1021
VAL A1028
LEU A1134
PRO A1026
 None
 1.00A 3jq7C-1lu4A:
undetectable		 3jq7C-1lu4A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 10 PHE A1031
TYR A1095
LEU A1005
GLY A1019
ILE A1061
 None
 1.12A 4jx1B-1lu4A:
undetectable		 4jx1B-1lu4A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_A_RBFA402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 8 LEU A1029
VAL A1131
LEU A1134
GLY A1110
 None
 0.74A 4r3aA-1lu4A:
undetectable		 4r3aA-1lu4A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 7 ASN A1040
PRO A1037
PHE A1038
PHE A1103
 None
 1.39A 4v32A-1lu4A:
0.0		 4v32A-1lu4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 7 ASN A1040
PRO A1037
PHE A1038
PHE A1103
 None
 1.39A 4v32B-1lu4A:
0.0		 4v32B-1lu4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V32_C_EF2C151_1
(CEREBLON ISOFORM 4)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 7 ASN A1040
PRO A1037
PHE A1038
PHE A1103
 None
 1.36A 4v32C-1lu4A:
0.0		 4v32C-1lu4A:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_A_EF2A151_1
(CEREBLON ISOFORM 4)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 8 ASN A1040
PHE A1073
PHE A1038
TRP A1030
 None
 1.37A 5amkA-1lu4A:
0.0		 5amkA-1lu4A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_D_HISD402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		5 / 8 GLY A1019
LEU A1022
GLN A1023
VAL A1104
LEU A1029
 None
 1.49A 6czmD-1lu4A:
undetectable
6czmF-1lu4A:
undetectable		 6czmD-1lu4A:
15.71
6czmF-1lu4A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 5 LEU A1079
LEU A1012
THR A1033
ARG A1094
 None
 1.03A 6ew0F-1lu4A:
1.8		 6ew0F-1lu4A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 1lu4 SOLUBLE SECRETED
ANTIGEN MPT53
(Mycobacterium
tuberculosis) 		4 / 6 LEU A1079
LEU A1012
THR A1033
ARG A1094
 None
 1.03A 6ew0G-1lu4A:
1.8		 6ew0G-1lu4A:
21.21