SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1luf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 MET A 712
LEU A 715
SER A 716
None
0.68A 1ee2A-1lufA:
0.0
1ee2A-1lufA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 TRP A 767
VAL A 784
TRP A 785
None
1.12A 1gmkC-1lufA:
undetectable
1gmkD-1lufA:
undetectable
1gmkC-1lufA:
4.56
1gmkD-1lufA:
4.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 LYS A 608
VAL A 638
MET A 657
ARG A 723
None
0.95A 1iepA-1lufA:
35.4
1iepA-1lufA:
37.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLF_A_NVPA999_1
(HIV-1 RT A-CHAIN
HIV-1 RT B-CHAIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 8 LEU A 666
VAL A 732
CYH A 730
GLY A 660
None
1.00A 1jlfA-1lufA:
0.0
1jlfB-1lufA:
undetectable
1jlfA-1lufA:
18.25
1jlfB-1lufA:
19.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OPJ_B_STIB4_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
VAL A 638
GLY A 660
ALA A 741
ASP A 742
None
0.74A 1opjB-1lufA:
34.1
1opjB-1lufA:
37.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 ILE A 580
VAL A 588
LYS A 608
VAL A 638
PHE A 654
ASP A 661
ASN A 729
LEU A 731
ALA A 741
None
0.87A 2eufB-1lufA:
23.8
2eufB-1lufA:
27.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EUF_B_LQQB401_1
(CELL DIVISION
PROTEIN KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 ILE A 580
VAL A 638
PHE A 654
ASP A 661
ASN A 729
LEU A 731
ALA A 741
ASP A 742
None
0.85A 2eufB-1lufA:
23.8
2eufB-1lufA:
27.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GQG_B_1N1B502_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
GLY A 660
LEU A 731
ALA A 741
None
0.60A 2gqgB-1lufA:
31.9
2gqgB-1lufA:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_A_STIA600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.71A 2hyyA-1lufA:
35.5
2hyyA-1lufA:
37.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_B_STIB600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.68A 2hyyB-1lufA:
35.9
2hyyB-1lufA:
37.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HYY_C_STIC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
VAL A 638
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.76A 2hyyC-1lufA:
30.2
2hyyC-1lufA:
37.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KOT_A_ANWA99_0
(PROTEIN S100-A13)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 7 MET A 604
VAL A 607
PHE A 589
ARG A 578
None
1.21A 2kotA-1lufA:
0.0
2kotA-1lufA:
15.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
LYS A 608
TYR A 656
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.70A 2oiqA-1lufA:
28.0
2oiqA-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OIQ_A_STIA1001_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
LYS A 608
MET A 629
TYR A 656
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.98A 2oiqA-1lufA:
28.0
2oiqA-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2PL0_A_STIA200_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE LCK)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 629
VAL A 638
TYR A 656
LEU A 731
ALA A 741
ASP A 742
None
1.19A 2pl0A-1lufA:
32.3
2pl0A-1lufA:
34.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2WGJ_A_VGHA2346_1
(HEPATOCYTE GROWTH
FACTOR RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
TYR A 656
MET A 657
GLY A 660
ALA A 741
ASP A 742
None
0.80A 2wgjA-1lufA:
34.9
2wgjA-1lufA:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2XP2_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
GLY A 660
LEU A 731
ASP A 742
None
0.68A 2xp2A-1lufA:
32.7
2xp2A-1lufA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y6O_A_1N1A1892_1
(EPHRIN TYPE-A
RECEPTOR 4)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ILE A 580
ALA A 606
LYS A 608
MET A 629
TYR A 656
GLY A 660
LEU A 731
None
1.15A 2y6oA-1lufA:
34.1
2y6oA-1lufA:
35.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_A_B49A1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ILE A 580
VAL A 588
ALA A 606
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.84A 2y7jA-1lufA:
24.3
2y7jA-1lufA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_B_B49B1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 10 ILE A 580
VAL A 588
ALA A 606
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.92A 2y7jB-1lufA:
24.6
2y7jB-1lufA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_C_B49C1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 10 ILE A 580
VAL A 588
ALA A 606
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.91A 2y7jC-1lufA:
24.2
2y7jC-1lufA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7J_D_B49D1294_1
(PHOSPHORYLASE B
KINASE GAMMA
CATALYTIC CHAIN,
TESTIS/LIVER ISOFORM)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 10 ILE A 580
VAL A 588
ALA A 606
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.94A 2y7jD-1lufA:
24.3
2y7jD-1lufA:
24.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YFX_A_VGHA9000_1
(TYROSINE-PROTEIN
KINASE RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 8 ALA A 606
MET A 657
GLY A 660
LEU A 731
None
0.30A 2yfxA-1lufA:
26.7
2yfxA-1lufA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZVA_A_1N1A513_1
(TYROSINE-PROTEIN
KINASE LYN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
MET A 629
VAL A 638
MET A 657
GLY A 660
LEU A 731
ALA A 741
None
0.74A 2zvaA-1lufA:
32.5
2zvaA-1lufA:
32.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_A_NILA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
GLY A 660
PHE A 720
HIS A 722
LEU A 731
ALA A 741
None
0.60A 3cs9A-1lufA:
35.4
3cs9A-1lufA:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_C_NILC600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
PHE A 720
HIS A 722
ALA A 741
ASP A 742
None
0.59A 3cs9C-1lufA:
27.9
3cs9C-1lufA:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CS9_D_NILD600_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
GLY A 660
PHE A 720
HIS A 722
ALA A 741
None
0.49A 3cs9D-1lufA:
34.1
3cs9D-1lufA:
37.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G0F_A_B49A9001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 11 VAL A 588
ALA A 606
TYR A 656
GLY A 660
ASP A 661
LEU A 731
None
0.57A 3g0fA-1lufA:
35.1
3g0fA-1lufA:
36.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GN8_A_DEXA247_2
(GLUCOCORTICOID
RECEPTOR 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 MET A 629
MET A 650
PHE A 743
None
0.95A 3gn8A-1lufA:
0.0
3gn8A-1lufA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GP0_A_NILA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 11)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 7 LYS A 608
LEU A 652
MET A 657
ILE A 740
None
0.94A 3gp0A-1lufA:
23.1
3gp0A-1lufA:
23.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GVU_A_STIA1001_1
(TYROSINE-PROTEIN
KINASE ABL2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
0.74A 3gvuA-1lufA:
34.3
3gvuA-1lufA:
38.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IK3_A_0LIA1_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
HIS A 722
LEU A 731
ALA A 741
ASP A 742
None
0.67A 3ik3A-1lufA:
34.5
3ik3A-1lufA:
36.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_A_STIA2_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.73A 3k5vA-1lufA:
34.2
3k5vA-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3K5V_B_STIB2_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.71A 3k5vB-1lufA:
34.1
3k5vB-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_A_B49A1_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 11 ALA A 606
VAL A 638
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.72A 3miyA-1lufA:
32.5
3miyA-1lufA:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MIY_B_B49B2_1
(TYROSINE-PROTEIN
KINASE ITK/TSK)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 9 ALA A 606
PHE A 654
MET A 657
GLY A 660
LEU A 731
None
0.68A 3miyB-1lufA:
32.5
3miyB-1lufA:
32.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 LYS A 608
VAL A 638
MET A 657
ARG A 723
None
0.73A 3ms9A-1lufA:
34.7
3ms9A-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 LYS A 608
VAL A 638
MET A 657
ARG A 723
None
0.77A 3mssA-1lufA:
35.1
3mssA-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 7 LYS A 608
VAL A 638
MET A 657
ARG A 723
None
0.95A 3mssB-1lufA:
35.0
3mssB-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 LYS A 608
VAL A 638
MET A 657
ARG A 723
None
0.81A 3mssC-1lufA:
35.0
3mssC-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
MET A 629
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
1.10A 3mssD-1lufA:
35.0
3mssD-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MSS_D_STID1_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 VAL A 588
LYS A 608
VAL A 638
MET A 657
None
0.75A 3mssD-1lufA:
35.0
3mssD-1lufA:
37.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OCT_A_1N1A663_1
(TYROSINE-PROTEIN
KINASE BTK)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 629
VAL A 638
TYR A 656
GLY A 660
LEU A 731
None
1.04A 3octA-1lufA:
31.6
3octA-1lufA:
30.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_A_STIA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
VAL A 638
TYR A 656
GLY A 660
LEU A 731
ALA A 741
None
0.52A 3oezA-1lufA:
27.8
3oezA-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OEZ_B_STIB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 629
TYR A 656
LEU A 731
ALA A 741
ASP A 742
None
1.19A 3oezB-1lufA:
27.6
3oezB-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3OXZ_A_0LIA1_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
VAL A 638
GLY A 660
HIS A 722
ALA A 741
ASP A 742
None
0.69A 3oxzA-1lufA:
33.7
3oxzA-1lufA:
36.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QLG_A_1N1A601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 629
VAL A 638
TYR A 656
GLY A 660
LEU A 731
ALA A 741
None
0.95A 3qlgA-1lufA:
27.2
3qlgA-1lufA:
32.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_1
(CYCLIN-DEPENDENT
KINASE 8)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
PHE A 654
TYR A 656
LEU A 715
HIS A 722
ALA A 741
None
0.76A 3rgfA-1lufA:
21.4
3rgfA-1lufA:
25.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 ILE A 580
ALA A 606
VAL A 638
PHE A 654
ASP A 661
LEU A 731
None
0.66A 3ti1A-1lufA:
22.9
3ti1A-1lufA:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 5 THR A 603
GLY A 595
PRO A 598
TYR A 599
None
1.19A 3u8qA-1lufA:
undetectable
3u8qA-1lufA:
22.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG2_A_IREA1_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
LYS A 608
LEU A 652
MET A 657
GLY A 660
LEU A 731
None
0.84A 3ug2A-1lufA:
24.8
3ug2A-1lufA:
31.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_1
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ILE A 580
GLY A 583
GLY A 586
VAL A 588
ALA A 606
LYS A 608
None
0.71A 3v5wA-1lufA:
7.9
3v5wA-1lufA:
19.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 8 VAL A 638
LEU A 731
ILE A 740
ASP A 742
None
0.59A 3wzeA-1lufA:
29.3
3wzeA-1lufA:
34.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZBF_A_VGHA3000_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ROS)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
MET A 657
GLY A 660
ASP A 661
LEU A 731
None
0.30A 3zbfA-1lufA:
33.4
3zbfA-1lufA:
35.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
LEU A 715
HIS A 722
LEU A 731
ALA A 741
ASP A 742
None
0.74A 3zosA-1lufA:
28.5
3zosA-1lufA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_A_0LIA1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 9 MET A 629
ILE A 637
TYR A 656
MET A 657
ILE A 740
None
0.69A 3zosA-1lufA:
28.5
3zosA-1lufA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
LEU A 715
HIS A 722
LEU A 731
ALA A 741
ASP A 742
None
0.73A 3zosB-1lufA:
35.7
3zosB-1lufA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 9 MET A 629
ILE A 637
TYR A 656
MET A 657
ILE A 740
None
0.71A 3zosB-1lufA:
35.7
3zosB-1lufA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
GLY A 660
LEU A 731
ALA A 741
None
0.64A 4anqA-1lufA:
32.6
4anqA-1lufA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANQ_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
LEU A 731
ALA A 741
ASP A 742
None
0.68A 4anqA-1lufA:
32.6
4anqA-1lufA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
GLY A 660
LEU A 731
ALA A 741
None
0.65A 4ansA-1lufA:
32.6
4ansA-1lufA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ANS_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
LEU A 731
ALA A 741
ASP A 742
None
0.69A 4ansA-1lufA:
32.6
4ansA-1lufA:
36.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_A_STIA1000_1
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
MET A 629
TYR A 656
LEU A 731
ALA A 741
ASP A 742
None
0.89A 4bkjA-1lufA:
28.9
4bkjA-1lufA:
39.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4BKJ_B_STIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 5 LYS A 608
TYR A 656
MET A 657
ARG A 723
None
0.89A 4bkjB-1lufA:
36.1
4bkjB-1lufA:
39.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_A_0LIA1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 5 VAL A 588
ILE A 637
TYR A 656
MET A 657
ILE A 740
None
0.45A 4c8bA-1lufA:
27.8
4c8bA-1lufA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_1
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
ILE A 637
HIS A 722
LEU A 731
ALA A 741
ASP A 742
None
0.68A 4c8bB-1lufA:
27.3
4c8bB-1lufA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 TYR A 656
MET A 657
ILE A 637
None
0.55A 4c8bB-1lufA:
27.3
4c8bB-1lufA:
27.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C8B_B_0LIB1000_2
(RECEPTOR-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 2)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 TYR A 656
MET A 657
ILE A 740
None
0.19A 4c8bB-1lufA:
27.3
4c8bB-1lufA:
27.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CKI_A_ADNA2022_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 11 GLY A 581
VAL A 588
ALA A 606
TYR A 656
GLY A 660
LEU A 731
None
0.74A 4ckiA-1lufA:
26.8
4ckiA-1lufA:
37.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CSV_A_STIA1265_1
(SRC-ABL TYROSINE
KINASE ANCESTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
MET A 629
VAL A 638
TYR A 656
LEU A 731
ALA A 741
ASP A 742
None
1.01A 4csvA-1lufA:
33.8
4csvA-1lufA:
38.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_A_8PRA601_1
(RHODOPSIN KINASE)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 7 ALA A 606
MET A 657
ASP A 661
LEU A 731
None
0.81A 4l9iA-1lufA:
8.2
4l9iA-1lufA:
22.24
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXX_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
VAL A 638
TYR A 656
MET A 657
GLY A 660
LEU A 731
None
0.53A 4mxxB-1lufA:
32.1
4mxxB-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXY_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
TYR A 656
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.86A 4mxyB-1lufA:
25.7
4mxyB-1lufA:
33.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4MXZ_B_DB8B601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
TYR A 656
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.86A 4mxzB-1lufA:
25.7
4mxzB-1lufA:
33.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 SER A 782
ALA A 786
VAL A 789
None
0.62A 4o2bC-1lufA:
undetectable
4o2bC-1lufA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_E_ADNE401_1
(CYCLIN-DEPENDENT
KINASE 9)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 7 ALA A 606
ASP A 661
ASN A 729
LEU A 731
ASP A 742
None
0.89A 4ogrE-1lufA:
22.6
4ogrE-1lufA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 ILE A 580
GLY A 744
ALA A 606
ASP A 661
ASN A 729
LEU A 731
None
0.88A 4ogrI-1lufA:
22.8
4ogrI-1lufA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 ILE A 580
GLY A 744
ASP A 661
ASN A 729
LEU A 731
ASP A 742
None
0.99A 4ogrI-1lufA:
22.8
4ogrI-1lufA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGR_I_ADNI401_1
(CYCLIN-DEPENDENT
KINASE 9)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 ILE A 580
VAL A 588
ALA A 606
ASP A 661
ASN A 729
LEU A 731
None
0.91A 4ogrI-1lufA:
22.8
4ogrI-1lufA:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 10 LEU A 855
CYH A 698
LEU A 702
ALA A 705
LEU A 791
None
1.00A 4p65A-1lufA:
undetectable
4p65B-1lufA:
undetectable
4p65F-1lufA:
undetectable
4p65H-1lufA:
undetectable
4p65A-1lufA:
4.47
4p65B-1lufA:
6.34
4p65F-1lufA:
6.34
4p65H-1lufA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 11 LEU A 855
CYH A 698
LEU A 702
ALA A 705
LEU A 791
None
0.99A 4p65C-1lufA:
undetectable
4p65D-1lufA:
undetectable
4p65J-1lufA:
undetectable
4p65L-1lufA:
undetectable
4p65C-1lufA:
4.47
4p65D-1lufA:
6.34
4p65J-1lufA:
6.34
4p65L-1lufA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 11 LEU A 791
LEU A 855
CYH A 698
LEU A 702
ALA A 705
None
1.04A 4p65B-1lufA:
undetectable
4p65D-1lufA:
undetectable
4p65G-1lufA:
undetectable
4p65H-1lufA:
undetectable
4p65B-1lufA:
6.34
4p65D-1lufA:
6.34
4p65G-1lufA:
4.47
4p65H-1lufA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 LEU A 791
LEU A 855
CYH A 698
LEU A 702
ALA A 705
None
0.96A 4p65B-1lufA:
undetectable
4p65D-1lufA:
undetectable
4p65I-1lufA:
undetectable
4p65J-1lufA:
undetectable
4p65B-1lufA:
6.34
4p65D-1lufA:
6.34
4p65I-1lufA:
4.47
4p65J-1lufA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_K_IPHK101_0
(INSULIN)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 LEU A 791
LEU A 855
CYH A 698
LEU A 702
ALA A 705
None
1.04A 4p65F-1lufA:
undetectable
4p65H-1lufA:
undetectable
4p65K-1lufA:
undetectable
4p65L-1lufA:
undetectable
4p65F-1lufA:
6.34
4p65H-1lufA:
6.34
4p65K-1lufA:
4.47
4p65L-1lufA:
6.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QMN_A_DB8A401_1
(SERINE/THREONINE-PRO
TEIN KINASE 24)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
LYS A 608
TYR A 656
LEU A 731
ALA A 741
ASP A 742
None
0.74A 4qmnA-1lufA:
26.5
4qmnA-1lufA:
24.31
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QRC_A_0LIA802_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 8 VAL A 588
LYS A 608
HIS A 722
LEU A 731
None
0.72A 4qrcA-1lufA:
34.2
4qrcA-1lufA:
40.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_A_AXIA601_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
ASP A 742
None
0.64A 4twpA-1lufA:
32.3
4twpA-1lufA:
35.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWP_B_AXIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
ASP A 742
None
0.65A 4twpB-1lufA:
32.6
4twpB-1lufA:
35.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
HIS A 722
LEU A 731
ALA A 741
ASP A 742
None
0.66A 4tyjA-1lufA:
34.4
4tyjA-1lufA:
41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TYJ_A_0LIA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 6 VAL A 588
LYS A 608
ILE A 637
ARG A 723
ILE A 740
None
0.99A 4tyjA-1lufA:
34.4
4tyjA-1lufA:
41.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_1
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 10 VAL A 588
ILE A 637
VAL A 638
TYR A 656
ARG A 723
ILE A 740
None
0.82A 4u0iA-1lufA:
36.3
4u0iA-1lufA:
36.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U0I_A_0LIA1001_2
(MAST/STEM CELL
GROWTH FACTOR
RECEPTOR
KIT,MAST/STEM CELL
GROWTH FACTOR
RECEPTOR KIT)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
LYS A 608
GLY A 660
HIS A 722
LEU A 731
ASP A 742
None
0.60A 4u0iA-1lufA:
36.3
4u0iA-1lufA:
36.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_A_RXTA601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
10 / 11 GLY A 583
VAL A 588
ALA A 606
TYR A 656
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
ASP A 742
None
0.92A 4u5jA-1lufA:
32.9
4u5jA-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4U5J_B_RXTB601_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 9 VAL A 588
ALA A 606
TYR A 656
MET A 657
GLY A 660
LEU A 731
ASP A 742
None
0.62A 4u5jB-1lufA:
27.1
4u5jB-1lufA:
32.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UXQ_A_0LIA1752_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 4)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
LEU A 715
HIS A 722
LEU A 731
ALA A 741
None
0.53A 4uxqA-1lufA:
34.8
4uxqA-1lufA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
LEU A 715
HIS A 722
ALA A 741
ASP A 742
None
0.69A 4v01A-1lufA:
34.0
4v01A-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_A_0LIA1776_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
LYS A 608
TYR A 656
ARG A 723
LEU A 731
ILE A 740
None
1.03A 4v01A-1lufA:
34.0
4v01A-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
LEU A 715
HIS A 722
ALA A 741
ASP A 742
None
0.62A 4v01B-1lufA:
34.3
4v01B-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V01_B_0LIB1770_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
LYS A 608
TYR A 656
ARG A 723
LEU A 731
ILE A 740
None
0.77A 4v01B-1lufA:
34.3
4v01B-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 588
ALA A 606
LEU A 715
HIS A 722
ALA A 741
ASP A 742
None
0.80A 4v04A-1lufA:
33.6
4v04A-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 8 LYS A 608
TYR A 656
ARG A 723
LEU A 731
ILE A 740
None
1.31A 4v04A-1lufA:
33.6
4v04A-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_1
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 10 VAL A 588
LYS A 608
TYR A 656
ARG A 723
LEU A 731
ILE A 740
None
1.17A 4v04B-1lufA:
34.4
4v04B-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 ALA A 606
LEU A 715
HIS A 722
ALA A 741
ASP A 742
None
0.64A 4v04B-1lufA:
34.4
4v04B-1lufA:
38.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_A_AXIA9000_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 11 ALA A 606
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
None
0.48A 4wa9A-1lufA:
28.4
4wa9A-1lufA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4WA9_B_AXIB9000_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
LYS A 608
MET A 657
GLY A 660
ASN A 729
LEU A 731
ALA A 741
None
0.58A 4wa9B-1lufA:
32.4
4wa9B-1lufA:
36.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_A_1N1A601_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 ALA A 606
LYS A 608
MET A 629
VAL A 638
TYR A 656
MET A 657
GLY A 660
LEU A 731
ALA A 741
None
0.99A 4xliA-1lufA:
32.9
4xliA-1lufA:
37.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4XLI_B_1N1B600_1
(NON-SPECIFIC
PROTEIN-TYROSINE
KINASE)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
VAL A 638
TYR A 656
GLY A 660
LEU A 731
ALA A 741
None
0.58A 4xliB-1lufA:
32.7
4xliB-1lufA:
37.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4ZAU_A_YY3A1101_1
(EPIDERMAL GROWTH
FACTOR RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 8 GLY A 581
VAL A 588
ALA A 606
MET A 657
GLY A 660
None
0.52A 4zauA-1lufA:
31.0
4zauA-1lufA:
31.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 LEU A 628
ALA A 630
LEU A 652
LEU A 640
LEU A 564
None
1.19A 4zn7A-1lufA:
undetectable
4zn7A-1lufA:
21.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAA_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 9 VAL A 588
ALA A 606
MET A 657
GLY A 660
LEU A 731
ASP A 742
None
0.67A 5aaaA-1lufA:
33.1
5aaaA-1lufA:
35.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AAB_A_VGHA9000_1
(ALK TYROSINE KINASE
RECEPTOR)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 10 VAL A 588
ALA A 606
LYS A 608
MET A 657
GLY A 660
LEU A 731
ASP A 742
None
0.86A 5aabA-1lufA:
32.7
5aabA-1lufA:
35.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_B_DB8B800_1
(SERINE/THREONINE-PRO
TEIN KINASE 10)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 10 ALA A 606
GLY A 660
LEU A 731
ALA A 741
ASP A 742
None
0.61A 5ajqB-1lufA:
23.5
5ajqB-1lufA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 8 VAL A 588
ILE A 637
ILE A 740
ASP A 742
None
0.47A 5hi2A-1lufA:
20.1
5hi2A-1lufA:
29.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 6 GLY A 798
ASP A 724
ILE A 765
ARG A 766
None
1.04A 5iwuA-1lufA:
6.8
5iwuA-1lufA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 ILE A 580
GLY A 581
VAL A 588
ALA A 606
VAL A 638
PHE A 654
ASP A 661
LEU A 731
None
0.71A 5l2iA-1lufA:
7.0
5l2iA-1lufA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2I_A_LQQA900_1
(CYCLIN-DEPENDENT
KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 ILE A 580
VAL A 588
ALA A 606
VAL A 638
PHE A 654
ASP A 661
LEU A 731
ALA A 741
None
0.66A 5l2iA-1lufA:
7.0
5l2iA-1lufA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
9 / 12 ILE A 580
GLY A 581
VAL A 588
ALA A 606
VAL A 638
PHE A 654
ASP A 661
LEU A 731
ALA A 741
None
0.87A 5l2tA-1lufA:
7.1
5l2tA-1lufA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L2T_A_6ZZA900_1
(CYCLIN-DEPENDENT
KINASE 6)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 VAL A 638
PHE A 654
ASP A 661
LEU A 731
ALA A 741
ASP A 742
None
0.83A 5l2tA-1lufA:
7.1
5l2tA-1lufA:
26.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
6 / 12 ALA A 606
VAL A 638
PHE A 720
HIS A 722
LEU A 731
ALA A 741
None
0.71A 5mo4A-1lufA:
12.0
5mo4A-1lufA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MO4_A_NILA601_2
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 VAL A 638
PHE A 720
HIS A 722
ALA A 741
ASP A 742
None
0.65A 5mo4A-1lufA:
12.0
5mo4A-1lufA:
29.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC3_A_DB8A601_2
(WEE1-LIKE PROTEIN
KINASE)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 4 VAL A 588
LYS A 608
VAL A 638
ASN A 729
None
0.89A 5vc3A-1lufA:
23.4
5vc3A-1lufA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 12 GLY A 581
VAL A 588
ALA A 606
PHE A 654
ALA A 741
None
0.63A 5xv7A-1lufA:
21.1
5xv7A-1lufA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZV2_A_LEVA801_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
3 / 3 LYS A 608
LEU A 731
ASP A 742
None
0.91A 5zv2A-1lufA:
33.0
5zv2A-1lufA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSD_A_1N1A901_0
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
8 / 12 VAL A 588
ALA A 606
LYS A 608
TYR A 656
MET A 657
GLY A 660
LEU A 731
ASP A 742
None
1.16A 6bsdA-1lufA:
28.2
6bsdA-1lufA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_A_HISA402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
5 / 10 GLY A 595
LEU A 596
VAL A 607
ALA A 591
LEU A 653
None
1.16A 6czmA-1lufA:
undetectable
6czmC-1lufA:
undetectable
6czmA-1lufA:
21.43
6czmC-1lufA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
MET A 629
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
1.16A 6hd4A-1lufA:
34.0
6hd4A-1lufA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_A_STIA604_0
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
0.86A 6hd4A-1lufA:
34.0
6hd4A-1lufA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 ALA A 606
LYS A 608
MET A 629
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
1.18A 6hd4B-1lufA:
34.0
6hd4B-1lufA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD4_B_STIB602_0
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
0.89A 6hd4B-1lufA:
34.0
6hd4B-1lufA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_A_STIA603_0
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
7 / 12 VAL A 588
ALA A 606
LYS A 608
VAL A 638
LEU A 731
ALA A 741
ASP A 742
None
0.86A 6hd6A-1lufA:
34.1
6hd6A-1lufA:
31.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6HD6_B_STIB601_1
(TYROSINE-PROTEIN
KINASE ABL1)
1luf MUSCLE-SPECIFIC
TYROSINE KINASE
RECEPTOR MUSK

(Rattus
norvegicus)
4 / 7 MET A 657
GLY A 660
ARG A 723
ALA A 741
None
0.44A 6hd6B-1lufA:
33.9
6hd6B-1lufA:
31.03