SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1luj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 8 VAL A 199
VAL A 195
SER A 191
LEU A 221
 None
 0.84A 1igxA-1lujA:
undetectable		 1igxA-1lujA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 THR A 297
LEU A 324
ILE A 315
GLY A 320
LEU A 286
 None
 0.97A 2ouzA-1lujA:
0.3		 2ouzA-1lujA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 1luj BETA-CATENIN-INTERAC
TING PROTEIN 1
CATENIN BETA-1
(Homo
sapiens;
Mus
musculus) 		5 / 10 ALA A 656
LEU B  41
LEU B  33
LEU B  23
ARG B  21
 None
 1.18A 2xn6A-1lujA:
0.0
2xn6B-1lujA:
undetectable		 2xn6A-1lujA:
20.62
2xn6B-1lujA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 6 THR A 574
GLY A 572
ILE A 569
LEU A 536
 None
 1.13A 4ac9C-1lujA:
undetectable		 4ac9C-1lujA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 6 THR A 574
GLY A 572
ILE A 569
LEU A 536
 None
 1.10A 4acaC-1lujA:
undetectable		 4acaC-1lujA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9I_B_8PRB601_1
(RHODOPSIN KINASE)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 8 GLY A 320
VAL A 325
ALA A 365
MET A 363
LEU A 388
 None
 1.18A 4l9iB-1lujA:
undetectable		 4l9iB-1lujA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1luj CATENIN BETA-1
(Homo
sapiens) 		6 / 12 LEU A 218
ILE A 188
ALA A 197
THR A 157
ALA A 171
VAL A 175
 None
 1.37A 4nkxB-1lujA:
undetectable		 4nkxB-1lujA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 277
ALA A 276
ASN A 308
SER A 311
ILE A 314
 None
 1.13A 4pb1A-1lujA:
undetectable		 4pb1A-1lujA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 278
ALA A 276
ASN A 308
SER A 311
ILE A 314
 None
 1.20A 4pb1A-1lujA:
undetectable		 4pb1A-1lujA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 277
ALA A 276
ASN A 308
SER A 311
ILE A 314
 None
 1.18A 4pd5A-1lujA:
0.8		 4pd5A-1lujA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 277
ALA A 276
ASN A 308
SER A 311
ILE A 314
 None
 1.15A 4pd9A-1lujA:
0.0		 4pd9A-1lujA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 278
ALA A 276
ASN A 308
SER A 311
ILE A 314
 None
 1.18A 4pd9A-1lujA:
0.0		 4pd9A-1lujA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 10 ASN A 431
ASN A 434
VAL A 438
LEU A 402
LEU A 424
 None
 1.16A 4po0A-1lujA:
2.2		 4po0A-1lujA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)		 1luj CATENIN BETA-1
BETA-CATENIN-INTERAC
TING PROTEIN 1
(Homo
sapiens;
Mus
musculus) 		5 / 12 GLY A 572
ALA B  64
ILE A 569
VAL A 511
ILE A 507
 None
 0.99A 4uw0A-1lujA:
undetectable		 4uw0A-1lujA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 11 LEU A 401
LEU A 370
LEU A 382
ARG A 386
LEU A 385
 None
 1.15A 4wg0I-1lujA:
undetectable
4wg0J-1lujA:
undetectable
4wg0K-1lujA:
undetectable		 4wg0I-1lujA:
2.51
4wg0J-1lujA:
2.51
4wg0K-1lujA:
2.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUM_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 8 VAL A 617
ILE A 631
LEU A 621
ILE A 596
SER A 605
 None
 1.14A 5numA-1lujA:
undetectable		 5numA-1lujA:
10.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 7 ILE A 256
LEU A 259
ILE A 315
ALA A 272
 None
 0.82A 6b5vA-1lujA:
0.0
6b5vC-1lujA:
0.0		 6b5vA-1lujA:
9.98
6b5vC-1lujA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 7 ALA A 272
ILE A 256
LEU A 259
ILE A 315
 None
 0.81A 6b5vA-1lujA:
undetectable
6b5vB-1lujA:
undetectable		 6b5vA-1lujA:
9.98
6b5vB-1lujA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_B_ECLB1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 7 ALA A 305
ILE A 327
LEU A 324
ILE A 256
 None
 0.72A 6b5vA-1lujA:
undetectable
6b5vB-1lujA:
undetectable		 6b5vA-1lujA:
9.98
6b5vB-1lujA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 7 ILE A 256
LEU A 259
ILE A 315
ALA A 272
 None
 0.83A 6b5vC-1lujA:
0.0
6b5vD-1lujA:
0.0		 6b5vC-1lujA:
9.98
6b5vD-1lujA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 1luj CATENIN BETA-1
(Homo
sapiens) 		4 / 7 ALA A 272
ILE A 256
LEU A 259
ILE A 315
 None
 0.81A 6b5vB-1lujA:
0.0
6b5vD-1lujA:
0.0		 6b5vB-1lujA:
9.98
6b5vD-1lujA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 GLY A 319
ALA A 323
ASN A 353
SER A 352
VAL A 346
 None
 0.94A 6bqgA-1lujA:
undetectable		 6bqgA-1lujA:
9.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1luj CATENIN BETA-1
(Homo
sapiens) 		5 / 12 LEU A 498
ILE A 569
VAL A 564
LEU A 577
ALA A 576
 None
 1.21A 6djzA-1lujA:
undetectable		 6djzA-1lujA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1luj CATENIN BETA-1
(Homo
sapiens) 		3 / 3 ARG A 515
HIS A 578
ARG A 582
 None
 1.01A 6dwdD-1lujA:
0.0		 6dwdD-1lujA:
21.38