SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lv7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 1lv7 FTSH
(Escherichia
coli) 		5 / 12 GLY A 260
LEU A 278
LEU A 282
ALA A 298
PHE A 316
 None
 0.91A 1gseA-1lv7A:
undetectable		 1gseA-1lv7A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 1lv7 FTSH
(Escherichia
coli) 		5 / 12 GLY A 260
LEU A 278
LEU A 282
ALA A 298
PHE A 316
 None
 0.93A 1gseB-1lv7A:
undetectable		 1gseB-1lv7A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1lv7 FTSH
(Escherichia
coli) 		6 / 12 ILE A 253
ALA A 298
LEU A 306
ALA A 299
VAL A 236
LEU A 282
 None
 1.40A 1k74A-1lv7A:
undetectable		 1k74A-1lv7A:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA156_1
(CALMODULIN)		 1lv7 FTSH
(Escherichia
coli) 		5 / 8 ILE A 256
LEU A 192
VAL A 296
ILE A 253
MET A 285
 None
 1.37A 1linA-1lv7A:
undetectable		 1linA-1lv7A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 ASP A 286
PHE A 240
ASN A 279
 None
 0.73A 1sg9B-1lv7A:
3.1		 1sg9B-1lv7A:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_A_ACTA1397_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 PRO A 177
GLY A 293
TYR A 173
 None
 0.59A 2vouA-1lv7A:
undetectable		 2vouA-1lv7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_B_ACTB1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 PRO A 177
GLY A 293
TYR A 173
 None
 0.67A 2vouB-1lv7A:
0.0		 2vouB-1lv7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VOU_C_ACTC1391_0
(2,6-DIHYDROXYPYRIDIN
E HYDROXYLASE)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 PRO A 177
GLY A 293
TYR A 173
 None
 0.68A 2vouC-1lv7A:
0.0		 2vouC-1lv7A:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 THR A 277
SER A 220
LYS A 144
 None
 0.87A 3aocC-1lv7A:
undetectable		 3aocC-1lv7A:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1lv7 FTSH
(Escherichia
coli) 		5 / 12 PHE A 216
ILE A 250
MET A 281
VAL A 259
ILE A 256
 None
 1.39A 3em0B-1lv7A:
undetectable		 3em0B-1lv7A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1lv7 FTSH
(Escherichia
coli) 		5 / 11 ILE A 256
GLN A 319
PHE A 316
LEU A 306
ILE A 219
 None
 1.00A 3fc6A-1lv7A:
undetectable		 3fc6A-1lv7A:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_A_NCTA501_1
(CYTOCHROME P450 2A6)		 1lv7 FTSH
(Escherichia
coli) 		4 / 7 PHE A 288
GLY A 190
ILE A 251
PHE A 240
 None
 0.85A 4ejjA-1lv7A:
undetectable		 4ejjA-1lv7A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L94_A_TESA502_1
(CYTOCHROME P450)		 1lv7 FTSH
(Escherichia
coli) 		5 / 8 VAL A 167
ILE A 208
ALA A 205
VAL A 322
VAL A 320
 None
 1.28A 5l94A-1lv7A:
undetectable		 5l94A-1lv7A:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1lv7 FTSH
(Escherichia
coli) 		3 / 3 ILE A 297
VAL A 191
PRO A 188
 None
 0.63A 5uunA-1lv7A:
undetectable		 5uunA-1lv7A:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1lv7 FTSH
(Escherichia
coli) 		6 / 12 ILE A 253
ALA A 298
LEU A 306
ALA A 299
VAL A 236
LEU A 282
 None
 1.40A 5z12B-1lv7A:
undetectable		 5z12B-1lv7A:
14.96