SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lvl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 ALA A 316
ALA A 141
LEU A  33
VAL A 111
ILE A  10
 FAD  A 459 ( 3.7A)
FAD  A 459 (-4.5A)
None
None
None
 1.31A 1claA-1lvlA:
0.0		 1claA-1lvlA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_0
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A 261
ALA A 164
PRO A  50
GLY A 183
ILE A 182
 None
None
None
None
NAD  A 460 (-3.6A)
 1.22A 1kglA-1lvlA:
0.2		 1kglA-1lvlA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEH_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 SER A 160
SER A 161
ILE A  46
GLY A  47
GLY A 183
 None
FAD  A 459 ( 4.0A)
None
FAD  A 459 (-3.3A)
None
 1.27A 1mehA-1lvlA:
undetectable		 1mehA-1lvlA:
24.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 GLY A 304
GLY A 320
GLN A 319
GLY A  14
GLY A  13
 FAD  A 459 ( 3.8A)
None
None
FAD  A 459 ( 4.0A)
FAD  A 459 ( 4.9A)
 1.00A 1mxgA-1lvlA:
1.2		 1mxgA-1lvlA:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 THR A 270
ILE A 303
GLY A 304
GLY A 308
ILE A 287
 None
None
FAD  A 459 ( 3.8A)
None
None
 1.03A 1nv8B-1lvlA:
3.7		 1nv8B-1lvlA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 GLY A  12
VAL A  34
LEU A   9
LEU A 138
ALA A 118
 FAD  A 459 (-3.2A)
FAD  A 459 ( 4.9A)
None
None
FAD  A 459 (-3.6A)
 1.20A 1pbcA-1lvlA:
10.3		 1pbcA-1lvlA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 THR A 270
ILE A 303
GLY A 304
GLY A 308
ILE A 287
 None
None
FAD  A 459 ( 3.8A)
None
None
 1.00A 1sg9B-1lvlA:
3.6		 1sg9B-1lvlA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_0
(HYPOTHETICAL PROTEIN
PH0226)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 ALA A 324
GLY A 320
ILE A 326
ALA A 328
ILE A  22
 None
 1.11A 1ve3A-1lvlA:
4.3		 1ve3A-1lvlA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_0
(HYPOTHETICAL PROTEIN
PH0226)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 ALA A 324
GLY A 320
ILE A 326
ALA A 328
ILE A  22
 None
 1.02A 1ve3B-1lvlA:
4.1		 1ve3B-1lvlA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 THR A 270
ILE A 303
GLY A 304
GLY A 308
ILE A 287
 None
None
FAD  A 459 ( 3.8A)
None
None
 0.98A 1vq1B-1lvlA:
3.6		 1vq1B-1lvlA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A 156
GLY A 155
LEU A 152
PRO A 153
ASN A 240
 None
 1.18A 1xdsA-1lvlA:
3.1		 1xdsA-1lvlA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A 156
GLY A 155
LEU A 152
PRO A 153
ASN A 240
 None
 1.12A 1xdsB-1lvlA:
2.6		 1xdsB-1lvlA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_D_BEZD2385_0
(CES1 PROTEIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 5 LEU A 186
LEU A 174
LEU A 170
LEU A 261
 None
 1.01A 1yajD-1lvlA:
undetectable		 1yajD-1lvlA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A 312
GLY A 308
ASP A 305
ALA A 307
ALA A 302
 FAD  A 459 (-3.6A)
None
FAD  A 459 (-3.3A)
None
None
 1.22A 2br4B-1lvlA:
2.6		 2br4B-1lvlA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_A_SAMA201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A  13
ALA A 141
GLY A 143
LEU A 139
LEU A 106
 FAD  A 459 ( 4.9A)
FAD  A 459 (-4.5A)
FAD  A 459 (-3.3A)
None
None
 1.04A 2nyuA-1lvlA:
2.5		 2nyuA-1lvlA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYU_B_SAMB201_0
(PUTATIVE RIBOSOMAL
RNA
METHYLTRANSFERASE 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A  13
ALA A 141
GLY A 143
LEU A 139
LEU A 106
 FAD  A 459 ( 4.9A)
FAD  A 459 (-4.5A)
FAD  A 459 (-3.3A)
None
None
 1.02A 2nyuB-1lvlA:
2.9		 2nyuB-1lvlA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 ILE A 182
ALA A 189
GLY A 187
GLY A 183
VAL A 197
 NAD  A 460 (-3.6A)
None
None
None
None
 1.16A 2okcB-1lvlA:
undetectable		 2okcB-1lvlA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 LEU A 106
LEU A   8
GLY A 320
MET A 317
 None
 0.93A 2po5B-1lvlA:
undetectable		 2po5B-1lvlA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 6 ARG A 266
ILE A  49
LEU A  98
TYR A  18
 FAD  A 459 ( 3.9A)
None
None
None
 1.04A 2ya7A-1lvlA:
undetectable		 2ya7A-1lvlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 6 ARG A 266
ILE A  49
LEU A  98
TYR A  18
 FAD  A 459 ( 3.9A)
None
None
None
 1.04A 2ya7B-1lvlA:
undetectable		 2ya7B-1lvlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 6 ARG A 266
ILE A  49
LEU A  98
TYR A  18
 FAD  A 459 ( 3.9A)
None
None
None
 1.02A 2ya7D-1lvlA:
0.0		 2ya7D-1lvlA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 MET A 317
ALA A 316
HIS A 314
GLY A  16
 None
FAD  A 459 ( 3.7A)
FAD  A 459 (-4.0A)
FAD  A 459 (-3.8A)
 0.91A 2zm9A-1lvlA:
0.0		 2zm9A-1lvlA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADX_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A  36
ALA A 141
ILE A  10
LEU A   9
VAL A 126
 FAD  A 459 (-3.6A)
FAD  A 459 (-4.5A)
None
None
None
 1.00A 3adxB-1lvlA:
undetectable		 3adxB-1lvlA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 5 VAL A 260
VAL A 175
GLN A 196
ARG A 191
 None
 1.27A 3bjwH-1lvlA:
0.0		 3bjwH-1lvlA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 LYS A 192
LEU A 225
ILE A 188
SER A 198
GLY A 187
 None
 1.26A 3ijxB-1lvlA:
undetectable
3ijxD-1lvlA:
undetectable		 3ijxB-1lvlA:
20.71
3ijxD-1lvlA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB262_1
(GLUTAMATE RECEPTOR 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 ILE A 188
SER A 198
GLY A 187
LYS A 192
LEU A 225
 None
 1.27A 3ik6B-1lvlA:
0.0
3ik6E-1lvlA:
0.0		 3ik6B-1lvlA:
20.71
3ik6E-1lvlA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 LYS A 192
LEU A 225
ILE A 188
SER A 198
GLY A 187
 None
 1.24A 3ik6B-1lvlA:
0.0
3ik6E-1lvlA:
0.0		 3ik6B-1lvlA:
20.71
3ik6E-1lvlA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 10 LYS A 192
LEU A 225
ILE A 188
SER A 198
GLY A 187
 None
 1.28A 3iluB-1lvlA:
0.0
3iluE-1lvlA:
0.0		 3iluB-1lvlA:
20.71
3iluE-1lvlA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 11 ILE A 188
SER A 198
GLY A 187
LYS A 192
LEU A 225
 None
 1.24A 3iluB-1lvlA:
0.0
3iluE-1lvlA:
0.0		 3iluB-1lvlA:
20.71
3iluE-1lvlA:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N3I_A_ROCA201_2
(PROTEASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 6 ILE A  49
ASP A 346
ILE A 188
VAL A 342
 None
 0.83A 3n3iA-1lvlA:
undetectable		 3n3iA-1lvlA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 VAL A 126
THR A   6
THR A   7
ILE A  29
VAL A  34
 None
None
None
None
FAD  A 459 ( 4.9A)
 1.19A 3sp9B-1lvlA:
undetectable		 3sp9B-1lvlA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLN A 252
GLY A 251
ASP A 247
GLU A 236
ALA A 245
 None
 1.27A 3t7sA-1lvlA:
3.0		 3t7sA-1lvlA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 7 ARG A 315
ALA A 316
ILE A 303
GLY A 143
 None
FAD  A 459 ( 3.7A)
None
FAD  A 459 (-3.3A)
 0.99A 3v4tH-1lvlA:
undetectable		 3v4tH-1lvlA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_A_CCSA109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 TYR A  18
VAL A  95
ILE A  49
ALA A 313
 None
None
None
FAD  A 459 (-3.5A)
 1.01A 4eyzA-1lvlA:
undetectable		 4eyzA-1lvlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYZ_B_CCSB109_0
(CELLULOSOME-RELATED
PROTEIN MODULE FROM
RUMINOCOCCUS
FLAVEFACIENS THAT
RESEMBLES
PAPAIN-LIKE CYSTEINE
PEPTIDASES)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 TYR A  18
VAL A  95
ILE A  49
ALA A 313
 None
None
None
FAD  A 459 (-3.5A)
 1.00A 4eyzB-1lvlA:
undetectable		 4eyzB-1lvlA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 GLY A  12
GLY A  13
ALA A  21
LEU A 106
GLY A 304
 FAD  A 459 (-3.2A)
FAD  A 459 ( 4.9A)
None
None
FAD  A 459 ( 3.8A)
 0.92A 4n09C-1lvlA:
3.8		 4n09C-1lvlA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_2
(TUBULIN BETA-2B
CHAIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A   8
LEU A  33
ALA A  21
ALA A 141
ILE A  11
 None
None
None
FAD  A 459 (-4.5A)
FAD  A 459 (-4.5A)
 1.10A 4o2bB-1lvlA:
undetectable		 4o2bB-1lvlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		3 / 3 VAL A 323
PHE A 334
ARG A 315
 None
 0.94A 4xr4B-1lvlA:
4.0		 4xr4B-1lvlA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 7 ALA A 141
GLY A 143
ARG A 315
GLY A 308
 FAD  A 459 (-4.5A)
FAD  A 459 (-3.3A)
None
None
 0.88A 5e26A-1lvlA:
0.0
5e26B-1lvlA:
0.0		 5e26A-1lvlA:
22.12
5e26B-1lvlA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 8 ALA A 141
GLY A 143
ARG A 315
GLY A 308
 FAD  A 459 (-4.5A)
FAD  A 459 (-3.3A)
None
None
 0.85A 5e26C-1lvlA:
undetectable
5e26D-1lvlA:
undetectable		 5e26C-1lvlA:
22.12
5e26D-1lvlA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A   8
LEU A  33
ALA A  21
ALA A 141
ILE A  11
 None
None
None
FAD  A 459 (-4.5A)
FAD  A 459 (-4.5A)
 1.06A 5itzB-1lvlA:
undetectable		 5itzB-1lvlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIO_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A   8
LEU A  33
ALA A  21
ALA A 141
ILE A  11
 None
None
None
FAD  A 459 (-4.5A)
FAD  A 459 (-4.5A)
 1.07A 5mioB-1lvlA:
undetectable		 5mioB-1lvlA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 8 LEU A 222
LEU A 214
VAL A 218
ILE A 188
GLY A 187
 None
 0.95A 5vkqB-1lvlA:
undetectable
5vkqC-1lvlA:
undetectable		 5vkqB-1lvlA:
13.86
5vkqC-1lvlA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 9 LEU A 222
LEU A 214
VAL A 218
ILE A 188
GLY A 187
 None
 0.99A 5vkqC-1lvlA:
0.0
5vkqD-1lvlA:
0.0		 5vkqC-1lvlA:
13.86
5vkqD-1lvlA:
13.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		5 / 12 LEU A 138
PHE A 273
VAL A 126
THR A  42
GLY A  41
 None
FAD  A 459 ( 4.1A)
None
FAD  A 459 (-3.7A)
FAD  A 459 (-3.3A)
 1.17A 5xipA-1lvlA:
3.5		 5xipA-1lvlA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 1lvl DIHYDROLIPOAMIDE
DEHYDROGENASE
(Pseudomonas
putida) 		4 / 4 HIS A 230
VAL A 175
LEU A 255
ALA A 228
 None
 1.35A 6d8pB-1lvlA:
undetectable		 6d8pB-1lvlA:
20.53