SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lvm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 7 THR A 180
PHE A 139
SER A 153
LEU A 204
 None
 0.99A 1qcaA-1lvmA:
0.0		 1qcaA-1lvmA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		3 / 3 LYS A 141
ILE A 109
THR A 146
 None
 0.84A 1rx3A-1lvmA:
undetectable		 1rx3A-1lvmA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 7 PRO A 154
ILE A  14
LEU A  98
ILE A  35
 None
 0.84A 2q83A-1lvmA:
undetectable		 2q83A-1lvmA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA509_0
(CHORISMATE SYNTHASE)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		3 / 3 ARG A  86
GLN A  96
PRO A  39
 None
 0.94A 2qhfA-1lvmA:
0.0		 2qhfA-1lvmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		3 / 3 SER A 153
THR A  43
PHE A  91
 None
 0.77A 2x91A-1lvmA:
0.0		 2x91A-1lvmA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		5 / 10 ILE A 163
PHE A 186
THR A  17
PRO A 154
ILE A  42
 None
 1.14A 2y7wB-1lvmA:
undetectable		 2y7wB-1lvmA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_A_SALA1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 8 SER A  59
PHE A 116
VAL A  57
LEU A  21
 None
 1.03A 3ax7A-1lvmA:
0.0		 3ax7A-1lvmA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		3 / 3 LYS A 141
ILE A 109
THR A 146
 None
 0.85A 4gh8A-1lvmA:
undetectable		 4gh8A-1lvmA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 8 ILE A  18
HIS A 142
HIS A 167
THR A 146
 None
 0.91A 4n16A-1lvmA:
undetectable		 4n16A-1lvmA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 4 THR A  30
LEU A  32
HIS A  46
GLY A 149
 None
 0.61A 5gwyA-1lvmA:
14.2		 5gwyA-1lvmA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		3 / 3 SER A 135
HIS A 214
TYR A 178
 None
 0.94A 5y2tA-1lvmA:
undetectable		 5y2tA-1lvmA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1lvm CATALYTIC DOMAIN OF
THE NUCLEAR
INCLUSION PROTEIN A
(NIA)
(Tobacco
etch
virus) 		4 / 8 GLU A  24
PHE A  64
PHE A  91
MET A  87
 None
 1.09A 5y2tB-1lvmA:
undetectable		 5y2tB-1lvmA:
undetectable