SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lw3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.80A 1c9sT-1lw3A:
undetectable
1c9sU-1lw3A:
undetectable		 1c9sT-1lw3A:
7.46
1c9sU-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.78A 1c9sU-1lw3A:
undetectable
1c9sV-1lw3A:
undetectable		 1c9sU-1lw3A:
7.46
1c9sV-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 483
ILE A 484
PHE A 520
VAL A 487
 None
 0.88A 1fslA-1lw3A:
1.2		 1fslA-1lw3A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.81A 1gtfL-1lw3A:
undetectable
1gtfM-1lw3A:
undetectable		 1gtfL-1lw3A:
7.46
1gtfM-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.78A 1gtfN-1lw3A:
undetectable
1gtfO-1lw3A:
undetectable		 1gtfN-1lw3A:
7.46
1gtfO-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.79A 1gtnA-1lw3A:
undetectable
1gtnK-1lw3A:
undetectable		 1gtnA-1lw3A:
7.46
1gtnK-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.85A 1gtnC-1lw3A:
undetectable
1gtnD-1lw3A:
undetectable		 1gtnC-1lw3A:
7.46
1gtnD-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.81A 1gtnD-1lw3A:
undetectable
1gtnE-1lw3A:
undetectable		 1gtnD-1lw3A:
7.46
1gtnE-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.78A 1gtnE-1lw3A:
undetectable
1gtnF-1lw3A:
undetectable		 1gtnE-1lw3A:
7.46
1gtnF-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.82A 1gtnF-1lw3A:
undetectable
1gtnG-1lw3A:
undetectable		 1gtnF-1lw3A:
7.46
1gtnG-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.80A 1gtnJ-1lw3A:
undetectable
1gtnK-1lw3A:
undetectable		 1gtnJ-1lw3A:
7.46
1gtnK-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.77A 1gtnP-1lw3A:
undetectable
1gtnQ-1lw3A:
undetectable		 1gtnP-1lw3A:
7.46
1gtnQ-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IEP_A_STIA201_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 479
VAL A 358
ILE A 353
ARG A 459
 None
 1.10A 1iepA-1lw3A:
undetectable		 1iepA-1lw3A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 GLY A 420
THR A 428
THR A 424
SER A 271
 PO4  A 655 (-3.6A)
None
None
None
 0.81A 1utdJ-1lw3A:
undetectable
1utdK-1lw3A:
undetectable		 1utdJ-1lw3A:
7.46
1utdK-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 479
VAL A 358
ILE A 353
ARG A 459
 None
 0.98A 2hyyA-1lw3A:
undetectable		 2hyyA-1lw3A:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 4 LEU A 427
THR A 428
ILE A 318
HIS A 416
 None
 1.42A 2jfaB-1lw3A:
0.0		 2jfaB-1lw3A:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WET_B_TRPB650_0
(TRYPTOPHAN
5-HALOGENASE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 10 SER A 324
ILE A 318
HIS A 416
PHE A 350
GLU A 338
 None
 1.49A 2wetB-1lw3A:
0.7		 2wetB-1lw3A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_A_PM6A301_1
(THIOPURINE
S-METHYLTRANSFERASE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 GLY A 130
ALA A 183
LEU A 192
PRO A 185
 None
 1.00A 3bgdA-1lw3A:
undetectable		 3bgdA-1lw3A:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 CYH A 284
THR A 282
LEU A 303
ILE A 316
LEU A 244
 None
 1.43A 3gwxB-1lw3A:
0.0		 3gwxB-1lw3A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 319
SER A 412
ARG A 401
VAL A 406
 None
 1.39A 3jx1A-1lw3A:
undetectable
3jx1B-1lw3A:
undetectable		 3jx1A-1lw3A:
20.42
3jx1B-1lw3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 ALA A 472
ARG A 476
LYS A 156
 None
 0.96A 3kp3B-1lw3A:
0.0		 3kp3B-1lw3A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 479
VAL A 358
ILE A 353
ARG A 459
 None
 1.01A 3ms9A-1lw3A:
undetectable		 3ms9A-1lw3A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_A_STIA1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 479
VAL A 358
ILE A 353
ARG A 459
 None
 0.93A 3mssA-1lw3A:
undetectable		 3mssA-1lw3A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 479
VAL A 358
ILE A 353
ARG A 459
 None
 0.96A 3mssC-1lw3A:
undetectable		 3mssC-1lw3A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 TYR A 209
ILE A 544
PHE A 500
PHE A 551
ILE A 508
 None
 1.31A 3ndiA-1lw3A:
undetectable		 3ndiA-1lw3A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 GLU A 300
TYR A 343
SER A 339
 None
 0.96A 4at0A-1lw3A:
undetectable		 4at0A-1lw3A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 PHE A 319
SER A 412
ARG A 401
VAL A 406
 None
 1.36A 4d32A-1lw3A:
undetectable
4d32B-1lw3A:
0.0		 4d32A-1lw3A:
20.42
4d32B-1lw3A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 LYS A  74
PRO A  77
LYS A 115
 None
 1.42A 4dr5L-1lw3A:
0.0		 4dr5L-1lw3A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 LYS A  74
PRO A  77
LYS A 115
 None
 1.49A 4dr6L-1lw3A:
0.0		 4dr6L-1lw3A:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_A_MIXA1301_1
(DNA TOPOISOMERASE
2-BETA)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 7 GLY A 444
ILE A 442
ASN A 545
GLU A 446
 None
 1.07A 4g0vA-1lw3A:
undetectable		 4g0vA-1lw3A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 ALA A 431
ILE A 353
GLY A 398
ILE A 281
 None
 0.71A 4r21A-1lw3A:
undetectable		 4r21A-1lw3A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5eevL-1lw3A:
undetectable
5eevV-1lw3A:
undetectable		 5eevL-1lw3A:
7.46
5eevV-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5eewL-1lw3A:
undetectable
5eewV-1lw3A:
undetectable		 5eewL-1lw3A:
7.46
5eewV-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5eezL-1lw3A:
undetectable
5eezV-1lw3A:
undetectable		 5eezL-1lw3A:
7.46
5eezV-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5ef1L-1lw3A:
undetectable
5ef1V-1lw3A:
undetectable		 5ef1L-1lw3A:
7.46
5ef1V-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5ef2L-1lw3A:
undetectable
5ef2V-1lw3A:
undetectable		 5ef2L-1lw3A:
7.46
5ef2V-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 8 SER A 271
GLY A 420
THR A 428
THR A 424
 None
PO4  A 655 (-3.6A)
None
None
 0.77A 5ef3L-1lw3A:
undetectable
5ef3V-1lw3A:
undetectable		 5ef3L-1lw3A:
7.46
5ef3V-1lw3A:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 GLY A 334
GLN A 286
LYS A 294
 None
 0.95A 5imsB-1lw3A:
undetectable		 5imsB-1lw3A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A 439
TYR A 215
GLN A 218
 None
 0.98A 5jsdA-1lw3A:
0.0
5jsdB-1lw3A:
0.0		 5jsdA-1lw3A:
21.27
5jsdB-1lw3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		3 / 3 TYR A 439
TYR A 215
GLN A 218
 None
 0.98A 5jsdB-1lw3A:
0.0
5jsdC-1lw3A:
0.0		 5jsdB-1lw3A:
21.27
5jsdC-1lw3A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 VAL A 258
LEU A 270
ARG A 226
ILE A 220
 None
 1.01A 5jw1A-1lw3A:
undetectable		 5jw1A-1lw3A:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_G_SAMG501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 11 LEU A 433
GLY A 437
SER A 429
VAL A 447
GLU A 499
 None
 0.98A 5o96G-1lw3A:
undetectable		 5o96G-1lw3A:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		5 / 12 ILE A 544
SER A 539
LEU A 505
PHE A 445
PHE A 480
 None
 1.43A 6dwnB-1lw3A:
0.0		 6dwnB-1lw3A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 1lw3 MYOTUBULARIN-RELATED
PROTEIN 2
(Homo
sapiens) 		4 / 6 ASN A 545
LEU A 540
SER A 539
PHE A 520
 None
 1.10A 6ekuA-1lw3A:
0.0		 6ekuA-1lw3A:
20.85