SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lwh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_B_803B311_1
(ANTIGEN CD11A (P180))		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 VAL A  86
LEU A  32
VAL A  29
LEU A  42
 None
 0.88A 1cqpA-1lwhA:
undetectable
1cqpB-1lwhA:
undetectable		 1cqpA-1lwhA:
17.70
1cqpB-1lwhA:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 HIS A  52
TYR A  54
ASP A 186
ALA A 187
HIS A 277
ASP A 278
 None
 0.79A 1dedA-1lwhA:
32.2		 1dedA-1lwhA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 HIS A  52
TYR A  54
ARG A 184
ASP A 186
ALA A 187
GLU A 216
 None
 0.76A 1dedB-1lwhA:
32.8		 1dedB-1lwhA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		7 / 12 HIS A  52
TYR A  54
ARG A 184
ASP A 186
ALA A 187
HIS A 277
ASP A 278
 None
 0.63A 1dedB-1lwhA:
32.8		 1dedB-1lwhA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_K_AG2K7002_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 GLU A  34
LEU A 377
LEU A 316
GLY A 313
 None
 0.76A 1mt1H-1lwhA:
undetectable
1mt1K-1lwhA:
0.0		 1mt1H-1lwhA:
13.44
1mt1K-1lwhA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_D_AG2D7015_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 GLU A  34
LEU A 377
LEU A 316
GLY A 313
 None
 0.88A 1n13D-1lwhA:
undetectable
1n13E-1lwhA:
0.0		 1n13D-1lwhA:
13.44
1n13E-1lwhA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_F_AG2F7016_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 8 LEU A 377
LEU A 316
GLY A 313
GLU A  34
 None
 0.87A 1n13A-1lwhA:
undetectable
1n13F-1lwhA:
undetectable		 1n13A-1lwhA:
9.70
1n13F-1lwhA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_H_AG2H7012_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 6 GLU A  34
LEU A 377
LEU A 316
GLY A 313
 None
 0.84A 1n13H-1lwhA:
0.0
1n13K-1lwhA:
0.0		 1n13H-1lwhA:
13.44
1n13K-1lwhA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_J_AG2J7013_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 LEU A 377
LEU A 316
GLY A 313
GLU A  34
 None
 0.88A 1n13G-1lwhA:
0.0
1n13J-1lwhA:
undetectable		 1n13G-1lwhA:
9.70
1n13J-1lwhA:
13.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB8_0
(GRAMICIDIN D)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 VAL A  19
VAL A   8
TRP A 348
 CA  A 914 (-4.2A)
None
None
 0.83A 1w5uA-1lwhA:
undetectable
1w5uB-1lwhA:
undetectable		 1w5uA-1lwhA:
7.03
1w5uB-1lwhA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 9 PHE A  79
VAL A  40
LEU A  42
PHE A  46
LEU A  25
 None
 1.28A 1wrkA-1lwhA:
undetectable
1wrkB-1lwhA:
undetectable		 1wrkA-1lwhA:
12.39
1wrkB-1lwhA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRK_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 5 PHE A 205
LEU A  90
PHE A 201
MET A 191
 None
 0.92A 1wrkB-1lwhA:
undetectable		 1wrkB-1lwhA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 PHE A 205
LEU A  90
PHE A 201
MET A 191
 None
 0.93A 1wrlA-1lwhA:
undetectable
1wrlB-1lwhA:
undetectable		 1wrlA-1lwhA:
12.39
1wrlB-1lwhA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_C_TFPC208_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 5 PHE A 205
LEU A  90
PHE A 201
MET A 191
 None
 0.97A 1wrlC-1lwhA:
undetectable		 1wrlC-1lwhA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA6_A_SCKA902_1
(ACETYLCHOLINESTERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 10 ASN A 276
GLU A 315
LEU A  35
LEU A  32
TYR A  31
 None
 1.35A 2ha6A-1lwhA:
undetectable		 2ha6A-1lwhA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_B_017B203_1
(HIV-1 PROTEASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 GLU A 343
TRP A 336
ARG A  12
GLY A  14
 None
 1.29A 2hs1B-1lwhA:
undetectable		 2hs1B-1lwhA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_C_DVAC8_0
(GRAMICIDIN D)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 VAL A   8
TRP A 348
VAL A  19
 None
None
CA  A 914 (-4.2A)
 0.77A 2izqC-1lwhA:
undetectable
2izqD-1lwhA:
undetectable		 2izqC-1lwhA:
7.03
2izqD-1lwhA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 LEU A  32
LEU A 309
PHE A  11
 None
 0.71A 2pgrA-1lwhA:
3.9		 2pgrA-1lwhA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 5 THR A 239
THR A 303
HIS A 419
LEU A 296
 None
 1.34A 2zj0A-1lwhA:
undetectable		 2zj0A-1lwhA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.87A 3aicA-1lwhA:
5.1		 3aicA-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.95A 3aicB-1lwhA:
3.1		 3aicB-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		7 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
TYR A  54
 None
 0.89A 3aicC-1lwhA:
5.6		 3aicC-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.97A 3aicD-1lwhA:
7.4		 3aicD-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.95A 3aicE-1lwhA:
4.2		 3aicE-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.96A 3aicF-1lwhA:
7.2		 3aicF-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.90A 3aicG-1lwhA:
7.3		 3aicG-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		6 / 12 ARG A 184
ASP A 186
ALA A 187
GLU A 216
HIS A 277
ASP A 278
 None
 0.96A 3aicH-1lwhA:
7.3		 3aicH-1lwhA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 4 ARG A   9
ASP A 314
GLY A 320
THR A 327
 None
 1.47A 3k4vB-1lwhA:
undetectable		 3k4vB-1lwhA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 ILE A  37
LEU A  32
LEU A  25
VAL A  45
 None
 1.00A 3r9vA-1lwhA:
undetectable
3r9vB-1lwhA:
undetectable		 3r9vA-1lwhA:
21.65
3r9vB-1lwhA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 LEU A 175
HIS A 174
MET A 178
 None
 0.86A 3thrD-1lwhA:
undetectable		 3thrD-1lwhA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 LYS A 437
LYS A 434
PRO A 435
 None
 1.05A 4dv1L-1lwhA:
0.0		 4dv1L-1lwhA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_1
(CATECHOL
O-METHYLTRANSFERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 5 GLY A 287
TYR A 322
SER A 280
GLU A 286
 None
 1.28A 4xueA-1lwhA:
undetectable		 4xueA-1lwhA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 12 ARG A 184
ASP A 186
GLU A 216
HIS A 277
ASP A 278
 None
 0.60A 5csyB-1lwhA:
20.4		 5csyB-1lwhA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 5 PRO A 308
HIS A 375
LEU A 404
PHE A 289
 None
 1.48A 5igjA-1lwhA:
undetectable		 5igjA-1lwhA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 9 VAL A   8
LEU A  25
PHE A  79
VAL A  40
ILE A   6
 None
 1.17A 5om2A-1lwhA:
undetectable
5om2B-1lwhA:
undetectable		 5om2A-1lwhA:
11.87
5om2B-1lwhA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 9 LYS A 293
ILE A 294
ILE A 298
LEU A 301
 None
 0.82A 5vkqB-1lwhA:
0.0
5vkqC-1lwhA:
0.0		 5vkqB-1lwhA:
13.65
5vkqC-1lwhA:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 VAL A 405
TYR A 406
GLU A 429
 None
 0.86A 5zmqD-1lwhA:
undetectable
5zmqE-1lwhA:
undetectable		 5zmqD-1lwhA:
18.20
5zmqE-1lwhA:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA609_0
(ALPHA-AMYLASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 LYS A  63
GLY A  53
ASP A 278
TYR A  54
 None
 1.11A 6ag0A-1lwhA:
23.6		 6ag0A-1lwhA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 12 TYR A  54
HIS A  94
ASP A 186
HIS A 277
ASP A 278
 None
 0.46A 6ag0A-1lwhA:
23.6		 6ag0A-1lwhA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC609_0
(ALPHA-AMYLASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 7 LYS A  63
GLY A  53
ASP A 278
TYR A  54
 None
 1.15A 6ag0C-1lwhA:
23.6		 6ag0C-1lwhA:
10.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 GLU A 328
ASP A 332
PRO A 333
 None
 0.80A 6berA-1lwhA:
undetectable		 6berA-1lwhA:
3.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		3 / 3 LEU A 301
SER A 299
PHE A 302
 None
 0.67A 6fgcA-1lwhA:
undetectable		 6fgcA-1lwhA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD4_B_STIB602_1
(TYROSINE-PROTEIN
KINASE ABL1)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 6 LEU A 206
VAL A 263
PHE A 185
GLY A 182
 None
 1.01A 6hd4B-1lwhA:
undetectable		 6hd4B-1lwhA:
12.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_A_FK5A201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 12 ARG A 281
VAL A 362
ILE A  37
PHE A  11
ILE A 294
 None
 1.31A 6mkeA-1lwhA:
undetectable
6mkeD-1lwhA:
undetectable		 6mkeA-1lwhA:
10.98
6mkeD-1lwhA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_B_FK5B201_0
(PEPTIDYLPROLYL
ISOMERASE)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		5 / 12 ARG A 281
VAL A 362
ILE A  37
PHE A  11
ILE A 294
 None
 1.30A 6mkeB-1lwhA:
undetectable
6mkeC-1lwhA:
undetectable		 6mkeB-1lwhA:
10.98
6mkeC-1lwhA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1lwh 4-ALPHA-GLUCANOTRANS
FERASE
(Thermotoga
maritima) 		4 / 8 TRP A 131
HIS A 190
GLU A 216
ASP A 186
 None
 1.22A 6mn4C-1lwhA:
undetectable		 6mn4C-1lwhA:
19.55