SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_B_SAMB402_1
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 5 VAL B 455
SER B 466
ASP B 333
GLN B 274
 None
 1.29A 1n2xB-1lwuB:
undetectable		 1n2xB-1lwuB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		3 / 3 GLU C 271
ASN C 317
TRP C 208
 None
 1.16A 1r15C-1lwuC:
undetectable		 1r15C-1lwuC:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		3 / 3 GLU C 271
ASN C 317
TRP C 208
 None
 1.06A 1r15F-1lwuC:
undetectable		 1r15F-1lwuC:
20.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 11 GLY B 420
TYR B 290
ASN B 282
GLU B 311
PHE B 283
 None
 1.47A 2fl5A-1lwuB:
0.0
2fl5B-1lwuB:
0.7
2fl5F-1lwuB:
0.7		 2fl5A-1lwuB:
21.88
2fl5B-1lwuB:
21.74
2fl5F-1lwuB:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 7 TYR C 260
GLY C 290
TYR C 279
ASP C 295
 None
 0.95A 2g72B-1lwuC:
undetectable		 2g72B-1lwuC:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		3 / 3 ARG B 359
GLU B 352
GLN B 394
 None
 0.85A 2p16A-1lwuB:
undetectable		 2p16A-1lwuB:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_E_SAME1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1lwu FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus;
Petromyzon
marinus) 		5 / 12 GLY C 216
ILE B 305
ARG B 223
ASN B 307
GLU C 225
 None
 1.20A 2vdvE-1lwuC:
undetectable		 2vdvE-1lwuC:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDV_F_SAMF1287_0
(TRNA
(GUANINE-N(7)-)-METH
YLTRANSFERASE)		 1lwu FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus;
Petromyzon
marinus) 		5 / 11 GLY C 216
ILE B 305
ARG B 223
ASN B 307
GLU C 225
 None
 1.20A 2vdvF-1lwuC:
undetectable		 2vdvF-1lwuC:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 12 MET B 472
ALA B 430
PHE B 349
GLY B 370
LEU B 374
 None
 1.45A 3aodC-1lwuB:
0.0		 3aodC-1lwuB:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.85A 3bjwB-1lwuB:
undetectable		 3bjwB-1lwuB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.89A 3bjwF-1lwuB:
undetectable		 3bjwF-1lwuB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_3
(PHOSPHOLIPASE A2)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 VAL B 319
ILE B 248
GLY B 229
ARG B 237
 None
 0.79A 3bjwH-1lwuB:
undetectable		 3bjwH-1lwuB:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)		 1lwu FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus;
Petromyzon
marinus) 		4 / 6 LEU C 123
LYS B 199
GLN B 201
GLU B 204
 None
 1.11A 3h5gB-1lwuC:
undetectable
3h5gC-1lwuC:
undetectable		 3h5gB-1lwuC:
5.35
3h5gC-1lwuC:
5.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 PHE B 283
GLY B 434
GLY B 279
PHE B 395
 None
 0.91A 3ko0M-1lwuB:
undetectable
3ko0P-1lwuB:
undetectable		 3ko0M-1lwuB:
13.40
3ko0P-1lwuB:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus;
Petromyzon
marinus) 		3 / 3 ASP C 199
SER C 201
ARG B 223
 None
 1.01A 3loqA-1lwuC:
0.0		 3loqA-1lwuC:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD391_1
(TETX2 PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 11 GLN B 379
MET B 467
ASN B 431
GLY B 462
ASN B 368
 None
 1.38A 4a99D-1lwuB:
undetectable		 4a99D-1lwuB:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		3 / 3 GLY B 339
SER B 340
TRP B 460
 None
 0.92A 4e7cD-1lwuB:
0.0		 4e7cD-1lwuB:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_K_KANK301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 8 ASP C 390
ASP C 247
ASP C 259
ASP C 283
 None
 1.14A 4gkhC-1lwuC:
undetectable
4gkhK-1lwuC:
undetectable		 4gkhC-1lwuC:
22.73
4gkhK-1lwuC:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 8 ASP C 390
ASP C 247
ASP C 259
ASP C 283
 None
 1.14A 4gkiE-1lwuC:
undetectable
4gkiG-1lwuC:
undetectable		 4gkiE-1lwuC:
22.73
4gkiG-1lwuC:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 PHE B 294
TYR B 290
GLN B 274
PHE B 395
 None
 1.45A 4grqA-1lwuB:
0.0
4grqC-1lwuB:
0.0		 4grqA-1lwuB:
17.78
4grqC-1lwuB:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 7 PHE B 294
TYR B 290
TRP B 313
PHE B 395
 None
 1.28A 4grqA-1lwuB:
0.0
4grqC-1lwuB:
0.0		 4grqA-1lwuB:
17.78
4grqC-1lwuB:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 7 PHE C 215
TYR C 211
GLN C 195
PHE C 310
 None
 1.41A 4grqA-1lwuC:
0.0
4grqC-1lwuC:
0.0		 4grqA-1lwuC:
16.90
4grqC-1lwuC:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRQ_C_AVLC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 7 PHE C 215
TYR C 211
TRP C 227
PHE C 310
 None
 1.17A 4grqA-1lwuC:
0.0
4grqC-1lwuC:
0.0		 4grqA-1lwuC:
16.90
4grqC-1lwuC:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_A_HFGA1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		5 / 12 HIS C 196
GLU C 186
PHE C 182
SER C 165
GLY C 190
 None
 1.48A 4hvcA-1lwuC:
undetectable		 4hvcA-1lwuC:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_B_TOPB202_1
(DIHYDROFOLATE
REDUCTASE)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		5 / 12 ALA C 339
PHE C 288
THR C 380
LEU C 244
THR C 303
 None
 1.09A 4km2B-1lwuC:
undetectable		 4km2B-1lwuC:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		3 / 3 ARG B 285
GLU B 311
TYR B 290
 None
 0.98A 4r29D-1lwuB:
0.0		 4r29D-1lwuB:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 7 ILE C 366
LEU C 377
TYR C 352
GLY C 344
 None
 1.04A 4z69A-1lwuC:
undetectable		 4z69A-1lwuC:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA304_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 4 ARG B 285
THR B 289
GLY B 295
PHE B 294
 None
 1.39A 5uunA-1lwuB:
0.0		 5uunA-1lwuB:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		4 / 8 PRO B 476
THR B 271
TRP B 423
PRO B 351
 None
 1.23A 5x2sI-1lwuB:
undetectable
5x2sJ-1lwuB:
undetectable
5x2sK-1lwuB:
undetectable		 5x2sI-1lwuB:
16.90
5x2sJ-1lwuB:
18.27
5x2sK-1lwuB:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 12 TYR B 442
GLY B 434
ASN B 433
ASN B 282
ASP B 453
 None
 1.26A 5yn6A-1lwuB:
undetectable		 5yn6A-1lwuB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 12 TYR B 442
GLY B 434
ASN B 433
ASN B 282
ASP B 453
 None
 1.26A 5yniA-1lwuB:
undetectable		 5yniA-1lwuB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 12 TYR B 442
GLY B 434
ASN B 433
ASN B 282
ASP B 453
 None
 1.29A 5ynmA-1lwuB:
undetectable		 5ynmA-1lwuB:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1lwu FIBRINOGEN BETA
CHAIN
(Petromyzon
marinus) 		5 / 9 GLY B 434
TYR B 424
ASP B 453
GLY B 454
PRO B 432
 None
 1.30A 5zniA-1lwuB:
undetectable		 5zniA-1lwuB:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 1lwu FIBRINOGEN GAMMA
CHAIN
(Petromyzon
marinus) 		4 / 5 THR C 303
HIS C 338
ASP C 362
ARG C 373
 None
 1.43A 6dchA-1lwuC:
undetectable		 6dchA-1lwuC:
22.99