SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1lxy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 LEU A  78
LEU A  75
LEU A 156
ARG A 180
LEU A 403
 None
None
None
CIR  A 500 (-4.0A)
None
 1.39A 1a28B-1lxyA:
undetectable		 1a28B-1lxyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 5 LEU A 127
LEU A 118
SER A 102
LEU A 106
 None
 0.89A 1a4lC-1lxyA:
undetectable		 1a4lC-1lxyA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 SER A 107
GLU A 108
GLU A 109
 None
 0.57A 1eqbD-1lxyA:
undetectable		 1eqbD-1lxyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 SER A 107
GLU A 108
GLU A 109
 None
 0.56A 1eqbB-1lxyA:
undetectable		 1eqbB-1lxyA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 ILE A 362
ALA A 396
PHE A 384
THR A 370
LEU A 374
 None
 0.94A 1og5B-1lxyA:
0.0		 1og5B-1lxyA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 SER A 187
ILE A  11
PHE A   8
VAL A 190
LEU A  78
 None
 0.94A 1qhsA-1lxyA:
undetectable		 1qhsA-1lxyA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 GLY A 228
ASP A 216
ASN A 260
 None
 0.62A 1vq1A-1lxyA:
undetectable		 1vq1A-1lxyA:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOJ_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 7 LEU A  65
GLY A  18
PRO A 402
VAL A  23
ILE A  70
 None
 1.15A 2aojB-1lxyA:
undetectable		 2aojB-1lxyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 LEU A 197
VAL A  73
LEU A  75
VAL A 170
 None
 1.03A 2bdmA-1lxyA:
undetectable		 2bdmA-1lxyA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 SER A 285
ASP A 349
CYH A 398
 None
None
CIR  A 500 (-1.7A)
 1.14A 2br4E-1lxyA:
undetectable		 2br4E-1lxyA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 ALA A 396
VAL A  23
SER A 400
GLY A 363
ILE A 362
 None
 1.20A 2dcfA-1lxyA:
0.0		 2dcfA-1lxyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 VAL A 217
VAL A 227
LEU A 241
THR A 237
 None
 0.92A 2gehA-1lxyA:
undetectable		 2gehA-1lxyA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 7 ARG A 397
LEU A 354
PRO A  28
VAL A  25
 None
 1.20A 2hrcA-1lxyA:
undetectable		 2hrcA-1lxyA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		6 / 12 LEU A  65
GLY A  18
ILE A  17
PRO A 402
VAL A  23
ILE A  70
 None
 1.29A 2q63A-1lxyA:
undetectable		 2q63A-1lxyA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 SER A 211
TYR A 174
HIS A 173
 None
 0.60A 2r2vD-1lxyA:
0.0		 2r2vD-1lxyA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 LEU A  65
ILE A  17
PRO A 402
VAL A  23
ILE A  70
 None
 1.17A 2r5qA-1lxyA:
undetectable		 2r5qA-1lxyA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 LEU A  65
ILE A  17
PRO A 402
VAL A  23
ILE A  70
 None
 1.17A 2r5qC-1lxyA:
undetectable		 2r5qC-1lxyA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 LEU A  78
LEU A  75
LEU A 156
ARG A 180
LEU A 403
 None
None
None
CIR  A 500 (-4.0A)
None
 1.44A 2w8yB-1lxyA:
undetectable		 2w8yB-1lxyA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 PHE A 158
ASN A 155
PHE A  45
 CIR  A 500 ( 3.8A)
CIR  A 500 (-3.6A)
CIR  A 500 ( 4.9A)
 1.07A 2zbuD-1lxyA:
undetectable		 2zbuD-1lxyA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 ALA A 396
VAL A  23
SER A 400
GLY A 363
ILE A 362
 None
 1.20A 3a65A-1lxyA:
0.0		 3a65A-1lxyA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 GLY A 228
THR A 275
ARG A 176
ARG A 232
GLY A 214
 None
None
None
CIR  A 500 (-2.9A)
None
 1.50A 3abmA-1lxyA:
0.0
3abmB-1lxyA:
0.0
3abmT-1lxyA:
0.0		 3abmA-1lxyA:
20.50
3abmB-1lxyA:
19.56
3abmT-1lxyA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 GLY A 228
THR A 275
ARG A 176
ARG A 232
GLY A 214
 None
None
None
CIR  A 500 (-2.9A)
None
 1.50A 3ag1A-1lxyA:
0.0
3ag1B-1lxyA:
0.0
3ag1T-1lxyA:
0.0		 3ag1A-1lxyA:
20.50
3ag1B-1lxyA:
19.56
3ag1T-1lxyA:
12.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_1
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 GLY A 336
ALA A 337
ILE A 330
THR A 346
ILE A 342
 None
 0.91A 3ekxA-1lxyA:
undetectable		 3ekxA-1lxyA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 LEU A  65
GLY A  18
ILE A  17
PRO A 402
ILE A  70
 None
 1.01A 3el0B-1lxyA:
undetectable		 3el0B-1lxyA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 LEU A 156
ILE A 198
LEU A  78
VAL A  79
LEU A  24
 None
 1.11A 3gwxB-1lxyA:
0.0		 3gwxB-1lxyA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA304_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 4 GLN A 307
PRO A 308
VAL A 309
GLU A 310
 None
 1.28A 3huoA-1lxyA:
0.0		 3huoA-1lxyA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_B_BCZB468_1
(NEURAMINIDASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 ARG A 366
GLU A  57
TYR A 157
 TRS  A 601 (-3.5A)
None
None
 0.92A 3k37B-1lxyA:
0.0		 3k37B-1lxyA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_1
(HIV-1 PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		6 / 12 LEU A  65
GLY A  18
ILE A  17
PRO A 402
VAL A  23
ILE A  70
 None
 1.26A 3k4vA-1lxyA:
undetectable		 3k4vA-1lxyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 ASN A 248
ALA A 247
LYS A 249
 None
 1.03A 3runA-1lxyA:
undetectable		 3runA-1lxyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 ASP A  69
ILE A  70
GLY A  18
ILE A  17
ILE A 362
 None
 0.91A 3s43A-1lxyA:
undetectable		 3s43A-1lxyA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		6 / 12 LEU A  65
GLY A  18
ILE A  17
PRO A 402
VAL A  23
ILE A  70
 None
 1.22A 3tl9B-1lxyA:
undetectable		 3tl9B-1lxyA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 THR A 200
LEU A  78
VAL A   3
VAL A 190
PHE A   8
 None
 1.47A 3u9fN-1lxyA:
undetectable
3u9fO-1lxyA:
undetectable		 3u9fN-1lxyA:
21.80
3u9fO-1lxyA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 VAL A 113
VAL A 114
LEU A 118
ASP A 139
 None
 0.68A 3wzeA-1lxyA:
undetectable		 3wzeA-1lxyA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		3 / 3 TRP A 264
TRP A 273
THR A 272
 None
None
CIR  A 500 (-4.5A)
 1.36A 4bboB-1lxyA:
0.0		 4bboB-1lxyA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 PHE A 292
VAL A 261
THR A 351
GLU A  16
THR A 275
 None
 1.17A 4fiaA-1lxyA:
0.0		 4fiaA-1lxyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 PHE A 292
VAL A 261
THR A 351
GLU A  16
THR A 275
 None
 1.17A 4fiaA-1lxyA:
0.0		 4fiaA-1lxyA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J03_A_FVSA603_1
(BIFUNCTIONAL EPOXIDE
HYDROLASE 2)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 ILE A 332
PHE A  61
LEU A  20
LEU A  65
LEU A 277
 None
 1.34A 4j03A-1lxyA:
undetectable		 4j03A-1lxyA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 5 GLU A 183
ARG A 180
PRO A 162
SER A 187
 None
CIR  A 500 (-4.0A)
None
None
 1.19A 4k17B-1lxyA:
undetectable		 4k17B-1lxyA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L39_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 7 LEU A 374
TYR A 353
THR A 370
ILE A 332
THR A 275
 None
 1.48A 4l39B-1lxyA:
undetectable		 4l39B-1lxyA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 ASP A  69
PRO A 358
VAL A 360
ALA A 355
GLY A  18
 None
 1.13A 4mmaA-1lxyA:
undetectable		 4mmaA-1lxyA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 7 GLU A  81
THR A  82
THR A 200
LEU A 403
 None
 1.10A 4pfjA-1lxyA:
undetectable		 4pfjA-1lxyA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Y_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 7 ASN A 260
PHE A 294
TRP A 295
TYR A 297
 None
 1.02A 4v2yB-1lxyA:
0.0		 4v2yB-1lxyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V2Z_B_Y70B151_1
(CEREBLON ISOFORM 4)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 ASN A 260
PHE A 294
TRP A 295
TYR A 297
 None
 1.02A 4v2zB-1lxyA:
undetectable		 4v2zB-1lxyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V30_B_LVYB151_1
(CEREBLON ISOFORM 4)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 ASN A 260
PHE A 294
TRP A 295
TYR A 297
 None
 1.02A 4v30B-1lxyA:
undetectable		 4v30B-1lxyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 GLY A 359
TYR A 284
LEU A 274
PHE A 294
GLY A 317
 None
 1.15A 4ze2A-1lxyA:
0.0		 4ze2A-1lxyA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMK_B_EF2B151_1
(CEREBLON ISOFORM 4)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 7 ASN A 260
PHE A 294
TRP A 295
TYR A 297
 None
 0.99A 5amkB-1lxyA:
undetectable		 5amkB-1lxyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 6 VAL A 190
HIS A 194
LEU A 197
LEU A 403
 None
 1.23A 5hrqB-1lxyA:
undetectable
5hrqI-1lxyA:
undetectable
5hrqJ-1lxyA:
undetectable		 5hrqB-1lxyA:
5.99
5hrqI-1lxyA:
4.36
5hrqJ-1lxyA:
5.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 LEU A  65
GLY A  18
PRO A 402
VAL A  23
ILE A  70
 None
 1.13A 5kr2D-1lxyA:
undetectable		 5kr2D-1lxyA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 6 LEU A 225
ILE A 172
THR A 171
MET A 401
 None
 1.40A 5ljeA-1lxyA:
0.0		 5ljeA-1lxyA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 VAL A 128
PRO A 162
ARG A 125
LEU A  24
GLU A  31
 None
 1.29A 5mqtC-1lxyA:
0.1		 5mqtC-1lxyA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 8 VAL A 217
VAL A 227
LEU A 241
THR A 237
 None
 0.80A 5tt3F-1lxyA:
undetectable		 5tt3F-1lxyA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		4 / 7 SER A 321
ILE A 322
LEU A 318
LEU A 313
 None
 0.75A 5u4sA-1lxyA:
undetectable		 5u4sA-1lxyA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 12 LEU A  24
VAL A 217
SER A 187
PRO A 206
ILE A 172
 None
 1.33A 5uahC-1lxyA:
0.0		 5uahC-1lxyA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 9 LEU A 274
THR A 275
GLY A 350
ILE A 332
PHE A 292
 None
 1.32A 6ebpA-1lxyA:
0.0		 6ebpA-1lxyA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 1lxy ARGININE DEIMINASE
(Mycoplasma
arginini) 		5 / 11 PHE A  45
ILE A  48
LEU A  49
LEU A  44
PRO A 154
 CIR  A 500 ( 4.9A)
None
None
CIR  A 500 (-3.5A)
None
 1.25A 6fgcA-1lxyA:
0.0		 6fgcA-1lxyA:
11.47