SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ly7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 1ly7 FRATAXIN
(Homo
sapiens) 		4 / 6 ASN A 172
TRP A 168
TYR A 205
GLY A 207
 None
 1.33A 1mxdA-1ly7A:
undetectable		 1mxdA-1ly7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 1ly7 FRATAXIN
(Homo
sapiens) 		4 / 7 ASN A 172
TRP A 168
TYR A 205
GLY A 207
 None
 1.32A 1mxgA-1ly7A:
undetectable		 1mxgA-1ly7A:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1ly7 FRATAXIN
(Homo
sapiens) 		4 / 5 GLU A 189
THR A 196
LEU A 198
LEU A 194
 None
 0.92A 1u18B-1ly7A:
0.2		 1u18B-1ly7A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 1ly7 FRATAXIN
(Homo
sapiens) 		5 / 12 LEU A 103
GLY A 207
THR A 102
LEU A 106
GLY A 170
 None
 0.99A 4dc3A-1ly7A:
undetectable		 4dc3A-1ly7A:
13.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 1ly7 FRATAXIN
(Homo
sapiens) 		3 / 3 HIS A 183
VAL A 125
LEU A 132
 None
 0.61A 4m2vA-1ly7A:
undetectable		 4m2vA-1ly7A:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1ly7 FRATAXIN
(Homo
sapiens) 		3 / 3 LEU A 185
TYR A 143
SER A 160
 None
 0.86A 5iktA-1ly7A:
0.0		 5iktA-1ly7A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 1ly7 FRATAXIN
(Homo
sapiens) 		5 / 12 THR A 191
PHE A 110
PHE A 109
LEU A 132
VAL A 134
 None
 1.06A 6a93B-1ly7A:
undetectable		 6a93B-1ly7A:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWV_A_BEZA202_0
(ARA H 8 ALLERGEN)		 1ly7 FRATAXIN
(Homo
sapiens) 		4 / 4 PHE A 120
ASP A 122
LEU A 140
LYS A 135
 None
 1.24A 6awvA-1ly7A:
0.1		 6awvA-1ly7A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1ly7 FRATAXIN
(Homo
sapiens) 		4 / 8 TYR A 118
LEU A 198
VAL A 134
VAL A 125
 None
 1.05A 6cp4A-1ly7A:
0.0		 6cp4A-1ly7A:
15.59