SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m0d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 1m0d ENDODEOXYRIBONUCLEAS
E I
(Escherichia
virus
T7) 		4 / 8 TRP A  70
HIS A  78
PHE A  94
TRP A 129
 None
 1.30A 3v35A-1m0dA:
undetectable		 3v35A-1m0dA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 1m0d ENDODEOXYRIBONUCLEAS
E I
(Escherichia
virus
T7) 		5 / 12 LEU A  58
ILE A  62
ILE A 130
ALA A 127
ALA A 121
 None
 1.12A 4enhA-1m0dA:
undetectable		 4enhA-1m0dA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 1m0d ENDODEOXYRIBONUCLEAS
E I
(Escherichia
virus
T7) 		4 / 6 ILE A  92
GLY A  61
ASN A  60
ILE A  90
 None
 0.96A 5j4nB-1m0dA:
undetectable		 5j4nB-1m0dA:
13.59