SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m0s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_2
(PROTEIN (PROTEASE))		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.97A 1c6zB-1m0sA:
undetectable		 1c6zB-1m0sA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.01A 1fb7A-1m0sA:
undetectable		 1fb7A-1m0sA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_D_ESTD352_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		4 / 6 VAL A 144
GLY A 145
LEU A 170
GLU A 135
 None
 0.98A 1fduD-1m0sA:
undetectable		 1fduD-1m0sA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 LEU A  15
ALA A  38
ALA A  49
ILE A  78
ILE A 116
 None
 0.84A 1fk6A-1m0sA:
undetectable		 1fk6A-1m0sA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 10 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.98A 1muiA-1m0sA:
undetectable		 1muiA-1m0sA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 10 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.94A 2aquA-1m0sA:
undetectable		 2aquA-1m0sA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_1
(HIV-1 PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.03A 2hs1A-1m0sA:
undetectable		 2hs1A-1m0sA:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 PHE A 130
ALA A  52
PHE A 113
ALA A 107
GLY A 197
 None
 1.25A 2ve3B-1m0sA:
0.0		 2ve3B-1m0sA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		4 / 8 LEU A  15
GLN A  16
PHE A  35
LEU A  39
 None
 0.88A 3asoC-1m0sA:
undetectable
3asoJ-1m0sA:
undetectable		 3asoC-1m0sA:
19.57
3asoJ-1m0sA:
14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 9 PHE A  35
VAL A  32
GLY A  82
TYR A  79
GLY A  27
 None
None
CIT  A 501 ( 4.6A)
None
None
 1.12A 3csjB-1m0sA:
undetectable		 3csjB-1m0sA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 8 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.11A 3ekpA-1m0sA:
undetectable		 3ekpA-1m0sA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 11 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.09A 3ektD-1m0sA:
undetectable		 3ektD-1m0sA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.91A 3ekwB-1m0sA:
undetectable		 3ekwB-1m0sA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 11 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.95A 3el1A-1m0sA:
undetectable		 3el1A-1m0sA:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.89A 3ndwA-1m0sA:
undetectable		 3ndwA-1m0sA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDX_A_RITA100_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.89A 3ndxA-1m0sA:
undetectable		 3ndxA-1m0sA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		4 / 7 ALA A  14
VAL A  24
VAL A  18
LEU A  15
 None
 0.60A 3o14A-1m0sA:
undetectable		 3o14A-1m0sA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.03A 3pwmA-1m0sA:
undetectable		 3pwmA-1m0sA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 8 ILE A 116
LYS A 112
ILE A  78
PHE A 113
GLY A 203
 None
 1.10A 4hdlA-1m0sA:
0.0		 4hdlA-1m0sA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 0.99A 4hlaA-1m0sA:
undetectable		 4hlaA-1m0sA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJV_A_RITA500_1
(PROTEASE)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ALA A  98
GLY A 197
ILE A  93
ILE A 169
 CIT  A 501 (-3.1A)
None
None
None
None
 1.03A 4njvA-1m0sA:
undetectable		 4njvA-1m0sA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A  97
ILE A  93
GLY A 197
SER A  28
PHE A 199
 CIT  A 501 (-3.1A)
None
None
None
None
 1.26A 4obwC-1m0sA:
undetectable		 4obwC-1m0sA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 10 ASN A 196
VAL A 144
LEU A 148
LEU A 170
VAL A 172
 None
 1.05A 4po0A-1m0sA:
undetectable		 4po0A-1m0sA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_F_SAMF301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 GLY A 197
GLY A  95
GLY A  96
ALA A 200
LEU A 126
 None
CIT  A 501 (-3.7A)
CIT  A 501 (-3.3A)
None
None
 0.77A 5c0oF-1m0sA:
2.9		 5c0oF-1m0sA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 VAL A 106
SER A  56
VAL A  67
GLY A  48
ALA A  49
 None
 1.12A 5iktA-1m0sA:
undetectable		 5iktA-1m0sA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		5 / 12 VAL A 106
SER A  56
VAL A  67
GLY A  48
ALA A  49
 None
 1.08A 5iktB-1m0sA:
undetectable		 5iktB-1m0sA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGL_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		3 / 3 VAL A 168
VAL A 136
GLN A 143
 None
 0.69A 5qglA-1m0sA:
undetectable		 5qglA-1m0sA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		3 / 3 VAL A 168
VAL A 136
GLN A 143
 None
 0.70A 5qhgA-1m0sA:
undetectable		 5qhgA-1m0sA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		4 / 8 GLY A 197
ARG A 158
ASP A 171
ASP A  84
 None
None
None
CIT  A 501 (-2.8A)
 0.98A 5vlmB-1m0sA:
0.0		 5vlmB-1m0sA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 1m0s RIBOSE-5-PHOSPHATE
ISOMERASE A
(Haemophilus
influenzae) 		4 / 8 ILE A 169
ARG A 158
VAL A 172
ASP A  84
 None
None
None
CIT  A 501 (-2.8A)
 0.97A 5vlmF-1m0sA:
0.4		 5vlmF-1m0sA:
23.08