SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m0v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 6 ILE A  44
SER A  51
ASN A  34
THR A  24
 None
 1.09A 1h7xA-1m0vA:
undetectable		 1h7xA-1m0vA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 6 ILE A  44
SER A  51
ASN A  34
THR A  24
 None
 1.09A 1h7xB-1m0vA:
undetectable		 1h7xB-1m0vA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 6 ILE A  44
SER A  51
ASN A  34
THR A  24
 None
 1.10A 1h7xC-1m0vA:
undetectable		 1h7xC-1m0vA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 6 ILE A  44
SER A  51
ASN A  34
THR A  24
 None
 1.09A 1h7xD-1m0vA:
undetectable		 1h7xD-1m0vA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		5 / 12 VAL A  66
LEU A   8
VAL A 115
LEU A  76
PHE A  55
 None
 1.25A 2jn3A-1m0vA:
undetectable		 2jn3A-1m0vA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_D_ACHD1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 8 THR A 109
GLN A 107
ASP A 112
SER A  79
 None
 1.20A 2xz5C-1m0vA:
undetectable
2xz5D-1m0vA:
undetectable		 2xz5C-1m0vA:
22.27
2xz5D-1m0vA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWU_A_SREA801_1
(TRANSPORTER)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		5 / 12 LEU A  15
LEU A 110
ALA A 113
PHE A  55
LEU A   8
 None
 1.30A 3gwuA-1m0vA:
undetectable		 3gwuA-1m0vA:
11.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		3 / 3 ASN A  34
ALA A  33
LYS A  35
 None
 0.99A 3runA-1m0vA:
undetectable		 3runA-1m0vA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 4 ALA A 119
VAL A 115
ASP A  72
LEU A  90
 None
 1.32A 4e7gA-1m0vA:
0.4		 4e7gA-1m0vA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HXY_B_ACAB502_1
(PLM1)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		4 / 7 VAL A  63
SER A 102
LEU A  68
ASP A  72
 None
 0.98A 4hxyB-1m0vA:
undetectable		 4hxyB-1m0vA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		3 / 3 ARG A  49
GLU A  36
ASN A  34
 None
 0.91A 4imaD-1m0vA:
undetectable		 4imaD-1m0vA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1m0v PROTEIN-TYROSINE
PHOSPHATASE YOPH
(Yersinia
pseudotuberculos
is) 		3 / 3 ARG A  49
GLU A  36
ASN A  34
 None
 0.90A 4ip7D-1m0vA:
undetectable		 4ip7D-1m0vA:
14.36