SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m1c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 VAL A 464
VAL A 466
TRP A 313
None
0.72A 1av2C-1m1cA:
undetectable
1av2D-1m1cA:
undetectable
1av2C-1m1cA:
1.76
1av2D-1m1cA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 ASP A 554
ASP A 556
LYS A 506
None
1.09A 1lqtB-1m1cA:
undetectable
1lqtB-1m1cA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 ASP A 554
ASP A 556
LYS A 506
None
1.06A 1lquB-1m1cA:
undetectable
1lquB-1m1cA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 ILE A  86
ALA A 108
LEU A  93
ARG A 243
LEU A 335
None
1.13A 1rx3A-1m1cA:
undetectable
1rx3A-1m1cA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX8_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 ILE A  86
ALA A 108
LEU A  93
ARG A 243
LEU A 335
None
1.05A 1rx8A-1m1cA:
undetectable
1rx8A-1m1cA:
13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 VAL A 464
VAL A 466
TRP A 313
None
0.73A 1w5uC-1m1cA:
undetectable
1w5uD-1m1cA:
undetectable
1w5uC-1m1cA:
1.76
1w5uD-1m1cA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 SER A 143
VAL A  56
LEU A 227
None
0.67A 1yajG-1m1cA:
0.0
1yajG-1m1cA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 THR A 531
VAL A 557
GLY A 555
THR A 384
None
0.95A 2a1mA-1m1cA:
undetectable
2a1mA-1m1cA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 SER A 424
GLU A  71
ASP A  81
None
0.87A 2avdB-1m1cA:
undetectable
2avdB-1m1cA:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 PRO A 100
GLY A 101
ASN A 102
SER A 192
PHE A 334
None
1.21A 2b9eA-1m1cA:
undetectable
2b9eA-1m1cA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 VAL A 466
TRP A 313
VAL A 464
None
0.63A 2izqA-1m1cA:
undetectable
2izqB-1m1cA:
undetectable
2izqA-1m1cA:
1.76
2izqB-1m1cA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 ARG A  45
ASN A 483
THR A 546
None
0.85A 2q63A-1m1cA:
0.0
2q63A-1m1cA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA502_0
(CHORISMATE SYNTHASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 GLY A 397
ASP A 396
SER A 393
None
0.72A 2qhfA-1m1cA:
undetectable
2qhfA-1m1cA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R2V_D_ACTD36_0
(GCN4 LEUCINE ZIPPER)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 SER A 106
TYR A 109
HIS A 107
None
0.82A 2r2vD-1m1cA:
undetectable
2r2vD-1m1cA:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 GLY A 422
GLU A 630
GLY A 629
ILE A 626
LEU A 420
None
1.06A 2x1lB-1m1cA:
undetectable
2x1lB-1m1cA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 7 GLN A 416
VAL A 476
ILE A 473
GLY A 415
THR A 414
None
1.29A 2xrzB-1m1cA:
undetectable
2xrzB-1m1cA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 8 LEU A 123
VAL A 211
LEU A 215
VAL A 203
LEU A 201
None
1.40A 3kp6A-1m1cA:
0.3
3kp6B-1m1cA:
undetectable
3kp6A-1m1cA:
14.40
3kp6B-1m1cA:
14.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 VAL A 464
VAL A 466
TRP A 313
None
0.78A 3l8lA-1m1cA:
undetectable
3l8lB-1m1cA:
undetectable
3l8lA-1m1cA:
1.76
3l8lB-1m1cA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 VAL A 464
VAL A 466
TRP A 313
None
0.84A 3l8lC-1m1cA:
undetectable
3l8lD-1m1cA:
undetectable
3l8lC-1m1cA:
1.76
3l8lD-1m1cA:
1.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 PHE A 362
PHE A  26
ALA A 600
LEU A 136
None
1.11A 3t3sC-1m1cA:
undetectable
3t3sC-1m1cA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_C_RTZC2_1
(CYTOCHROME P450 2D6)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 10 LEU A 360
THR A 363
VAL A   5
GLU A 359
LEU A 613
None
1.35A 3tbgC-1m1cA:
0.0
3tbgC-1m1cA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1003_1
(HEMOLYTIC LECTIN
CEL-III)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 4 ASP A 392
GLU A 395
GLY A 397
TYR A 394
None
1.36A 3w9tA-1m1cA:
0.0
3w9tA-1m1cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB507_1
(HEMOLYTIC LECTIN
CEL-III)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 4 ASP A 392
GLU A 395
GLY A 397
TYR A 394
None
1.37A 3w9tB-1m1cA:
0.0
3w9tB-1m1cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 5 ASP A 392
GLU A 395
GLY A 397
TYR A 394
None
1.36A 3w9tD-1m1cA:
0.0
3w9tD-1m1cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE503_1
(HEMOLYTIC LECTIN
CEL-III)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 4 ASP A 392
GLU A 395
GLY A 397
TYR A 394
None
1.35A 3w9tE-1m1cA:
0.0
3w9tE-1m1cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF502_1
(HEMOLYTIC LECTIN
CEL-III)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 4 ASP A 392
GLU A 395
GLY A 397
TYR A 394
None
1.36A 3w9tF-1m1cA:
0.0
3w9tF-1m1cA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.17A 3wipA-1m1cA:
undetectable
3wipB-1m1cA:
undetectable
3wipA-1m1cA:
15.97
3wipB-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.16A 3wipB-1m1cA:
undetectable
3wipC-1m1cA:
undetectable
3wipB-1m1cA:
15.97
3wipC-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.13A 3wipC-1m1cA:
undetectable
3wipD-1m1cA:
undetectable
3wipC-1m1cA:
15.97
3wipD-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_D_ACHD301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.15A 3wipD-1m1cA:
0.0
3wipE-1m1cA:
0.0
3wipD-1m1cA:
15.97
3wipE-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_E_ACHE301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 ARG A 517
TYR A 485
TRP A 510
THR A 546
None
1.16A 3wipA-1m1cA:
undetectable
3wipE-1m1cA:
0.0
3wipA-1m1cA:
15.97
3wipE-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.15A 3wipF-1m1cA:
undetectable
3wipG-1m1cA:
0.0
3wipF-1m1cA:
15.97
3wipG-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TYR A 485
TRP A 510
THR A 546
ARG A 517
None
1.17A 3wipG-1m1cA:
0.0
3wipH-1m1cA:
0.0
3wipG-1m1cA:
15.97
3wipH-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 ARG A 517
TYR A 485
TRP A 510
THR A 546
None
1.15A 3wipF-1m1cA:
0.0
3wipJ-1m1cA:
0.0
3wipF-1m1cA:
15.97
3wipJ-1m1cA:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 SER A  67
ASN A 633
GLU A 403
ASP A 425
None
1.11A 4d33B-1m1cA:
0.0
4d33B-1m1cA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 PRO A 267
VAL A 271
MET A 272
ALA A 275
None
0.41A 4lb2A-1m1cA:
0.0
4lb2A-1m1cA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 VAL A  32
TYR A  47
PHE A 474
SER A 469
THR A 591
None
1.26A 4mm4A-1m1cA:
0.0
4mm4A-1m1cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 VAL A  32
TYR A  47
PHE A 474
SER A 469
THR A 591
None
1.26A 4mm4B-1m1cA:
0.0
4mm4B-1m1cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 10 VAL A  32
TYR A  47
PHE A 474
SER A 469
THR A 591
None
1.23A 4mm7A-1m1cA:
0.0
4mm7A-1m1cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 VAL A  32
TYR A  47
PHE A 474
SER A  50
THR A 591
None
1.07A 4mm8A-1m1cA:
0.0
4mm8A-1m1cA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 5 GLN A 235
SER A 219
ASP A 252
ASP A 258
None
1.48A 4qtuB-1m1cA:
undetectable
4qtuB-1m1cA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZC_D_EF2D505_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.91A 4tzcB-1m1cA:
undetectable
4tzcD-1m1cA:
undetectable
4tzcB-1m1cA:
8.51
4tzcD-1m1cA:
8.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_B_Y70B505_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.89A 4tzuB-1m1cA:
undetectable
4tzuC-1m1cA:
undetectable
4tzuB-1m1cA:
8.41
4tzuC-1m1cA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TZU_C_Y70C504_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.87A 4tzuB-1m1cA:
undetectable
4tzuC-1m1cA:
undetectable
4tzuB-1m1cA:
8.41
4tzuC-1m1cA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 SER A  21
ASP A 165
GLY A 145
GLY A  24
ALA A 600
None
1.29A 4ubeA-1m1cA:
undetectable
4ubeA-1m1cA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 9 GLY A 145
THR A 225
GLN A 599
LEU A 136
LEU A 133
None
1.48A 5fhzB-1m1cA:
0.0
5fhzB-1m1cA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 ARG A 517
ASN A 541
ASP A 152
None
0.92A 5gwxA-1m1cA:
undetectable
5gwxA-1m1cA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 GLY A  57
LEU A 227
GLY A  24
ASP A 146
THR A  54
None
1.17A 5hg0A-1m1cA:
undetectable
5hg0A-1m1cA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 SER A 337
ILE A  86
ALA A  85
LEU A  84
None
0.81A 5te8B-1m1cA:
undetectable
5te8B-1m1cA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
3 / 3 ILE A 322
VAL A 320
PRO A  59
None
0.56A 5uunA-1m1cA:
0.1
5uunA-1m1cA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TYR A 231
VAL A  61
LEU A 296
ILE A 322
None
0.92A 5v0vA-1m1cA:
0.0
5v0vA-1m1cA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
5 / 12 LEU A 410
THR A 414
VAL A 476
ASN A   8
THR A 346
None
1.39A 5v1tA-1m1cA:
undetectable
5v1tA-1m1cA:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
6 / 12 GLY A 397
GLY A 644
GLY A 646
THR A 641
ASP A 392
ILE A 390
None
1.39A 5wz2C-1m1cA:
undetectable
5wz2C-1m1cA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_G_EF2G501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.88A 5yizG-1m1cA:
undetectable
5yizY-1m1cA:
undetectable
5yizG-1m1cA:
7.65
5yizY-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_K_EF2K501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.92A 5yizk-1m1cA:
0.0
5yizt-1m1cA:
undetectable
5yizk-1m1cA:
7.65
5yizt-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_T_EF2T501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.87A 5yizk-1m1cA:
0.0
5yizt-1m1cA:
undetectable
5yizk-1m1cA:
7.65
5yizt-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YIZ_Y_EF2Y501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.92A 5yizG-1m1cA:
undetectable
5yizY-1m1cA:
undetectable
5yizG-1m1cA:
7.65
5yizY-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_G_EF2G501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.90A 5yj0G-1m1cA:
0.0
5yj0Y-1m1cA:
0.0
5yj0G-1m1cA:
7.65
5yj0Y-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_K_EF2K501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.91A 5yj0k-1m1cA:
undetectable
5yj0t-1m1cA:
undetectable
5yj0k-1m1cA:
7.65
5yj0t-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_T_EF2T501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.89A 5yj0k-1m1cA:
0.0
5yj0t-1m1cA:
0.0
5yj0k-1m1cA:
7.65
5yj0t-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ0_Y_EF2Y501_1
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.92A 5yj0G-1m1cA:
undetectable
5yj0Y-1m1cA:
undetectable
5yj0G-1m1cA:
7.65
5yj0Y-1m1cA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_G_6ELG501_0
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.88A 5yj1G-1m1cA:
0.0
5yj1Y-1m1cA:
undetectable
5yj1G-1m1cA:
8.33
5yj1Y-1m1cA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_K_6ELK501_0
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 HIS A 547
TRP A 510
PHE A 386
TRP A 545
None
0.93A 5yj1k-1m1cA:
undetectable
5yj1t-1m1cA:
0.0
5yj1k-1m1cA:
8.33
5yj1t-1m1cA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.88A 5yj1k-1m1cA:
undetectable
5yj1t-1m1cA:
undetectable
5yj1k-1m1cA:
8.33
5yj1t-1m1cA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_Y_6ELY501_0
(PROTEIN CEREBLON)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 7 TRP A 545
HIS A 547
TRP A 510
PHE A 386
None
0.92A 5yj1G-1m1cA:
0.0
5yj1Y-1m1cA:
0.0
5yj1G-1m1cA:
8.33
5yj1Y-1m1cA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 9 VAL A 155
HIS A 154
ASP A 152
VAL A 304
None
0.97A 6c2mD-1m1cA:
undetectable
6c2mD-1m1cA:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 4 HIS A 316
VAL A 464
LEU A 433
ALA A 312
None
1.42A 6d8pB-1m1cA:
undetectable
6d8pB-1m1cA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)
1m1c MAJOR COAT PROTEIN
(Saccharomyces
cerevisiae
virus
L-A)
4 / 8 ASP A 543
SER A 469
GLY A 601
VAL A 598
None
0.98A 6giqL-1m1cA:
0.0
6giqP-1m1cA:
0.0
6giqT-1m1cA:
0.0
6giqL-1m1cA:
21.06
6giqP-1m1cA:
16.64
6giqT-1m1cA:
6.76