SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m1j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
5 / 12 THR C 259
ALA C 260
ASP C 261
MET C 379
ILE C 367
None
0.99A 1errA-1m1jC:
undetectable
1errA-1m1jC:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus;
Gallus
gallus)
5 / 11 LEU B 173
VAL B 176
MET A 194
LEU A 186
GLN A 188
None
1.09A 1kt6A-1m1jB:
1.0
1kt6A-1m1jB:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus;
Gallus
gallus)
5 / 11 LEU B 173
VAL B 176
MET A 194
LEU A 186
GLN A 188
None
1.07A 1kt7A-1m1jB:
0.7
1kt7A-1m1jB:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 8 SER B 455
ILE B 257
GLU B 295
GLY B 294
None
0.94A 1meiA-1m1jB:
undetectable
1meiA-1m1jB:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1m1j FIBRINOGEN ALPHA
SUBUNIT

(Gallus
gallus)
3 / 3 ILE A 120
LEU A 123
VAL A 127
None
0.37A 1mz9B-1m1jA:
4.5
1mz9B-1m1jA:
7.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
3 / 3 LEU B 173
VAL B 176
LEU B 180
None
0.40A 1mz9B-1m1jB:
3.5
1mz9B-1m1jB:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_3
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
3 / 3 THR C  36
LEU C  40
LEU C  47
None
0.39A 1mz9C-1m1jC:
3.8
1mz9C-1m1jC:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_A_SAMA1217_0
(CATECHOL
O-METHYLTRANSFERASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 MET B 451
GLY B 446
TYR B 449
TYR B 421
SER B 362
None
1.37A 2cl5A-1m1jB:
undetectable
2cl5A-1m1jB:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus;
Gallus
gallus)
3 / 3 SER B 179
THR A 187
GLN A 183
None
0.80A 2fk8A-1m1jB:
undetectable
2fk8A-1m1jB:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 6 LEU A 151
ASN B 266
GLN B 194
ILE B 191
None
1.23A 2jn3A-1m1jA:
undetectable
2jn3A-1m1jA:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 7 ILE B 309
ARG B 214
GLY B 253
TRP B 254
None
1.08A 2pnjB-1m1jB:
undetectable
2pnjB-1m1jB:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ILE B 303
GLY B 299
GLY B 277
SER B 455
LEU B 256
None
1.05A 2qmmA-1m1jB:
undetectable
2qmmA-1m1jB:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_A_DMOA700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))
1m1j FIBRINOGEN ALPHA
SUBUNIT

(Gallus
gallus)
4 / 6 ASP A 171
PHE A 170
ASP A 156
TYR A 172
None
1.32A 2todA-1m1jA:
undetectable
2todB-1m1jA:
undetectable
2todA-1m1jA:
20.08
2todB-1m1jA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TOD_D_DMOD700_1
(PROTEIN (ORNITHINE
DECARBOXYLASE))
1m1j FIBRINOGEN ALPHA
SUBUNIT

(Gallus
gallus)
4 / 5 ASP A 156
TYR A 172
ASP A 171
PHE A 170
None
1.34A 2todC-1m1jA:
undetectable
2todD-1m1jA:
undetectable
2todC-1m1jA:
20.08
2todD-1m1jA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_1
(WNT INHIBITORY
FACTOR 1)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 5 ILE C 145
PRO C 220
VAL C 267
PHE C 226
None
1.27A 2ygnA-1m1jC:
0.0
2ygnA-1m1jC:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 7 PHE C 290
ARG C 247
MET C 384
THR C 383
None
1.00A 3ag2N-1m1jC:
undetectable
3ag2W-1m1jC:
2.8
3ag2N-1m1jC:
19.62
3ag2W-1m1jC:
8.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWM_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 MET B 451
GLY B 446
TYR B 449
TYR B 421
SER B 362
None
1.32A 3bwmA-1m1jB:
undetectable
3bwmA-1m1jB:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 MET B 451
GLY B 446
TYR B 449
TYR B 421
SER B 362
None
1.35A 3bwyA-1m1jB:
undetectable
3bwyA-1m1jB:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
5 / 12 LEU A 211
ARG B 137
LEU A  95
LEU B 130
ILE C  67
None
1.07A 3gwxB-1m1jA:
undetectable
3gwxB-1m1jA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 6 GLN B 185
LEU B 187
GLU B 188
LEU C 124
None
0.90A 3h5gA-1m1jB:
undetectable
3h5gC-1m1jB:
undetectable
3h5gA-1m1jB:
5.29
3h5gC-1m1jB:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_B_LEIB16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 5 LEU C 124
LYS B 183
GLN B 185
LEU B 187
None
0.86A 3h5gA-1m1jC:
undetectable
3h5gB-1m1jC:
undetectable
3h5gA-1m1jC:
7.64
3h5gB-1m1jC:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 6 LYS B 183
LEU B 187
LEU A 151
GLU A 152
None
1.03A 3h5gB-1m1jB:
undetectable
3h5gC-1m1jB:
undetectable
3h5gB-1m1jB:
5.29
3h5gC-1m1jB:
5.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 6 LEU C 124
LYS B 183
GLN B 185
GLU B 188
None
1.06A 3h5gB-1m1jC:
undetectable
3h5gC-1m1jC:
undetectable
3h5gB-1m1jC:
7.64
3h5gC-1m1jC:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 6 LYS C 120
LEU C 124
LYS B 183
GLU B 188
None
1.09A 3h5gB-1m1jC:
undetectable
3h5gC-1m1jC:
undetectable
3h5gB-1m1jC:
7.64
3h5gC-1m1jC:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_C_LEIC16_0
(COIL SER L16D-PEN)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus)
4 / 6 LYS C 120
LYS B 183
LEU B 187
GLU B 188
None
1.07A 3h5gB-1m1jC:
undetectable
3h5gC-1m1jC:
undetectable
3h5gB-1m1jC:
7.64
3h5gC-1m1jC:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_A_PNTA901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 ASP B 402
GLY B 438
SER B 450
VAL B 440
TYR B 421
None
1.32A 3hiiA-1m1jB:
0.0
3hiiA-1m1jB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HII_B_PNTB901_0
(AMILORIDE-SENSITIVE
AMINE OXIDASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 ASP B 402
GLY B 438
SER B 450
VAL B 440
TYR B 421
None
1.31A 3hiiB-1m1jB:
0.0
3hiiB-1m1jB:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 7 PHE B 267
GLY B 418
GLY B 263
PHE B 379
None
0.89A 3ko0M-1m1jB:
undetectable
3ko0P-1m1jB:
undetectable
3ko0M-1m1jB:
11.65
3ko0P-1m1jB:
11.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 7 PHE C 204
GLY C 346
GLY C 200
PHE C 312
None
0.86A 3ko0M-1m1jC:
undetectable
3ko0P-1m1jC:
undetectable
3ko0M-1m1jC:
12.47
3ko0P-1m1jC:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 8 HIS B 181
ASN C 117
MET C 116
ILE C 115
None
1.17A 3kp6A-1m1jB:
undetectable
3kp6B-1m1jB:
0.0
3kp6A-1m1jB:
14.79
3kp6B-1m1jB:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
3 / 3 LEU C 276
TRP C 334
GLY C 342
None
0.77A 3l35A-1m1jC:
4.5
3l35H-1m1jC:
undetectable
3l35A-1m1jC:
13.94
3l35H-1m1jC:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
3 / 3 LEU C 276
TRP C 334
GLY C 342
None
0.71A 3l35B-1m1jC:
4.4
3l35K-1m1jC:
undetectable
3l35B-1m1jC:
13.94
3l35K-1m1jC:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_B_SAMB401_0
(MNMC2)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 TYR B 274
GLY B 404
TYR B 382
ALA B 414
PHE B 379
None
1.22A 3vywB-1m1jB:
undetectable
3vywB-1m1jB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BCS_A_ACTA1126_0
(CHIMERIC AVIDIN)
1m1j FIBRINOGEN ALPHA
SUBUNIT

(Gallus
gallus)
4 / 4 THR A 129
GLN A 125
ARG A 126
THR A 122
None
1.32A 4bcsA-1m1jA:
undetectable
4bcsA-1m1jA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 8 ARG C 391
ASN C 189
ILE C 387
ASP C 152
None
1.05A 4d33A-1m1jC:
0.0
4d33A-1m1jC:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 7 SER B 347
ASN B 375
GLU B 359
ASN B 348
None
1.15A 4d33B-1m1jB:
0.0
4d33B-1m1jB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 7 ARG C 391
ASN C 189
ILE C 387
ASP C 152
None
1.05A 4d33B-1m1jC:
0.0
4d33B-1m1jC:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 7 SER B 347
ASN B 375
GLU B 359
ASN B 348
None
1.11A 4d39B-1m1jB:
0.0
4d39B-1m1jB:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 7 ARG C 391
ASN C 189
ILE C 387
ASP C 152
None
1.04A 4d39B-1m1jC:
undetectable
4d39B-1m1jC:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA502_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)
1m1j FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 8 TYR C  32
THR C  36
LEU C  40
VAL B  98
None
0.91A 4em2A-1m1jC:
undetectable
4em2A-1m1jC:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 8 ILE B 232
LYS B 313
ILE B 257
GLY B 252
None
0.93A 4hdlA-1m1jB:
undetectable
4hdlA-1m1jB:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ASP B 246
VAL B 243
TYR B 244
GLY B 253
SER B 227
None
1.18A 4mm5A-1m1jB:
undetectable
4mm5A-1m1jB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 11 TYR B 421
GLY B 263
SER B 450
GLY B 423
ASP A 154
None
1.29A 4mm9A-1m1jB:
undetectable
4mm9A-1m1jB:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 10 TYR B 421
GLY B 263
SER B 450
GLY B 423
ASP A 154
None
1.32A 4mmcA-1m1jB:
undetectable
4mmcA-1m1jB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ASP B 246
VAL B 243
TYR B 244
GLY B 253
SER B 227
None
1.23A 4mmeA-1m1jB:
undetectable
4mmeA-1m1jB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ASP B 246
VAL B 243
TYR B 244
GLY B 253
SER B 227
None
1.22A 4mmeB-1m1jB:
undetectable
4mmeB-1m1jB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ASP B 246
VAL B 243
TYR B 244
GLY B 253
SER B 227
None
1.29A 4mmfA-1m1jB:
undetectable
4mmfA-1m1jB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 9 ASP B 246
VAL B 243
TYR B 244
GLY B 253
SER B 227
None
1.23A 4mmfB-1m1jB:
undetectable
4mmfB-1m1jB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PB1_A_RBVA501_1
(NUPC FAMILY PROTEIN)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
5 / 12 GLY C 200
GLU C 225
ASN C 365
SER C 378
ILE C 367
None
1.27A 4pb1A-1m1jC:
undetectable
4pb1A-1m1jC:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUD_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 MET B 451
GLY B 446
TYR B 449
TYR B 421
SER B 362
None
1.37A 4xudA-1m1jB:
undetectable
4xudA-1m1jB:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_B_SAMB303_0
(CATECHOL
O-METHYLTRANSFERASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 MET B 451
GLY B 446
TYR B 449
TYR B 421
SER B 362
None
1.34A 4xueB-1m1jB:
undetectable
4xueB-1m1jB:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
3 / 3 TYR C 348
LYS C 381
LYS C 380
None
1.17A 5dbyA-1m1jC:
undetectable
5dbyA-1m1jC:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_A_K1SA304_0
(ADP-SUGAR
PYROPHOSPHATASE)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 5 GLU C 183
TRP C 191
VAL C 193
LEU C 246
None
1.47A 5qjqA-1m1jC:
0.0
5qjqB-1m1jC:
0.0
5qjqA-1m1jC:
19.83
5qjqB-1m1jC:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QJQ_B_K1SB304_0
(ADP-SUGAR
PYROPHOSPHATASE)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 5 TRP C 191
VAL C 193
LEU C 246
GLU C 183
None
1.47A 5qjqA-1m1jC:
0.0
5qjqB-1m1jC:
0.0
5qjqA-1m1jC:
19.83
5qjqB-1m1jC:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus;
Gallus
gallus)
4 / 8 ASN B 148
ILE C  90
LEU A 116
MET B 151
None
1.07A 5u4sB-1m1jB:
undetectable
5u4sB-1m1jB:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7F_A_SAMA301_1
(PUTATIVE
O-METHYLTRANSFERASE
RV1220C)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
4 / 4 SER B 380
ASP B 402
HIS B 412
ASP B 387
None
None
None
CA  B 503 (-3.0A)
1.48A 5x7fA-1m1jB:
undetectable
5x7fA-1m1jB:
15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
5 / 12 TYR B 426
GLY B 418
ASN B 417
ASN B 266
ASP B 437
None
1.36A 5yn6A-1m1jB:
undetectable
5yn6A-1m1jB:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_H_BEZH201_0
(NS3 PROTEASE)
1m1j FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus)
4 / 5 HIS C 343
SER C 332
TYR C 211
GLY C 333
None
1.40A 5yodH-1m1jC:
undetectable
5yodH-1m1jC:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)
1m1j FIBRINOGEN ALPHA
SUBUNIT
FIBRINOGEN BETA
CHAIN
FIBRINOGEN GAMMA
CHAIN

(Gallus
gallus;
Gallus
gallus;
Gallus
gallus)
4 / 5 ASN C  30
TYR A  63
VAL B  98
LEU B 102
None
1.24A 6a7pA-1m1jC:
undetectable
6a7pA-1m1jC:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
3 / 3 ARG B 384
LYS B 275
TYR B 342
None
1.07A 6gnaA-1m1jB:
undetectable
6gnaA-1m1jB:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)
1m1j FIBRINOGEN BETA
CHAIN

(Gallus
gallus)
3 / 3 ARG B 384
LYS B 275
TYR B 342
None
1.07A 6gnbA-1m1jB:
undetectable
6gnbA-1m1jB:
19.75