SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_A_SAMA200_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 11 ALA A 475
GLU A 471
LEU A 320
ALA A 452
LEU A 499
 None
 1.32A 1mjlA-1m22A:
undetectable
1mjlB-1m22A:
undetectable		 1mjlA-1m22A:
12.27
1mjlB-1m22A:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 7 PHE A 529
ARG A  74
ALA A 212
PRO A 527
 None
 1.11A 1oniA-1m22A:
undetectable
1oniB-1m22A:
undetectable		 1oniA-1m22A:
16.85
1oniB-1m22A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 7 PRO A 527
PHE A 529
ARG A  74
ALA A 212
 None
 1.03A 1oniG-1m22A:
undetectable
1oniI-1m22A:
undetectable		 1oniG-1m22A:
16.85
1oniI-1m22A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 7 ARG A 338
VAL A 451
ALA A 334
LEU A 337
 None
 0.86A 1pthA-1m22A:
undetectable		 1pthA-1m22A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 7 ARG A 338
VAL A 451
ALA A 334
LEU A 337
 None
 0.86A 1pthB-1m22A:
undetectable		 1pthB-1m22A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 6 LEU A 388
PHE A 391
ALA A 390
LEU A 408
 None
 1.00A 1ukbA-1m22A:
undetectable		 1ukbA-1m22A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 11 VAL A 160
ALA A 215
ILE A  75
ALA A  70
ASP A  79
 None
 1.26A 2admB-1m22A:
undetectable		 2admB-1m22A:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_1
(CATECHOL-O-METHYLTRA
NSFERASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 SER A  64
GLU A 105
ASP A 156
 None
 0.85A 2avdB-1m22A:
undetectable		 2avdB-1m22A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 ARG A 520
LEU A 308
LEU A 484
VAL A 268
 None
 0.86A 2bdmA-1m22A:
undetectable		 2bdmA-1m22A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 4 SER A 204
GLY A 201
HIS A 197
ASP A 492
 None
 1.26A 2oxtC-1m22A:
undetectable		 2oxtC-1m22A:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 ARG A 430
THR A 260
VAL A 243
 None
 0.95A 2q64A-1m22A:
undetectable		 2q64A-1m22A:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 ARG A 430
THR A 260
VAL A 243
 None
 1.00A 2qakA-1m22A:
0.0		 2qakA-1m22A:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 LEU A 371
LEU A 385
ALA A 380
ALA A 139
 None
 0.86A 2vcvF-1m22A:
undetectable		 2vcvF-1m22A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 LEU A 371
LEU A 385
ALA A 380
ALA A 139
 None
 0.81A 2vcvP-1m22A:
0.0		 2vcvP-1m22A:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 10 THR A 318
LEU A 329
VAL A 496
GLY A 497
GLY A 456
 None
 1.09A 2wd9C-1m22A:
undetectable		 2wd9C-1m22A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 ILE A 313
GLY A 314
ALA A 441
ALA A 452
VAL A 451
 None
 0.92A 3jb2A-1m22A:
0.0		 3jb2A-1m22A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		6 / 12 GLY A 205
GLY A 220
ALA A 218
ALA A 265
ALA A 271
ASP A 270
 None
 1.22A 3sudD-1m22A:
undetectable		 3sudD-1m22A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 6 PRO A 241
VAL A 274
THR A 221
THR A 260
 None
 0.99A 3tneA-1m22A:
undetectable		 3tneA-1m22A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7G_A_ACTA514_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 4 ALA A 265
VAL A 217
ASP A 270
LEU A 115
 None
 1.49A 4e7gA-1m22A:
0.2		 4e7gA-1m22A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J5J_B_478B401_2
(PROTEASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 10 ALA A 218
VAL A 274
GLY A 262
VAL A 236
VAL A 210
 None
 1.07A 4j5jB-1m22A:
undetectable		 4j5jB-1m22A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA407_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 GLU A 105
ARG A 112
HIS A 116
 None
 0.83A 4kf9A-1m22A:
0.0		 4kf9A-1m22A:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 ILE A 233
CYH A 229
GLY A 497
ILE A 491
ARG A 324
 None
 1.02A 4kicB-1m22A:
undetectable		 4kicB-1m22A:
24.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 PHE A 375
ILE A 252
ALA A 380
SER A 137
LEU A 385
 None
 1.37A 4qztC-1m22A:
0.0		 4qztC-1m22A:
11.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 ALA A 232
ALA A 452
LEU A 329
MET A 488
GLY A 489
 None
 1.21A 4r38A-1m22A:
undetectable		 4r38A-1m22A:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 4 ASN A 234
SER A 203
ALA A 207
VAL A 210
 None
 1.32A 4x1kC-1m22A:
undetectable		 4x1kC-1m22A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_B_SAMB301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 THR A 133
GLY A 163
ALA A 159
LEU A 115
ALA A 128
 None
 1.25A 5jglB-1m22A:
undetectable		 5jglB-1m22A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSA_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 12 VAL A 496
ILE A 461
SER A 196
HIS A 197
TRP A 459
 None
 1.50A 5lsaA-1m22A:
undetectable		 5lsaA-1m22A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 4 ASN A 234
SER A 203
ALA A 207
VAL A 210
 None
 1.39A 5nm5A-1m22A:
undetectable		 5nm5A-1m22A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 GLU A 222
GLY A 238
LEU A 239
THR A 485
 None
 1.07A 5sxqB-1m22A:
undetectable		 5sxqB-1m22A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_B_BEZB301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 SER A 255
ILE A 254
LEU A 363
LEU A 362
 None
 1.05A 5u4sB-1m22A:
undetectable		 5u4sB-1m22A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA405_0
(THIOREDOXIN
REDUCTASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 GLY A 113
LEU A 111
HIS A 116
 None
 0.63A 5u63A-1m22A:
undetectable		 5u63A-1m22A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		3 / 3 GLY A 113
LEU A 111
HIS A 116
 None
 0.63A 5u63B-1m22A:
undetectable		 5u63B-1m22A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 6 VAL A 208
ASN A 234
PRO A 230
ILE A 233
 None
 0.78A 6h7uA-1m22A:
undetectable		 6h7uA-1m22A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		4 / 8 VAL A 208
ASN A 234
PRO A 230
ILE A 233
 None
 0.74A 6hzpA-1m22A:
undetectable		 6hzpA-1m22A:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 1m22 PEPTIDE AMIDASE
(Stenotrophomonas
maltophilia) 		5 / 11 GLY A  82
LEU A  85
ALA A 212
ARG A  74
PHE A 529
 None
 1.44A 6qgbE-1m22A:
undetectable		 6qgbE-1m22A:
25.16