SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m2v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 SER B 316
PHE B 422
LEU B 309
LEU B 499
LEU B 512
 None
 1.40A 1e7wA-1m2vB:
2.4		 1e7wA-1m2vB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 PHE B 203
VAL B 600
ILE B 163
ASN B 176
LEU B 566
 None
 1.19A 1fm4A-1m2vB:
undetectable		 1fm4A-1m2vB:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_C_MK1C402_2
(HIV-II PROTEASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 8 ALA B 177
ILE B 628
PRO B 209
ILE B 207
ILE B 182
 None
 1.38A 1hshD-1m2vB:
undetectable		 1hshD-1m2vB:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 ARG B 672
ILE B 675
ALA B 659
PHE B 723
LEU B 668
 None
 1.22A 1og5B-1m2vB:
0.0		 1og5B-1m2vB:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC685_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.19A 1p7lC-1m2vB:
undetectable		 1p7lC-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7L_C_SAMC885_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.20A 1p7lD-1m2vB:
undetectable		 1p7lD-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_A_SAMA385_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.19A 1rg9A-1m2vB:
undetectable		 1rg9A-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_B_SAMB485_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.19A 1rg9B-1m2vB:
undetectable		 1rg9B-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC585_0
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.19A 1rg9C-1m2vB:
undetectable		 1rg9C-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG9_C_SAMC685_1
(S-ADENOSYLMETHIONINE
SYNTHETASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 HIS B 339
PRO B 337
THR B 556
ASP B 551
 None
 1.19A 1rg9D-1m2vB:
undetectable		 1rg9D-1m2vB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 PHE B 540
SER B 541
ILE B 336
THR B 325
 None
 0.90A 1sbrA-1m2vB:
0.0		 1sbrA-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 7 PHE B 540
ILE B 336
ILE B 548
THR B 325
 None
 0.92A 1sbrB-1m2vB:
undetectable		 1sbrB-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 7 PHE B 540
SER B 541
ILE B 336
THR B 325
 None
 0.84A 1sbrB-1m2vB:
undetectable		 1sbrB-1m2vB:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 11 SER B 446
ALA B 323
LEU B 321
ILE B 537
PHE B 544
 None
 1.13A 1uduA-1m2vB:
0.8		 1uduA-1m2vB:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_B_H4BB1290_1
(PTERIDINE REDUCTASE
1)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 8 SER B 316
PHE B 422
LEU B 309
LEU B 499
LEU B 512
 None
 1.33A 2bfpB-1m2vB:
2.3		 2bfpB-1m2vB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 8 SER B 316
PHE B 422
LEU B 309
LEU B 499
LEU B 512
 None
 1.41A 2bfpC-1m2vB:
2.7		 2bfpC-1m2vB:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 9 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 1.02A 2f78A-1m2vB:
undetectable		 2f78A-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 9 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 0.98A 2f78B-1m2vB:
2.3		 2f78B-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 9 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 1.03A 2f7aA-1m2vB:
undetectable		 2f7aA-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 9 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 1.00A 2f7aB-1m2vB:
2.4		 2f7aB-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 10 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 1.02A 2f8dA-1m2vB:
2.2		 2f8dA-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 10 LEU B 330
LEU B 329
ILE B 326
LEU B 406
ILE B 403
 None
 1.03A 2f8dB-1m2vB:
2.4		 2f8dB-1m2vB:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 406
THR B 405
LEU B 333
LEU B 330
ILE B 345
 None
 0.95A 2ouzA-1m2vB:
undetectable		 2ouzA-1m2vB:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 ASN B 239
VAL B 242
TYR B 290
ASN B 260
 None
 1.11A 2wekA-1m2vB:
undetectable		 2wekA-1m2vB:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_B_DIFB1373_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 ASN B 239
VAL B 242
TYR B 290
ASN B 260
 None
 1.08A 2wekB-1m2vB:
2.1		 2wekB-1m2vB:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 PHE B 241
ASN B 239
PHE B 255
 None
 0.90A 2zbuD-1m2vB:
2.8		 2zbuD-1m2vB:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 872
GLU B 543
ASP B 591
 None
 0.83A 3bxoA-1m2vB:
undetectable		 3bxoA-1m2vB:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 7 TYR B 483
GLY B 455
VAL B 350
LEU B 515
 None
 0.69A 3elzA-1m2vB:
0.0		 3elzA-1m2vB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 ILE B 442
ILE B 495
VAL B 493
GLY B 437
LEU B 386
 None
 1.01A 3em0B-1m2vB:
0.0		 3em0B-1m2vB:
9.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_B_TOPB200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 ALA B 650
LEU B 745
ILE B 752
LEU B 717
THR B 185
 None
 1.10A 3fl9B-1m2vB:
undetectable		 3fl9B-1m2vB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 10 ALA B 650
LEU B 745
ILE B 752
LEU B 717
THR B 185
 None
 0.96A 3fl9E-1m2vB:
undetectable		 3fl9E-1m2vB:
11.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 5 THR B 867
THR B 523
HIS B 574
HIS B 547
 None
 1.37A 3g1uC-1m2vB:
undetectable		 3g1uC-1m2vB:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 ALA B 722
PHE B 723
LEU B 476
ALA B 671
 None
 0.85A 3hrdA-1m2vB:
0.0
3hrdB-1m2vB:
0.0		 3hrdA-1m2vB:
18.00
3hrdB-1m2vB:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 11 SER B 315
LEU B 499
SER B 446
PHE B 500
ASP B 731
 None
 1.46A 3ko0A-1m2vB:
undetectable
3ko0B-1m2vB:
1.3
3ko0C-1m2vB:
1.2
3ko0D-1m2vB:
1.4		 3ko0A-1m2vB:
7.34
3ko0B-1m2vB:
7.34
3ko0C-1m2vB:
7.34
3ko0D-1m2vB:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 11 ASP B 731
LEU B 499
SER B 446
PHE B 500
SER B 315
 None
 1.48A 3ko0E-1m2vB:
0.0
3ko0F-1m2vB:
undetectable
3ko0G-1m2vB:
0.0
3ko0H-1m2vB:
undetectable		 3ko0E-1m2vB:
7.34
3ko0F-1m2vB:
7.34
3ko0G-1m2vB:
7.34
3ko0H-1m2vB:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 ASP B 731
LEU B 499
SER B 446
PHE B 500
SER B 315
 None
 1.47A 3ko0G-1m2vB:
0.0
3ko0H-1m2vB:
undetectable
3ko0I-1m2vB:
1.3
3ko0J-1m2vB:
0.0		 3ko0G-1m2vB:
7.34
3ko0H-1m2vB:
7.34
3ko0I-1m2vB:
7.34
3ko0J-1m2vB:
7.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 8 ASP B 480
LEU B 512
LEU B 457
SER B 477
 None
 0.95A 3lm8A-1m2vB:
3.1
3lm8C-1m2vB:
undetectable		 3lm8A-1m2vB:
13.42
3lm8C-1m2vB:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 11 GLU B 404
ILE B 548
ALA B 545
ASP B 334
GLN B 331
 None
 1.08A 3nmuB-1m2vB:
1.6
3nmuJ-1m2vB:
undetectable		 3nmuB-1m2vB:
17.55
3nmuJ-1m2vB:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 4 PRO B 711
LEU B 143
ILE B 141
ARG B 702
 None
 1.27A 3w1wA-1m2vB:
3.5		 3w1wA-1m2vB:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ASD_A_BAXA1500_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 6 ILE B 435
VAL B 497
LEU B 499
ILE B 443
 None
 0.91A 4asdA-1m2vB:
undetectable		 4asdA-1m2vB:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 ARG B 252
ARG B 257
ILE B 245
 None
 0.90A 4b7qC-1m2vB:
undetectable		 4b7qC-1m2vB:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 4 LEU B 424
ILE B 442
GLY B 425
PHE B 486
 None
 0.91A 4dc3A-1m2vB:
undetectable		 4dc3A-1m2vB:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 LEU B 649
ALA B 650
LEU B 205
ILE B 207
LEU B 161
 None
 1.03A 4dm8B-1m2vB:
undetectable		 4dm8B-1m2vB:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 237
ARG B 561
SER B 236
 None
 1.10A 4dr2I-1m2vB:
0.0
4dr2J-1m2vB:
undetectable		 4dr2I-1m2vB:
8.86
4dr2J-1m2vB:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 THR B 893
LEU B 896
ALA B 898
SER B 900
MET B 721
 None
 1.38A 4ejwA-1m2vB:
0.0		 4ejwA-1m2vB:
10.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KTV_A_ADNA403_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 LYS B 546
SER B 549
ASP B 864
ASP B 215
ILE B 217
 None
 1.09A 4ktvA-1m2vB:
0.0
4ktvB-1m2vB:
0.0		 4ktvA-1m2vB:
17.30
4ktvB-1m2vB:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 237
ARG B 561
SER B 236
 None
 1.03A 4lf7I-1m2vB:
0.0
4lf7J-1m2vB:
0.0		 4lf7I-1m2vB:
8.86
4lf7J-1m2vB:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 594
ARG B 208
SER B 593
 None
 1.17A 4lf7I-1m2vB:
0.0
4lf7J-1m2vB:
0.0		 4lf7I-1m2vB:
8.86
4lf7J-1m2vB:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 237
ARG B 561
SER B 236
 None
 1.03A 4lf8I-1m2vB:
0.0
4lf8J-1m2vB:
0.0		 4lf8I-1m2vB:
8.86
4lf8J-1m2vB:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 TYR B 594
ARG B 208
SER B 593
 None
 1.17A 4lf8I-1m2vB:
0.0
4lf8J-1m2vB:
0.0		 4lf8I-1m2vB:
8.86
4lf8J-1m2vB:
6.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 ASP B 536
TRP B 897
SER B 870
 None
 1.04A 4lrhB-1m2vB:
0.0		 4lrhB-1m2vB:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 ASP B 536
TRP B 897
SER B 870
 None
 1.02A 4lrhF-1m2vB:
0.0		 4lrhF-1m2vB:
13.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 LEU B 156
ASP B 647
ILE B 151
 None
 0.63A 4xi3D-1m2vB:
undetectable		 4xi3D-1m2vB:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 4 ILE B 228
ARG B 280
TYR B 290
GLU B 282
 None
 1.14A 4zzbD-1m2vB:
4.6		 4zzbD-1m2vB:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 5 ILE B 228
ARG B 280
TYR B 290
GLU B 282
 None
 1.12A 4zzcE-1m2vB:
4.5		 4zzcE-1m2vB:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 ARG B 517
ASN B 738
ASP B 731
 None
 0.90A 5gwxA-1m2vB:
undetectable		 5gwxA-1m2vB:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OJ0_A_9WTA801_0
(PENICILLIN-BINDING
PROTEIN 2X)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		5 / 12 ASN B 417
SER B 319
SER B 503
GLY B 447
THR B 448
 None
 1.31A 5oj0A-1m2vB:
undetectable		 5oj0A-1m2vB:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 7 ARG B 570
TYR B 572
GLU B 597
LEU B 674
 None
 1.08A 5umwB-1m2vB:
0.0
5umwE-1m2vB:
0.0		 5umwB-1m2vB:
6.92
5umwE-1m2vB:
6.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		3 / 3 ILE B 787
VAL B 756
PRO B 754
 None
 0.70A 5uunA-1m2vB:
undetectable		 5uunA-1m2vB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1m2v PROTEIN TRANSPORT
PROTEIN SEC24
(Saccharomyces
cerevisiae) 		4 / 7 HIS B 524
HIS B 862
GLU B 543
GLU B 807
 None
 1.33A 6mn4F-1m2vB:
0.0		 6mn4F-1m2vB:
14.86