SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ME7_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 ASP A 167
ILE A 175
GLY A 174
CYH A 194
 PLP  A4401 (-2.9A)
None
None
None
 0.54A 1me7A-1m32A:
undetectable		 1me7A-1m32A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S3Z_B_RIOB501_0
(AMINOGLYCOSIDE
6'-N-ACETYLTRANSFERA
SE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 VAL A  69
ARG A 339
GLU A 141
ASP A 167
 None
POA  A4601 (-3.4A)
None
PLP  A4401 (-2.9A)
 1.30A 1s3zA-1m32A:
undetectable
1s3zB-1m32A:
undetectable		 1s3zA-1m32A:
18.13
1s3zB-1m32A:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 PHE A 251
GLN A  45
SER A 189
LEU A  49
TYR A 271
 None
 1.34A 1u72A-1m32A:
2.1		 1u72A-1m32A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_A_GBNA502_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 TYR A  56
THR A  51
ALA A  50
VAL A 166
 None
 0.81A 2a1hA-1m32A:
undetectable
2a1hB-1m32A:
undetectable		 2a1hA-1m32A:
23.09
2a1hB-1m32A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 8 VAL A 166
TYR A  56
THR A  51
ALA A  50
 None
 0.84A 2a1hA-1m32A:
undetectable
2a1hB-1m32A:
undetectable		 2a1hA-1m32A:
23.09
2a1hB-1m32A:
23.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 LEU A  60
LEU A  46
LEU A 255
ALA A 254
ALA A 191
 None
 1.22A 2bxpA-1m32A:
undetectable		 2bxpA-1m32A:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 10 TYR A 109
ALA A 121
ILE A 135
PRO A 130
ILE A 132
 None
 1.30A 2dm6A-1m32A:
5.0
2dm6B-1m32A:
5.2		 2dm6A-1m32A:
24.32
2dm6B-1m32A:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACTB601_0
(ACETYLCHOLINESTERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		4 / 7 GLY A 263
GLY A 262
ALA A 265
ALA A 266
 None
 0.67A 2ha4B-1m32A:
undetectable		 2ha4B-1m32A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 TYR A  91
THR A 142
ASP A 167
SER A 170
LYS A 193
 PLP  A4401 ( 3.6A)
PLP  A4401 (-3.2A)
PLP  A4401 (-2.9A)
PLP  A4401 ( 3.8A)
PLP  A4401 ( 4.2A)
 0.70A 2z9wA-1m32A:
42.5		 2z9wA-1m32A:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_A_PXLA1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 TYR A  91
THR A 142
SER A 170
ASN A 192
LYS A 193
 PLP  A4401 ( 3.6A)
PLP  A4401 (-3.2A)
PLP  A4401 ( 3.8A)
None
PLP  A4401 ( 4.2A)
 0.82A 2z9wA-1m32A:
42.5		 2z9wA-1m32A:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 TYR A  91
THR A 142
ASP A 167
SER A 170
LYS A 193
 PLP  A4401 ( 3.6A)
PLP  A4401 (-3.2A)
PLP  A4401 (-2.9A)
PLP  A4401 ( 3.8A)
PLP  A4401 ( 4.2A)
 0.70A 2z9wB-1m32A:
42.4		 2z9wB-1m32A:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z9W_B_PXLB1197_1
(ASPARTATE
AMINOTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 TYR A  91
THR A 142
SER A 170
ASN A 192
LYS A 193
 PLP  A4401 ( 3.6A)
PLP  A4401 (-3.2A)
PLP  A4401 ( 3.8A)
None
PLP  A4401 ( 4.2A)
 0.84A 2z9wB-1m32A:
42.4		 2z9wB-1m32A:
27.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEC_A_STIA1_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 VAL A  59
ALA A 206
ILE A 165
LEU A 211
ASP A 167
 None
None
None
None
PLP  A4401 (-2.9A)
 0.95A 3hecA-1m32A:
undetectable		 3hecA-1m32A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A  65
GLY A  63
MET A 169
GLU A  70
ALA A  68
 PLP  A4401 (-3.6A)
None
PLP  A4401 (-4.6A)
None
None
 1.25A 3t7sA-1m32A:
3.5		 3t7sA-1m32A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A  65
GLY A  63
MET A 169
GLU A  70
ALA A  68
 PLP  A4401 (-3.6A)
None
PLP  A4401 (-4.6A)
None
None
 1.21A 3t7sB-1m32A:
2.6		 3t7sB-1m32A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_C_SAMC300_0
(PUTATIVE
METHYLTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A  65
GLY A  63
MET A 169
GLU A  70
ALA A  68
 PLP  A4401 (-3.6A)
None
PLP  A4401 (-4.6A)
None
None
 1.25A 3t7sC-1m32A:
3.6		 3t7sC-1m32A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A  65
GLY A  63
MET A 169
GLU A  70
ALA A  68
 PLP  A4401 (-3.6A)
None
PLP  A4401 (-4.6A)
None
None
 1.24A 3t7sD-1m32A:
3.7		 3t7sD-1m32A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 12 ALA A 280
SER A 277
PHE A 338
ILE A 340
PHE A 303
 None
 1.19A 4c49A-1m32A:
0.0		 4c49A-1m32A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 11 GLY A 200
ALA A 252
ILE A  42
LEU A  46
MET A 169
 None
None
None
None
PLP  A4401 (-4.6A)
 1.18A 4xumB-1m32A:
0.0		 4xumB-1m32A:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		3 / 3 GLU A  40
TRP A 229
ASN A 235
 None
 1.13A 5dv4A-1m32A:
0.0		 5dv4A-1m32A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 1m32 2-AMINOETHYLPHOSPHON
ATE-PYRUVATE
AMINOTRANSFERASE
(Salmonella
enterica) 		5 / 9 ILE A 104
ALA A  99
GLY A 100
LEU A 101
GLY A  92
 None
 1.19A 6nm4B-1m32A:
0.0		 6nm4B-1m32A:
21.11