SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m33'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.89A 1v55P-1m33A:
undetectable
1v55W-1m33A:
undetectable		 1v55P-1m33A:
20.57
1v55W-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 183
GLY A  23
GLY A  21
LEU A  19
GLY A  80
 3OH  A 300 (-4.3A)
None
3OH  A 300 (-3.6A)
None
None
 1.08A 1y4lA-1m33A:
undetectable		 1y4lA-1m33A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ADM_B_SAMB500_0
(ADENINE-N6-DNA-METHY
LTRANSFERASE TAQI)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		6 / 11 VAL A  87
GLU A  66
ALA A  67
ALA A  72
PRO A  48
PHE A  56
 None
 1.36A 2admB-1m33A:
undetectable		 2admB-1m33A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.84A 2dysC-1m33A:
undetectable
2dysJ-1m33A:
undetectable		 2dysC-1m33A:
20.57
2dysJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.88A 2eijP-1m33A:
undetectable
2eijW-1m33A:
undetectable		 2eijP-1m33A:
20.57
2eijW-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 8 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.85A 2eilP-1m33A:
undetectable
2eilW-1m33A:
undetectable		 2eilP-1m33A:
20.57
2eilW-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_2
(ADENOSINE DEAMINASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 LEU A 249
LEU A  44
PHE A 245
 None
 0.70A 2pgrA-1m33A:
2.5		 2pgrA-1m33A:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 180
LEU A 183
HIS A 235
PRO A 211
VAL A 214
 None
3OH  A 300 (-4.3A)
3OH  A 300 (-4.3A)
None
None
 1.09A 2pnjA-1m33A:
2.9		 2pnjA-1m33A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.85A 2zxwC-1m33A:
undetectable
2zxwJ-1m33A:
undetectable		 2zxwC-1m33A:
20.57
2zxwJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 6 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.89A 2zxwP-1m33A:
undetectable
2zxwW-1m33A:
undetectable		 2zxwP-1m33A:
20.57
2zxwW-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 6 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.85A 3ag1C-1m33A:
undetectable
3ag1J-1m33A:
0.0		 3ag1C-1m33A:
20.57
3ag1J-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 8 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.91A 3asoC-1m33A:
undetectable
3asoJ-1m33A:
undetectable		 3asoC-1m33A:
20.57
3asoJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 LEU A  42
GLU A  35
ILE A  32
 None
 0.59A 3czhA-1m33A:
0.0		 3czhA-1m33A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 8 GLY A 178
ALA A  58
ASP A 174
GLY A  49
LEU A  47
 None
 1.31A 3em6A-1m33A:
undetectable		 3em6A-1m33A:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 5 ARG A 189
LEU A 218
PRO A 211
VAL A 214
 None
 1.11A 3ufnA-1m33A:
0.0
3ufnB-1m33A:
0.0		 3ufnA-1m33A:
15.97
3ufnB-1m33A:
15.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 6 GLY A 204
TYR A 228
ALA A 106
TYR A 203
 None
 0.95A 4ae1A-1m33A:
undetectable		 4ae1A-1m33A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 10 ALA A  65
VAL A  68
MET A  64
SER A  53
VAL A  45
 None
 1.22A 4da7A-1m33A:
undetectable		 4da7A-1m33A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_A_NCTA501_1
(CYTOCHROME P450 2A13)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 PHE A 238
PHE A 245
ALA A 106
LEU A  79
 None
 0.99A 4ejgA-1m33A:
0.0		 4ejgA-1m33A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 SER A  60
ALA A  58
VAL A 175
 None
 0.60A 4o2bA-1m33A:
3.4		 4o2bA-1m33A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 SER A  60
ALA A  58
VAL A 175
 None
 0.66A 4o2bC-1m33A:
3.2		 4o2bC-1m33A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.92A 5b1aC-1m33A:
undetectable
5b1aJ-1m33A:
undetectable		 5b1aC-1m33A:
20.57
5b1aJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.94A 5b1aP-1m33A:
undetectable
5b1aW-1m33A:
undetectable		 5b1aP-1m33A:
20.57
5b1aW-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.91A 5b3sC-1m33A:
undetectable
5b3sJ-1m33A:
0.0		 5b3sC-1m33A:
20.57
5b3sJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.93A 5b3sP-1m33A:
undetectable		 5b3sP-1m33A:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 4 ALA A 167
PRO A 171
LEU A  83
HIS A  20
 None
None
3OH  A 300 (-4.2A)
None
 1.47A 5eskA-1m33A:
0.0		 5eskA-1m33A:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.92A 5iy5C-1m33A:
undetectable
5iy5J-1m33A:
undetectable		 5iy5C-1m33A:
20.21
5iy5J-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA607_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.83A 5jsdA-1m33A:
0.0		 5jsdA-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.83A 5jsdB-1m33A:
0.1		 5jsdB-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_C_1GNC608_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.83A 5jsdC-1m33A:
0.9		 5jsdC-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.83A 5jseA-1m33A:
0.0		 5jseA-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.83A 5jseB-1m33A:
0.0		 5jseB-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 THR A 104
SER A 107
TYR A 203
 None
 0.84A 5jseC-1m33A:
0.0		 5jseC-1m33A:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 GLY A  21
GLY A 119
VAL A 210
ILE A 120
GLY A 179
 3OH  A 300 (-3.6A)
None
None
None
None
 0.95A 5koxA-1m33A:
undetectable		 5koxA-1m33A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		3 / 3 VAL A  99
ARG A 189
PRO A 191
 None
 0.62A 5koxA-1m33A:
undetectable		 5koxA-1m33A:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 183
LEU A 180
GLY A 179
GLY A 178
VAL A 175
 3OH  A 300 (-4.3A)
None
None
None
None
 0.76A 5uc1A-1m33A:
undetectable		 5uc1A-1m33A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 LEU A 183
LEU A 180
GLY A 179
GLY A 178
VAL A 175
 3OH  A 300 (-4.3A)
None
None
None
None
 0.77A 5uc1B-1m33A:
undetectable		 5uc1B-1m33A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		5 / 12 SER A  53
LEU A  19
ILE A   4
ALA A  67
ALA A  58
 None
 1.12A 5vc0A-1m33A:
0.0		 5vc0A-1m33A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.91A 5z84C-1m33A:
undetectable
5z84J-1m33A:
undetectable		 5z84C-1m33A:
20.57
5z84J-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 7 LEU A 132
GLN A 131
PHE A 128
LEU A 176
 None
 0.90A 5zcqC-1m33A:
undetectable
5zcqJ-1m33A:
undetectable		 5zcqC-1m33A:
20.57
5zcqJ-1m33A:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1m33 BIOH PROTEIN
(Escherichia
coli) 		4 / 5 PRO A 237
VAL A 105
GLY A  23
VAL A  28
 None
 0.98A 6ak3B-1m33A:
0.0		 6ak3B-1m33A:
14.96