SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m3a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 1m3a PROTO-ONCOGENE C-CRK
(Mus
musculus) 		3 / 3 PRO A 152
LEU A 151
ARG A 179
 None
 0.85A 3aqiA-1m3aA:
undetectable		 3aqiA-1m3aA:
11.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 1m3a PROTO-ONCOGENE C-CRK
(Mus
musculus) 		5 / 12 LEU A 151
ILE A 161
VAL A 184
VAL A 187
VAL A 137
 None
 1.17A 5dpdB-1m3aA:
undetectable		 5dpdB-1m3aA:
7.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 1m3a PROTO-ONCOGENE C-CRK
(Mus
musculus) 		5 / 12 LEU A 159
PRO A 183
VAL A 184
TRP A 169
PHE A 153
 None
 1.33A 5jo9A-1m3aA:
undetectable		 5jo9A-1m3aA:
12.92