SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m3d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		3 / 3 TRP C  81
ARG C  75
THR C  58
 None
 0.97A 1df7A-1m3dC:
undetectable		 1df7A-1m3dC:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		4 / 6 ASP C  45
SER C  51
ASN C  43
SER C 160
 None
 1.35A 1kiaC-1m3dC:
undetectable		 1kiaC-1m3dC:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		4 / 8 GLY C 152
ASN C  43
PHE C 170
TYR C  34
 None
 1.39A 3ccfA-1m3dC:
undetectable		 3ccfA-1m3dC:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		4 / 7 LEU C  48
ASP C  45
SER C 157
HIS C  10
 None
 1.18A 4arcA-1m3dC:
undetectable		 4arcA-1m3dC:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		4 / 7 LEU C  48
ASP C  45
SER C 157
TYR C   5
 None
 1.30A 4arcA-1m3dC:
undetectable		 4arcA-1m3dC:
13.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		3 / 3 HIS C 181
GLU C 172
ASN C 185
 None
 1.00A 4bupB-1m3dC:
0.0		 4bupB-1m3dC:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTW_A_DB8A1101_2
(RECEPTOR
TYROSINE-PROTEIN
KINASE ERBB-3)		 1m3d TYPE IV COLLAGEN
NONCOLLAGENOUS
DOMAIN- ALPHA2
(Bos
taurus) 		3 / 3 LEU C 141
LEU C  82
ASN C  43
 None
 0.75A 4otwA-1m3dC:
undetectable		 4otwA-1m3dC:
18.98