SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m3s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		3 / 3 GLU A  13
ILE A  10
ARG A  46
 None
 0.57A 1cd2A-1m3sA:
undetectable		 1cd2A-1m3sA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 11 ILE A  84
ALA A  51
PHE A  54
LEU A  58
ILE A  67
 None
 1.10A 1uduA-1m3sA:
undetectable		 1uduA-1m3sA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		3 / 3 GLY A  87
GLY A  89
THR A  91
 None
 0.26A 3si7B-1m3sA:
undetectable		 3si7B-1m3sA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 11 ILE A  39
GLU A  70
GLY A  85
LYS A  52
TYR A 159
 None
 1.42A 4j83A-1m3sA:
undetectable		 4j83A-1m3sA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 12 ILE A  21
PHE A 158
ILE A  83
LEU A  29
ILE A 127
 None
 1.02A 4kjjA-1m3sA:
undetectable		 4kjjA-1m3sA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 12 ILE A  21
PHE A 158
ILE A  83
LEU A  29
ILE A 127
 None
 1.07A 4kjkA-1m3sA:
undetectable		 4kjkA-1m3sA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NQA_H_9CRH501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 12 ILE A  39
ALA A  55
ILE A 107
HIS A  32
LEU A  29
 None
 0.81A 4nqaH-1m3sA:
undetectable		 4nqaH-1m3sA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 12 ILE A  21
PHE A 158
ILE A  83
LEU A  29
ILE A 127
 None
 1.01A 4p3qA-1m3sA:
undetectable		 4p3qA-1m3sA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		4 / 8 GLY A 106
ALA A 101
GLY A  79
SER A  36
 None
 0.66A 5vw9A-1m3sA:
undetectable		 5vw9A-1m3sA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1m3s HYPOTHETICAL PROTEIN
YCKF
(Bacillus
subtilis) 		5 / 12 ILE A  39
ALA A  55
ILE A 107
HIS A  32
LEU A  29
 None
 1.01A 6a60D-1m3sA:
undetectable		 6a60D-1m3sA:
20.93