SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m3v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		3 / 3 ARG A  59
THR A  91
VAL A  86
 None
 0.97A 1hxbA-1m3vA:
undetectable		 1hxbA-1m3vA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_D_ADND1504_1
(CLASS B ACID
PHOSPHATASE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		4 / 8 ASP A  61
ASP A  83
THR A  51
TYR A  50
 ZN  A 124 (-2.7A)
None
None
None
 0.99A 1rmtD-1m3vA:
undetectable		 1rmtD-1m3vA:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		3 / 3 ARG A  59
SER A  80
TYR A  50
 None
 1.01A 2q2hA-1m3vA:
0.0
2q2hB-1m3vA:
0.0		 2q2hA-1m3vA:
21.09
2q2hB-1m3vA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_2
(PROTEASE RETROPEPSIN)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		3 / 3 ARG A  59
THR A  91
VAL A  86
 None
 0.87A 2q64A-1m3vA:
undetectable		 2q64A-1m3vA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		3 / 3 ARG A  59
THR A  91
VAL A  86
 None
 0.91A 2qakA-1m3vA:
undetectable		 2qakA-1m3vA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		5 / 11 GLY A  81
GLU A 100
SER A  48
ASP A  83
VAL A  87
 None
 0.92A 4d9hA-1m3vA:
undetectable		 4d9hA-1m3vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		5 / 11 GLY A  81
GLU A 100
SER A  48
ASP A  83
VAL A  87
 None
 0.92A 4danA-1m3vA:
undetectable		 4danA-1m3vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		5 / 12 GLY A  81
GLU A 100
SER A  48
ASP A  83
VAL A  87
 None
 0.96A 4danA-1m3vA:
undetectable
4danB-1m3vA:
undetectable		 4danA-1m3vA:
18.36
4danB-1m3vA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		4 / 7 ARG A 103
ASP A  83
GLY A  98
GLU A  96
 None
 0.95A 5btaA-1m3vA:
undetectable
5btaC-1m3vA:
undetectable
5btaD-1m3vA:
undetectable		 5btaA-1m3vA:
14.05
5btaC-1m3vA:
14.05
5btaD-1m3vA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		4 / 7 ASP A  83
GLY A  98
GLU A  96
ARG A 103
 None
 0.94A 5btfA-1m3vA:
undetectable
5btfB-1m3vA:
undetectable
5btfC-1m3vA:
undetectable		 5btfA-1m3vA:
14.05
5btfB-1m3vA:
20.70
5btfC-1m3vA:
14.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1m3v FUSION OF THE LIM
INTERACTING DOMAIN
OF LDB1 AND THE
N-TERMINAL LIM
DOMAIN OF LMO4
(Mus
musculus) 		4 / 7 ARG A 103
ASP A  83
GLY A  98
GLU A  96
 None
 0.87A 5btgA-1m3vA:
undetectable
5btgC-1m3vA:
undetectable
5btgD-1m3vA:
undetectable		 5btgA-1m3vA:
13.84
5btgC-1m3vA:
13.84
5btgD-1m3vA:
20.70