SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m41'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		3 / 3 TRP A 196
ARG A 314
THR A 195
 None
 0.99A 1df7A-1m41A:
undetectable		 1df7A-1m41A:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		4 / 7 THR A  82
ALA A  92
PHE A 104
LEU A 161
 None
 1.15A 2hzqA-1m41A:
undetectable		 2hzqA-1m41A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		3 / 3 LEU A 334
TYR A 338
GLY A 341
 None
 0.61A 2ocuA-1m41A:
undetectable		 2ocuA-1m41A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		4 / 5 ASN A 105
ALA A  61
LEU A  71
GLY A  45
 None
 0.96A 3dl9A-1m41A:
0.0		 3dl9A-1m41A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O14_A_NIOA300_1
(ANTI-ECFSIGMA
FACTOR, CHRR)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		4 / 7 ARG A 127
SER A  80
VAL A 120
VAL A  81
 None
 0.83A 3o14A-1m41A:
undetectable		 3o14A-1m41A:
24.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		5 / 8 ASP A 236
ASN A 235
ALA A 238
VAL A 305
GLU A 243
 None
 1.47A 4zbqA-1m41A:
0.0		 4zbqA-1m41A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		5 / 12 LEU A 106
PHE A 175
GLU A 188
VAL A 190
GLY A 151
 None
 1.20A 5f9zB-1m41A:
undetectable		 5f9zB-1m41A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		5 / 12 TYR A 128
SER A 179
VAL A 181
TYR A 193
PHE A 175
 None
 1.18A 5g6sB-1m41A:
undetectable
5g6sC-1m41A:
undetectable		 5g6sB-1m41A:
23.54
5g6sC-1m41A:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		4 / 4 LEU A 227
MET A   4
ILE A 230
LEU A 344
 None
 1.06A 5nfpA-1m41A:
undetectable		 5nfpA-1m41A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 1m41 FMNH2-DEPENDENT
ALKANESULFONATE
MONOOXYGENASE
(Escherichia
coli) 		4 / 6 ARG A 101
SER A  98
ALA A  62
ALA A  35
 None
 1.16A 6ma6A-1m41A:
0.0		 6ma6A-1m41A:
11.14