SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m46'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 1m46 IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN
MYOSIN LIGHT CHAIN
(Saccharomyces
cerevisiae) 		4 / 8 ILE B 866
LEU A 126
PHE A 142
PHE A  90
 None
 0.90A 2vctB-1m46B:
undetectable		 2vctB-1m46B:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 1m46 MYOSIN LIGHT CHAIN
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  31
GLY A  35
LEU A  27
SER A  26
 None
 0.93A 3aiaA-1m46A:
undetectable		 3aiaA-1m46A:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WSJ_A_MK1A201_2
(PROTEASE)		 1m46 IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN
MYOSIN LIGHT CHAIN
(Saccharomyces
cerevisiae) 		4 / 7 LEU B 856
ALA A  89
VAL A 101
ILE B 859
 None
 0.92A 3wsjB-1m46B:
undetectable		 3wsjB-1m46B:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M51_A_BEZA501_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1m46 MYOSIN LIGHT CHAIN
IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 ILE B 859
ILE B 866
PHE A  90
LEU A 106
 None
 0.87A 4m51A-1m46B:
undetectable		 4m51A-1m46B:
6.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 1m46 MYOSIN LIGHT CHAIN
IQ4 MOTIF FROM
MYO2P, A CLASS V
MYOSIN
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 8 ILE A 143
PHE A  86
VAL A 146
GLN B 863
 None
 0.99A 5dqyA-1m46A:
undetectable		 5dqyA-1m46A:
24.83