SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m4v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WEK_A_DIFA1375_1 (ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2)	1m4v	SET3, SUPERANTIGEN-LIKE PROTEIN (Staphylococcus aureus)	3 / 3	LEU A 148 TYR A 147 GLN A 150	None	0.68A	2wekA-1m4vA: undetectable	2wekA-1m4vA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MWS_B_017B201_2 (HIV-1 PROTEASE)	1m4v	SET3, SUPERANTIGEN-LIKE PROTEIN (Staphylococcus aureus)	5 / 12	LEU A 28 VAL A 94 ILE A 57 VAL A 77 ILE A 75	None	1.16A	3mwsB-1m4vA: undetectable	3mwsB-1m4vA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KQY_B_017B101_1 (PROTEASE E35D-DRV)	1m4v	SET3, SUPERANTIGEN-LIKE PROTEIN (Staphylococcus aureus)	5 / 12	LEU A 28 VAL A 94 ILE A 57 VAL A 77 ILE A 75	None	1.13A	5kqyA-1m4vA: undetectable	5kqyA-1m4vA: 22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGC_A_ACTA811_0 (GEPHYRIN)	1m4v	SET3, SUPERANTIGEN-LIKE PROTEIN (Staphylococcus aureus)	3 / 3	LEU A 148 LEU A 178 ARG A 145	None	0.62A	6fgcA-1m4vA: undetectable	6fgcA-1m4vA: 18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA810_0 (GEPHYRIN)	1m4v	SET3, SUPERANTIGEN-LIKE PROTEIN (Staphylococcus aureus)	3 / 3	LEU A 148 LEU A 178 ARG A 145	None	0.62A	6fgdA-1m4vA: undetectable	6fgdA-1m4vA: 18.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2WEK_A_DIFA1375_1","ZINC-BINDING ALCOHOL DEHYDROGENASE DOMAIN-CONTAINING PROTEIN 2","1m4v","SET3, SUPERANTIGEN-LIKE PROTEIN","Staphylococcus aureus",3,"LEU A 148;TYR A 147;GLN A 150","None","0.68A","2wekA-1m4vA:undetectable","2wekA-1m4vA:20.94"],["3MWS_B_017B201_2","HIV-1 PROTEASE","1m4v","SET3, SUPERANTIGEN-LIKE PROTEIN","Staphylococcus aureus",5,"LEU A  28;VAL A  94;ILE A  57;VAL A  77;ILE A  75","None","1.16A","3mwsB-1m4vA:undetectable","3mwsB-1m4vA:20.00"],["5KQY_B_017B101_1","PROTEASE E35D-DRV;PROTEASE E35D-DRV","1m4v","SET3, SUPERANTIGEN-LIKE PROTEIN","Staphylococcus aureus",5,"LEU A  28;VAL A  94;ILE A  57;VAL A  77;ILE A  75","None","1.13A","5kqyA-1m4vA:undetectable","5kqyA-1m4vA:22.10"],["6FGC_A_ACTA811_0","GEPHYRIN","1m4v","SET3, SUPERANTIGEN-LIKE PROTEIN","Staphylococcus aureus",3,"LEU A 148;LEU A 178;ARG A 145","None","0.62A","6fgcA-1m4vA:undetectable","6fgcA-1m4vA:18.46"],["6FGD_A_ACTA810_0","GEPHYRIN","1m4v","SET3, SUPERANTIGEN-LIKE PROTEIN","Staphylococcus aureus",3,"LEU A 148;LEU A 178;ARG A 145","None","0.62A","6fgdA-1m4vA:undetectable","6fgdA-1m4vA:18.46"]]