SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m53'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 LEU A 137
ALA A  89
ALA A  51
THR A 402
TYR A 520
 None
 1.12A 1cbrA-1m53A:
undetectable		 1cbrA-1m53A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 LEU A 137
ALA A  89
ALA A  51
THR A 402
TYR A 520
 None
 1.11A 1cbrB-1m53A:
undetectable		 1cbrB-1m53A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		7 / 12 TYR A 105
ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ARG A 460
 None
 0.81A 1dedB-1m53A:
26.5		 1dedB-1m53A:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 PHE A 551
TRP A 590
GLU A 553
 None
 0.78A 1mogA-1m53A:
0.0		 1mogA-1m53A:
8.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		8 / 12 TYR A 105
HIS A 145
PHE A 205
ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
 None
 1.00A 1mxdA-1m53A:
22.9		 1mxdA-1m53A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 8 ASP A 122
ILE A  92
ILE A  75
GLY A  70
ILE A  69
 None
 1.18A 1sh9A-1m53A:
undetectable		 1sh9A-1m53A:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOX_A_THAA400_1
(HISTAMINE
N-METHYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 PHE A 344
PHE A 551
TYR A 536
TYR A 523
 None
 1.18A 2aoxA-1m53A:
undetectable		 2aoxA-1m53A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 LYS A 337
ASP A 322
ASP A 302
 None
 0.98A 2br4A-1m53A:
undetectable		 2br4A-1m53A:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_C_H4BC1002_1
(HYPOTHETICAL PROTEIN
PH0634)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 6 TYR A 105
ASP A 102
PHE A 205
THR A 242
 None
 1.10A 2dttB-1m53A:
0.0
2dttC-1m53A:
0.0		 2dttB-1m53A:
13.43
2dttC-1m53A:
13.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQY_A_ADNA400_1
(MEMBRANE LIPOPROTEIN
TMPC)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ASP A 426
PHE A 432
PHE A 263
PHE A 186
GLY A 187
 None
 1.41A 2fqyA-1m53A:
undetectable		 2fqyA-1m53A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMJ_A_ACRA1001_1
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ASP A 241
ASP A 426
ASP A 369
PHE A 186
ALA A 206
 None
 1.33A 2qmjA-1m53A:
14.2		 2qmjA-1m53A:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_D_2FAD500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 4 LEU A 546
GLN A 524
THR A 537
THR A 559
 None
 1.47A 2zj0D-1m53A:
undetectable		 2zj0D-1m53A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 10 GLU A 495
VAL A 374
ALA A 373
PHE A 463
THR A 414
 None
 1.24A 3a3yA-1m53A:
undetectable		 3a3yA-1m53A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.71A 3aicA-1m53A:
4.7		 3aicA-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.74A 3aicB-1m53A:
7.2		 3aicB-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		7 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
TYR A 105
 None
 0.70A 3aicC-1m53A:
7.4		 3aicC-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
GLU A 295
HIS A 368
ASP A 369
TYR A 105
GLN A 209
 None
 1.03A 3aicC-1m53A:
7.4		 3aicC-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.79A 3aicD-1m53A:
5.8		 3aicD-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.78A 3aicE-1m53A:
7.4		 3aicE-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.78A 3aicF-1m53A:
7.4		 3aicF-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.74A 3aicG-1m53A:
4.0		 3aicG-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
GLN A 209
 None
 0.98A 3aicG-1m53A:
4.0		 3aicG-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
ASP A 102
 None
 0.78A 3aicH-1m53A:
6.7		 3aicH-1m53A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1010_1
(SERUM ALBUMIN)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 LEU A 212
ILE A 143
PHE A 240
ARG A 220
 None
 0.75A 3b9lA-1m53A:
0.0		 3b9lA-1m53A:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 5 PRO A  94
ILE A  92
PRO A  58
TYR A  57
 None
 1.12A 3d9lA-1m53A:
undetectable
3d9lY-1m53A:
undetectable		 3d9lA-1m53A:
13.11
3d9lY-1m53A:
2.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_B_URFB521_1
(RNA DEPENDENT RNA
POLYMERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 4 ARG A 475
ASP A  67
ASP A  63
ASP A  71
 None
 1.50A 3naiB-1m53A:
0.0		 3naiB-1m53A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 TRP A 384
VAL A 374
TRP A 590
 None
 1.17A 3zq8C-1m53A:
undetectable
3zq8D-1m53A:
undetectable		 3zq8C-1m53A:
4.64
3zq8D-1m53A:
4.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 ARG A  59
ARG A 460
ILE A  69
 None
 0.89A 4b7qC-1m53A:
undetectable		 4b7qC-1m53A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B9Z_A_ACRA1818_1
(ALPHA-GLUCOSIDASE,
PUTATIVE, ADG31B)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ASP A 241
ASP A 369
GLU A 428
ARG A 456
ASP A 102
 None
 1.46A 4b9zA-1m53A:
15.8		 4b9zA-1m53A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 GLY A 593
VAL A 594
ILE A 395
PHE A 551
 None
 0.91A 4fglD-1m53A:
0.0		 4fglD-1m53A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 7 GLY A 593
VAL A 594
ILE A 395
PHE A 551
 None
 0.92A 4fglC-1m53A:
undetectable		 4fglC-1m53A:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 ARG A 335
GLU A 446
ASN A 450
 None
 0.87A 4imaD-1m53A:
9.7		 4imaD-1m53A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		3 / 3 ARG A 335
GLU A 446
ASN A 450
 None
 0.84A 4ip7D-1m53A:
5.4		 4ip7D-1m53A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 PRO A  99
ASP A 106
ALA A 206
SER A 147
 None
 1.01A 4k0bB-1m53A:
undetectable		 4k0bB-1m53A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 PRO A  99
ASP A 106
ALA A 206
SER A 147
 None
 1.02A 4l7iB-1m53A:
undetectable		 4l7iB-1m53A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		6 / 12 ILE A 571
ALA A 592
ILE A 395
PRO A 403
VAL A  52
THR A 573
 None
 1.49A 4m2xG-1m53A:
undetectable		 4m2xG-1m53A:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 6 ASN A 503
GLU A 495
GLU A 410
TYR A 505
 None
 1.31A 4mi4A-1m53A:
1.0		 4mi4A-1m53A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 7 ASN A 503
GLU A 495
GLU A 410
TYR A 505
 None
 1.15A 4mj8C-1m53A:
0.0		 4mj8C-1m53A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 5 ASN A 100
GLY A 104
ASP A 124
ASP A  97
 None
 1.13A 4n48B-1m53A:
undetectable		 4n48B-1m53A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 4 ASN A 100
GLY A 104
ASP A 124
ASP A  97
 None
 1.14A 4n49A-1m53A:
1.1		 4n49A-1m53A:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 7 ASN A 503
GLU A 495
GLU A 410
TYR A 505
 None
 1.28A 4r87I-1m53A:
0.7		 4r87I-1m53A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ASP A 525
TYR A 523
SER A 349
ALA A 401
TYR A 534
 None
 1.45A 4u15B-1m53A:
undetectable		 4u15B-1m53A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ARG A 239
ASP A 241
GLU A 295
HIS A 368
ASP A 369
 None
 0.46A 5csyB-1m53A:
17.2		 5csyB-1m53A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 11 TYR A  96
ILE A 113
ILE A  72
PHE A 123
LEU A 137
 None
 0.93A 5e4dB-1m53A:
0.0		 5e4dB-1m53A:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 8 ILE A 482
ILE A  92
ILE A 113
ILE A  75
ASP A  71
 None
 1.37A 5hi2A-1m53A:
undetectable		 5hi2A-1m53A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 6 ARG A 165
GLY A 198
ASP A 194
ASP A 172
 None
 0.96A 5hp1A-1m53A:
undetectable		 5hp1A-1m53A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 5 TYR A 504
SER A 388
ALA A 391
GLN A 574
 None
 1.42A 5n0tA-1m53A:
0.0		 5n0tA-1m53A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUZ_A_SAMA3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 GLY A 251
SER A 247
TYR A 204
PHE A 169
ARG A 171
 None
 1.48A 5tuzA-1m53A:
undetectable		 5tuzA-1m53A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUZ_B_SAMB3001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
EHMT1)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 GLY A 251
SER A 247
TYR A 204
PHE A 169
ARG A 171
 None
 1.48A 5tuzB-1m53A:
undetectable		 5tuzB-1m53A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_B_C2FB702_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 ASN A 100
GLY A 104
GLY A  70
SER A  60
ILE A  69
 None
 1.17A 5vooB-1m53A:
9.8		 5vooB-1m53A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		5 / 12 TYR A 105
HIS A 145
ASP A 241
HIS A 368
ASP A 369
 None
 0.43A 6ag0A-1m53A:
19.5		 6ag0A-1m53A:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 8 TRP A  48
TYR A 520
GLU A  50
TRP A 360
 None
 1.05A 6c71B-1m53A:
undetectable		 6c71B-1m53A:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 7 TRP A 230
HIS A  95
ARG A 239
ASP A 140
 None
 1.24A 6mn4E-1m53A:
0.0		 6mn4E-1m53A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N7F_A_RBFA502_0
(PUTATIVE GLUTATHIONE
REDUCTASE (GR))		 1m53 ISOMALTULOSE
SYNTHASE
(Klebsiella
sp.
LX3) 		4 / 7 GLY A  70
HIS A 368
ASN A  93
GLY A 104
 None
 0.94A 6n7fA-1m53A:
0.8		 6n7fA-1m53A:
10.63