SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m5q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E7B_A_HLTA4001_1 (SERUM ALBUMIN)	1m5q	SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG (Pyrobaculum aerophilum)	4 / 5	ARG A 83 LYS A 87 ALA A 86 ASP A 81	None	1.05A	1e7bA-1m5qA: undetectable	1e7bA-1m5qA: 12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DAJ_B_0HKB2000_2 (MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME)	1m5q	SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG (Pyrobaculum aerophilum)	3 / 3	ASN A 46 LEU A 28 PHE A 64	None	0.76A	4dajB-1m5qA: undetectable	4dajB-1m5qA: 15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IBL_A_H98A501_0 (THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR)	1m5q	SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG (Pyrobaculum aerophilum)	5 / 12	VAL A 119 VAL A 112 ASP A 81 PHE A 85 PHE A 93	None	1.42A	6iblA-1m5qA: undetectable	6iblA-1m5qA: 15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IBL_B_H98B501_0 (THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR)	1m5q	SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG (Pyrobaculum aerophilum)	5 / 12	VAL A 119 VAL A 112 ASP A 81 PHE A 85 PHE A 93	None	1.41A	6iblB-1m5qA: undetectable	6iblB-1m5qA: 15.42

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E7B_A_HLTA4001_1","SERUM ALBUMIN","1m5q","SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG","Pyrobaculum aerophilum",4,"ARG A  83;LYS A  87;ALA A  86;ASP A  81","None","1.05A","1e7bA-1m5qA:undetectable","1e7bA-1m5qA:12.26"],["4DAJ_B_0HKB2000_2","MUSCARINIC ACETYLCHOLINE RECEPTOR M3, LYSOZYME","1m5q","SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG","Pyrobaculum aerophilum",3,"ASN A  46;LEU A  28;PHE A  64","None","0.76A","4dajB-1m5qA:undetectable","4dajB-1m5qA:15.35"],["6IBL_A_H98A501_0","THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR","1m5q","SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG","Pyrobaculum aerophilum",5,"VAL A 119;VAL A 112;ASP A  81;PHE A  85;PHE A  93","None","1.42A","6iblA-1m5qA:undetectable","6iblA-1m5qA:15.42"],["6IBL_B_H98B501_0","THIOREDOXIN 1,BETA-1 ADRENERGIC RECEPTOR","1m5q","SMALL NUCLEAR RIBONUCLEOPROTEIN HOMOLOG","Pyrobaculum aerophilum",5,"VAL A 119;VAL A 112;ASP A  81;PHE A  85;PHE A  93","None","1.41A","6iblB-1m5qA:undetectable","6iblB-1m5qA:15.42"]]