SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m5s'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JOL_B_FFOB361_0 (DIHYDROFOLATE REDUCTASE)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ILE A  76 ALA A  40 ARG A 137 PRO A 109 THR A  41	None	1.06A	1jolB-1m5sA: undetectable	1jolB-1m5sA: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIK_A_ADNA699_1 (ADENOSINE KINASE)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ILE A 249 LEU A 190 GLY A 163 GLY A 164 THR A 193	None	1.16A	1likA-1m5sA: undetectable	1likA-1m5sA: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIN_A_TFPA156_1 (CALMODULIN)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 8	ILE A 265 ILE A   8 GLU A   2 VAL A   6 ILE A 277	None	1.42A	1linA-1m5sA: undetectable	1linA-1m5sA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PRG_A_BRLA1_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	3 / 3	ILE A 168 ILE A 201 LEU A 296	None	0.56A	2prgA-1m5sA: undetectable	2prgA-1m5sA: 22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_B_SAMB602_0 (HYPOTHETICAL PROTEIN)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ALA A 111 ALA A 151 VAL A 104 PHE A 119 ASP A 115	None	1.00A	2yvlB-1m5sA: undetectable	2yvlB-1m5sA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_C_SAMC604_0 (HYPOTHETICAL PROTEIN)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ALA A 111 ALA A 151 VAL A 104 PHE A 119 ASP A 115	None	0.97A	2yvlC-1m5sA: undetectable	2yvlC-1m5sA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YVL_D_SAMD603_0 (HYPOTHETICAL PROTEIN)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ALA A 111 ALA A 151 VAL A 104 PHE A 119 ASP A 115	None	0.98A	2yvlD-1m5sA: undetectable	2yvlD-1m5sA: 23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 11	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.10A	3g88A-1m5sA: 0.0	3g88A-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G88_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 11	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.10A	3g88B-1m5sA: undetectable	3g88B-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.04A	3g89A-1m5sA: 0.0	3g89A-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G89_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 11	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.04A	3g89B-1m5sA: 0.0	3g89B-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.06A	3g8bA-1m5sA: 0.0	3g8bA-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE G)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	GLY A 273 GLY A 170 PHE A 169 ASP A 171 ALA A 179	None	1.08A	3g8bB-1m5sA: 0.0	3g8bB-1m5sA: 23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NU6_B_478B401_1 (PROTEASE)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 10	ALA A  36 VAL A  72 GLY A  42 VAL A  23 ILE A  25	None	0.92A	3nu6A-1m5sA: undetectable	3nu6A-1m5sA: 15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3REM_A_SALA301_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	4 / 8	ARG A 137 ARG A  22 ILE A 155 GLN A 114	None	1.04A	3remA-1m5sA: undetectable	3remA-1m5sA: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OAD_A_CLMA206_0 (GNAT SUPERFAMILY ACETYLTRANSFERASE PA4794)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	4 / 4	ALA A 176 ALA A 179 ALA A 180 ALA A 183	None	0.13A	4oadA-1m5sA: 0.6	4oadA-1m5sA: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTW_A_DB8A1101_2 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-3)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	3 / 3	LEU A  84 LEU A 121 ASN A 106	None	0.68A	4otwA-1m5sA: undetectable	4otwA-1m5sA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E72_A_SAMA400_0 (N2, N2-DIMETHYLGUANOSINE TRNA METHYLTRANSFERASE)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	GLY A 251 ILE A 194 ILE A 265 ALA A 183 THR A 195	None	1.07A	5e72A-1m5sA: 3.0	5e72A-1m5sA: 24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ODQ_A_ACTA703_0 (HETERODISULFIDE REDUCTASE, SUBUNIT A)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	4 / 6	ALA A 135 PRO A  66 PHE A 105 GLU A 152	None	1.32A	5odqA-1m5sA: undetectable	5odqA-1m5sA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZW4_A_SAMA302_0 (PUTATIVE O-METHYLTRANSFERASE YRRM)	1m5s	FORMYLMETHANOFURAN-- TETRAHYDROMETHANOPTE RIN FORMYLTRANSFERASE (Methanosarcina barkeri)	5 / 12	ILE A 249 GLY A  55 ALA A  40 ALA A  54 ALA A  44	None	1.05A	5zw4A-1m5sA: undetectable	5zw4A-1m5sA: 22.85