SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m5z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z11_D_8MOD501_0 (CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6)	1m5z	AMPA RECEPTOR INTERACTING PROTEIN (Rattus norvegicus)	5 / 10	VAL A 25 ILE A 54 GLY A 60 ILE A 91 LEU A 100	None	1.11A	1z11D-1m5zA: undetectable	1z11D-1m5zA: 12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CJT_O_SAMO302_0 (RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE)	1m5z	AMPA RECEPTOR INTERACTING PROTEIN (Rattus norvegicus)	5 / 12	LEU A 65 GLY A 60 GLY A 58 LEU A 27 LEU A 98	None	0.96A	3cjtO-1m5zA: undetectable	3cjtO-1m5zA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_2 (NS3 PROTEASE, NS4A PROTEIN)	1m5z	AMPA RECEPTOR INTERACTING PROTEIN (Rattus norvegicus)	3 / 3	TYR A 68 LEU A 90 ARG A 70	None	0.55A	3sufB-1m5zA: 0.0	3sufB-1m5zA: 20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TBG_D_RTZD2_1 (CYTOCHROME P450 2D6)	1m5z	AMPA RECEPTOR INTERACTING PROTEIN (Rattus norvegicus)	5 / 9	PHE A 38 LEU A 71 THR A 79 VAL A 87 ILE A 91	None	1.03A	3tbgD-1m5zA: 0.0	3tbgD-1m5zA: 11.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_B_NPSB603_1 (SERUM ALBUMIN)	1m5z	AMPA RECEPTOR INTERACTING PROTEIN (Rattus norvegicus)	5 / 11	LEU A 22 ARG A 104 VAL A 25 LEU A 100 LEU A 72	None	1.21A	4or0B-1m5zA: undetectable	4or0B-1m5zA: 10.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z11_D_8MOD501_0","CYTOCHROME P450, FAMILY 2, SUBFAMILY A, POLYPEPTIDE 6","1m5z","AMPA RECEPTOR INTERACTING PROTEIN","Rattus norvegicus",5,"VAL A  25;ILE A  54;GLY A  60;ILE A  91;LEU A 100","None","1.11A","1z11D-1m5zA:undetectable","1z11D-1m5zA:12.23"],["3CJT_O_SAMO302_0","RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE","1m5z","AMPA RECEPTOR INTERACTING PROTEIN","Rattus norvegicus",5,"LEU A  65;GLY A  60;GLY A  58;LEU A  27;LEU A  98","None","0.96A","3cjtO-1m5zA:undetectable","3cjtO-1m5zA:18.97"],["3SUF_B_SUEB1201_2","NS3 PROTEASE, NS4A PROTEIN","1m5z","AMPA RECEPTOR INTERACTING PROTEIN","Rattus norvegicus",3,"TYR A  68;LEU A  90;ARG A  70","None","0.55A","3sufB-1m5zA:0.0","3sufB-1m5zA:20.83"],["3TBG_D_RTZD2_1","CYTOCHROME P450 2D6","1m5z","AMPA RECEPTOR INTERACTING PROTEIN","Rattus norvegicus",5,"PHE A  38;LEU A  71;THR A  79;VAL A  87;ILE A  91","None","1.03A","3tbgD-1m5zA:0.0","3tbgD-1m5zA:11.45"],["4OR0_B_NPSB603_1","SERUM ALBUMIN","1m5z","AMPA RECEPTOR INTERACTING PROTEIN","Rattus norvegicus",5,"LEU A  22;ARG A 104;VAL A  25;LEU A 100;LEU A  72","None","1.21A","4or0B-1m5zA:undetectable","4or0B-1m5zA:10.03"]]