SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1m64'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4S_A_TPVA201_2
(PROTEIN (HIV-1
PROTEASE))		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 8 LEU A 154
ALA A 141
GLY A 533
ILE A 553
VAL A 131
 None
None
FAD  A3000 (-3.4A)
FAD  A3000 (-3.6A)
None
 1.22A 1d4sB-1m64A:
undetectable		 1d4sB-1m64A:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 THR A 367
PRO A 501
THR A 500
 None
 0.88A 1dscC-1m64A:
undetectable		 1dscC-1m64A:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 THR A 500
PRO A 366
THR A 367
 None
 0.96A 1dscC-1m64A:
undetectable		 1dscC-1m64A:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 THR A 500
THR A 367
PRO A 501
 None
 0.84A 1dscC-1m64A:
undetectable		 1dscC-1m64A:
2.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_A_IPHA802_0
(PHENOL HYDROXYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.48A 1fohA-1m64A:
14.1		 1fohA-1m64A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_B_IPHB802_0
(PHENOL HYDROXYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.50A 1fohB-1m64A:
14.1		 1fohB-1m64A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOH_C_IPHC802_0
(PHENOL HYDROXYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.49A 1fohC-1m64A:
7.0		 1fohC-1m64A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 11 VAL A 253
GLY A 254
GLY A 170
MET A 375
HIS A 505
 None
None
FAD  A3000 ( 3.4A)
FAD  A3000 ( 3.5A)
FAD  A3000 (-4.1A)
 1.21A 1iolA-1m64A:
4.7		 1iolA-1m64A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 11 LEU A 356
GLY A 354
VAL A 281
LEU A 529
LEU A 346
 None
 1.33A 1mx1B-1m64A:
undetectable		 1mx1B-1m64A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA732_1
(ALPHA AMYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 GLY A 382
GLY A 250
GLY A 249
ASP A 232
ARG A 246
 None
 1.12A 1mxdA-1m64A:
undetectable		 1mxdA-1m64A:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 7 ILE A 409
PRO A 501
PHE A 333
ALA A 364
 None
 0.92A 1oniD-1m64A:
undetectable
1oniE-1m64A:
undetectable		 1oniD-1m64A:
17.90
1oniE-1m64A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 6 PHE A 333
ALA A 364
ILE A 409
PRO A 501
 None
 0.96A 1oniH-1m64A:
undetectable
1oniI-1m64A:
undetectable		 1oniH-1m64A:
17.90
1oniI-1m64A:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 7 VAL A 294
GLY A 278
ILE A 153
VAL A 130
 None
FAD  A3000 (-3.8A)
None
None
 0.82A 1p2yA-1m64A:
undetectable		 1p2yA-1m64A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_A_IPHA6012_0
(PHENOL
2-MONOOXYGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.48A 1pn0A-1m64A:
14.1		 1pn0A-1m64A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_B_IPHB6022_0
(PHENOL
2-MONOOXYGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.50A 1pn0B-1m64A:
14.2		 1pn0B-1m64A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_C_IPHC6032_0
(PHENOL
2-MONOOXYGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.49A 1pn0C-1m64A:
13.9		 1pn0C-1m64A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PN0_D_IPHD6042_0
(PHENOL
2-MONOOXYGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 345
VAL A 348
ARG A 277
ILE A 105
GLY A 343
 FAD  A3000 ( 4.6A)
None
None
None
None
 1.50A 1pn0D-1m64A:
13.9		 1pn0D-1m64A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 ASN A 383
GLY A 250
ASN A 484
GLY A 237
ILE A 399
 None
 1.22A 1q8jB-1m64A:
undetectable		 1q8jB-1m64A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 GLY A 547
GLY A 171
GLY A 234
MET A 235
ASP A 552
 FAD  A3000 ( 3.2A)
FAD  A3000 (-4.2A)
None
None
None
 1.04A 2b25A-1m64A:
2.9		 2b25A-1m64A:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 VAL A 258
ILE A 554
LYS A 166
ILE A 553
ALA A 312
 None
None
None
FAD  A3000 (-3.6A)
None
 1.14A 2gj5A-1m64A:
undetectable		 2gj5A-1m64A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 ALA A 165
GLY A 533
SER A 140
 FAD  A3000 (-3.3A)
FAD  A3000 (-3.4A)
None
 0.55A 2ivuA-1m64A:
undetectable		 2ivuA-1m64A:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCU_A_TYLA3001_1
(LACTOTRANSFERRIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 LEU A  29
TYR A 298
GLY A 296
 HEM  A 801 ( 4.9A)
HEM  A 801 ( 4.9A)
None
 0.63A 2ocuA-1m64A:
undetectable		 2ocuA-1m64A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 ALA A 312
ALA A 165
GLY A 162
GLY A 136
ILE A 553
 None
FAD  A3000 (-3.3A)
None
FAD  A3000 (-4.1A)
FAD  A3000 (-3.6A)
 1.26A 2v7bA-1m64A:
undetectable		 2v7bA-1m64A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 ALA A 312
ALA A 165
GLY A 163
GLY A 136
ILE A 553
 None
FAD  A3000 (-3.3A)
FAD  A3000 (-3.2A)
FAD  A3000 (-4.1A)
FAD  A3000 (-3.6A)
 1.36A 2v7bA-1m64A:
undetectable		 2v7bA-1m64A:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 ARG A 426
GLU A  53
SER A 430
 None
 0.90A 2xkkA-1m64A:
undetectable
2xkkC-1m64A:
undetectable		 2xkkA-1m64A:
21.41
2xkkC-1m64A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DHIC32_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 6 GLY A 509
GLY A 537
GLY A 538
GLY A 508
GLY A 541
 NA  A3002 ( 4.7A)
NA  A3002 ( 4.5A)
None
NA  A3002 (-4.1A)
None
 1.18A 3bogA-1m64A:
0.0
3bogC-1m64A:
0.0		 3bogA-1m64A:
undetectable
3bogC-1m64A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 8 ALA A 169
GLY A 546
PRO A 366
THR A 367
 FUM  A3001 (-4.0A)
FUM  A3001 (-3.3A)
None
None
 0.71A 3el9A-1m64A:
undetectable		 3el9A-1m64A:
11.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM6_A_017A200_1
(PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 8 ALA A 308
ASP A 307
ASP A 128
LEU A 282
VAL A 132
 None
None
None
None
FAD  A3000 (-4.8A)
 1.43A 3em6A-1m64A:
undetectable		 3em6A-1m64A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G88_B_SAMB303_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE G)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 11 GLY A 561
GLY A 557
PHE A 556
ALA A 142
ALA A 150
 None
 1.10A 3g88B-1m64A:
0.5		 3g88B-1m64A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_2
(PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 GLY A 234
ALA A 244
GLY A 237
ILE A 399
THR A 377
 None
None
None
None
FUM  A3001 (-3.7A)
 0.99A 3gguB-1m64A:
undetectable		 3gguB-1m64A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 LEU A 461
GLY A 458
LEU A 447
ILE A 420
ALA A 444
 None
 1.10A 3gwwA-1m64A:
undetectable		 3gwwA-1m64A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 HIS A 504
HIS A 365
MET A 375
 FUM  A3001 ( 4.1A)
FUM  A3001 (-4.2A)
FAD  A3000 ( 3.5A)
 1.03A 3mihA-1m64A:
0.0		 3mihA-1m64A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_1
(HIV-1 PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 LEU A 559
GLY A 531
ALA A 532
GLY A 537
VAL A 211
 None
None
None
NA  A3002 ( 4.5A)
None
 1.03A 3oxwA-1m64A:
undetectable		 3oxwA-1m64A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_D_017D200_1
(HIV-1 PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 LEU A 559
GLY A 531
ALA A 532
GLY A 537
VAL A 211
 None
None
None
NA  A3002 ( 4.5A)
None
 1.03A 3oxwC-1m64A:
undetectable		 3oxwC-1m64A:
11.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 GLU A 158
GLY A 314
VAL A 342
ALA A 165
ASP A 552
 FAD  A3000 (-4.9A)
FAD  A3000 (-3.3A)
None
FAD  A3000 (-3.3A)
None
 1.29A 3qowA-1m64A:
undetectable		 3qowA-1m64A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 8 GLY A 354
ALA A 349
ASP A 347
GLY A 509
THR A 313
 None
None
None
NA  A3002 ( 4.7A)
FAD  A3000 (-3.9A)
 1.42A 3so9A-1m64A:
undetectable		 3so9A-1m64A:
9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 GLY A 340
ASP A 344
GLY A 163
THR A 313
ALA A 312
 None
FAD  A3000 (-3.4A)
FAD  A3000 (-3.2A)
FAD  A3000 (-3.9A)
None
 1.10A 3sugA-1m64A:
undetectable		 3sugA-1m64A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 PHE A  88
CYH A  82
HIS A  86
 HEM  A 804 (-4.6A)
HEM  A 804 (-2.5A)
HEM  A 804 (-3.3A)
 1.12A 3u9fF-1m64A:
undetectable		 3u9fF-1m64A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 PHE A  88
CYH A  82
HIS A  86
 HEM  A 804 (-4.6A)
HEM  A 804 (-2.5A)
HEM  A 804 (-3.3A)
 1.18A 3u9fG-1m64A:
undetectable		 3u9fG-1m64A:
17.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 11 GLY A 451
ASP A 457
ALA A 460
GLY A 458
VAL A 388
 None
 1.35A 4c5lA-1m64A:
2.7		 4c5lA-1m64A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 GLY A 451
ASP A 457
ALA A 460
GLY A 458
VAL A 388
 None
 1.37A 4c5lB-1m64A:
undetectable		 4c5lB-1m64A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 451
ASP A 457
ALA A 460
GLY A 458
VAL A 388
 None
 1.35A 4c5lC-1m64A:
undetectable		 4c5lC-1m64A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 451
ASP A 457
ALA A 460
GLY A 458
VAL A 388
 None
 1.39A 4c5lD-1m64A:
undetectable		 4c5lD-1m64A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 451
ASP A 457
ALA A 460
GLY A 458
VAL A 388
 None
 1.35A 4c5nD-1m64A:
undetectable		 4c5nD-1m64A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		3 / 3 LEU A  24
GLU A  23
SER A  25
 HEM  A 801 ( 4.5A)
None
None
 0.84A 4ccqA-1m64A:
15.2		 4ccqA-1m64A:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R21_A_STRA601_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 6 ALA A 165
ILE A 143
GLY A 138
ILE A 550
 FAD  A3000 (-3.3A)
None
None
FAD  A3000 (-4.2A)
 0.78A 4r21A-1m64A:
undetectable		 4r21A-1m64A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJZ_A_BEZA1001_0
(BENZOATE-COENZYME A
LIGASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 8 ALA A 532
GLY A 557
ALA A 141
GLY A 138
 None
 0.63A 4zjzA-1m64A:
undetectable		 4zjzA-1m64A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 7 ALA A 341
GLU A 156
GLY A 314
GLY A 345
 None
FAD  A3000 (-2.7A)
FAD  A3000 (-3.3A)
FAD  A3000 ( 4.6A)
 0.82A 5e26A-1m64A:
undetectable
5e26B-1m64A:
undetectable		 5e26A-1m64A:
21.66
5e26B-1m64A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 7 GLU A 156
GLY A 314
GLY A 345
ALA A 341
 FAD  A3000 (-2.7A)
FAD  A3000 (-3.3A)
FAD  A3000 ( 4.6A)
None
 0.85A 5e26C-1m64A:
0.0
5e26D-1m64A:
undetectable		 5e26C-1m64A:
21.66
5e26D-1m64A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 5 THR A  50
ALA A  47
THR A  49
HIS A  58
 HEM  A 803 ( 4.8A)
None
None
HEM  A 803 (-3.3A)
 1.32A 5ecmA-1m64A:
undetectable		 5ecmA-1m64A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F1A_B_SALB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 7 LEU A 154
GLY A 138
ALA A 137
SER A 140
 None
None
FAD  A3000 (-3.5A)
None
 0.90A 5f1aB-1m64A:
0.0		 5f1aB-1m64A:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 ILE A 155
GLY A 278
ASP A 344
LEU A 154
GLU A 156
 None
FAD  A3000 (-3.8A)
FAD  A3000 (-3.4A)
None
FAD  A3000 (-2.7A)
 1.24A 5hw4A-1m64A:
undetectable		 5hw4A-1m64A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_B_SAMB801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 11 ILE A 155
GLY A 278
ASP A 344
LEU A 154
GLU A 156
 None
FAD  A3000 (-3.8A)
FAD  A3000 (-3.4A)
None
FAD  A3000 (-2.7A)
 1.20A 5hw4B-1m64A:
undetectable		 5hw4B-1m64A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 ALA A 516
GLY A 533
ILE A 553
VAL A 131
ILE A 310
 None
FAD  A3000 (-3.4A)
FAD  A3000 (-3.6A)
None
None
 1.05A 5kr1A-1m64A:
undetectable		 5kr1A-1m64A:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		4 / 8 ILE A 409
ALA A 417
PHE A 395
PRO A 483
 None
 0.78A 5m0oC-1m64A:
0.0		 5m0oC-1m64A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_0
(METHYLTRANSFERASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 ALA A 265
GLY A 138
TYR A 262
ALA A 532
ALA A 141
 None
 1.10A 5n5dA-1m64A:
3.0		 5n5dA-1m64A:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 12 VAL A 220
ASP A 221
HIS A 245
ALA A 174
THR A 186
 None
 1.13A 5nd3B-1m64A:
undetectable		 5nd3B-1m64A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 10 GLY A 138
GLY A 136
LEU A 559
ARG A 558
ALA A 560
 None
FAD  A3000 (-4.1A)
None
None
None
 1.12A 5o96E-1m64A:
undetectable
5o96F-1m64A:
undetectable		 5o96E-1m64A:
16.40
5o96F-1m64A:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 VAL A 525
GLY A 537
VAL A 510
ASP A 205
GLY A 538
 None
NA  A3002 ( 4.5A)
None
None
None
 1.40A 5zniA-1m64A:
undetectable		 5zniA-1m64A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 1m64 FLAVOCYTOCHROME C3
(Shewanella
frigidimarina) 		5 / 9 ALA A 137
SER A 140
ALA A 165
VAL A 257
GLY A 162
 FAD  A3000 (-3.5A)
None
FAD  A3000 (-3.3A)
None
None
 1.08A 6bklA-1m64A:
undetectable
6bklB-1m64A:
undetectable
6bklC-1m64A:
undetectable
6bklD-1m64A:
undetectable		 6bklA-1m64A:
3.93
6bklB-1m64A:
3.93
6bklC-1m64A:
3.93
6bklD-1m64A:
3.93